A5080520324- Advanced Neuroimaging Techniques and Applications
- Cerebral Palsy and Movement Disorders
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Epilepsy research and treatment
- Peripheral Nerve Disorders
- Peripheral Neuropathies and Disorders
- Autoimmune Neurological Disorders and Treatments
- Infectious Encephalopathies and Encephalitis
- Spinal Dysraphism and Malformations
- Cerebrospinal fluid and hydrocephalus
- Fetal and Pediatric Neurological Disorders
University Hospital Bonn
2021-2023
University of Bonn
2020
Abstract Motor function after hemispheric lesions has been associated with the structural integrity of either pyramidal tract (PT) or alternate motor fibers (aMF). In this study, we aimed to differentially characterize roles PT and aMF in compensation by relating diffusion-tensor-imaging-derived parameters white matter microstructure measures proximal distal patients hemispherotomy. Twenty-five (13 women; mean age: 21.1 years) hemispherotomy (at 12.4 underwent Diffusion Tensor Imaging...
<h3>BACKGROUND AND PURPOSE:</h3> Limbic encephalitis is an autoimmune disease. A variety of autoantibodies have been associated with different subtypes limbic encephalitis, whereas its MR imaging signature uniformly characterized by mesiotemporal abnormalities across subtypes. Here, we hypothesized that patients would show subtype-specific structural correlates, which could be classified supervised machine learning on individual level. <h3>MATERIALS METHODS:</h3> T1WI MPRAGE scans from 46...
Abstract Selective amygdalohippocampectomy is an effective treatment for patients with therapy-refractory temporal lobe epilepsy but may cause visual field defect (VFD). Here, we aimed to describe tissue-specific pre- and postoperative imaging correlates of the VFD severity using whole-brain analyses from voxel- network-level. Twenty-eight underwent MRI (T1-MPRAGE Diffusion Tensor Imaging) as well kinetic perimetry according Goldmann standard. We probed gray matter (GM) white (WM)...
Cerebral lesions may cause degeneration and neuroplastic reorganization in both the ipsi- contralesional hemisphere, presumably creating an imbalance of primarily inhibitory interhemispheric influences produced via transcallosal pathways. The two hemispheres are thought to mutually hamper other hemisphere. results preceding white matter be reflected by Diffusion Tensor Imaging-derived diffusivity parameters such as fractional anisotropy (FA). In this study, we applied Imaging (DTI) contrast...
Abstract Background and Purpose Voxel‐based morphometry (VBM) studies of people with focal epilepsies revealed gray matter (GM) alterations in brain regions involved cardiorespiratory regulation, which have been linked to the risk sudden unexpected death epilepsy (SUDEP). It remains unclear whether type localization epileptogenic lesions influence occurrence such alterations. Methods To test hypothesis that VBM autonomic network are independent they reveal structural underpinnings SUDEP...