- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Animal testing and alternatives
- Environmental Toxicology and Ecotoxicology
- Air Quality and Health Impacts
- Pesticide Exposure and Toxicity
- Per- and polyfluoroalkyl substances research
- Carcinogens and Genotoxicity Assessment
- Atmospheric chemistry and aerosols
- Automotive and Human Injury Biomechanics
- Immunotoxicology and immune responses
- Surgical Sutures and Adhesives
- Intestinal and Peritoneal Adhesions
- Advanced Chemical Sensor Technologies
- Air Quality Monitoring and Forecasting
- Biochemical Analysis and Sensing Techniques
- Hernia repair and management
- Environmental Justice and Health Disparities
- Risk Perception and Management
- Traumatic Ocular and Foreign Body Injuries
- Delphi Technique in Research
- Mercury impact and mitigation studies
- Pesticide and Herbicide Environmental Studies
- Flame retardant materials and properties
- Energy and Environment Impacts
Environmental Protection Agency
2018-2024
National Center for Environmental Assessment (EPA)
2018-2023
Triangle
2020
Duke University
2011-2015
Research Triangle Park Foundation
2014
SUNY Upstate Medical University
2009
Duke Medical Center
2009
Le Moyne College
2007
Organophosphate flame retardants (OPFRs) are common replacements for the phased-out polybrominated diphenyl ethers (PBDEs) and have been detected at high concentrations in environmental samples. OPFRs structurally similar to organophosphate pesticides may adversely affect developing nervous system. This study evaluated overt toxicity, uptake, neurobehavioral effects of tris (1,3-dichloro-2-propyl) phosphate (TDCPP), (2-chloroethyl) (TCEP), (1-chloro-2-propyl) (TCPP), (2,3-dibromopropyl)...
Systematic evidence maps (SEMs) are increasingly used to inform decision-making and risk management priority-setting serve as problem formulation tools refine the focus of questions that get addressed in full systematic reviews. Within U.S. Environmental Protection Agency (EPA) Office Research Development (ORD) Integrated Risk Information System (IRIS), SEMs have been data gaps, determine need for updated assessments, assessment priorities, development study evaluation considerations, among...
A key challenge in systematically incorporating mechanistic data into human health assessments is that, compared to studies of apical endpoints, these are both more abundant (mechanistic routinely outnumber other by several orders magnitude) and heterogeneous (e.g. different species, test system, tissue, cell type, exposure paradigm, or specific assays performed). structured decision-making process for organizing, integrating, weighing DNT use risk will improve the consistency efficiency...
Ethanol's taste attributes undoubtedly contribute to the development of drug preference. is both sweet and bitter. Taster status for bitter 6-n-propylthiouracil (PROP) has been proposed as a genetic marker alcoholism; however, human results are conflicting. We collected preference scores tastants in 4 mouse strains selected on basis previously reported preference, with generally accepted idea that inbred mice show minimal within-strain variation. Eighty-eight male (22 per strain)...
Background & Aim: Ethylbenzene is an aromatic hydrocarbon widely used in consumer and industrial applications, including as styrene feedstock paints, glues, fuels. Given that ethylbenzene one of the most highly emitted hazardous air pollutants, it relevant to survey available literature understand potential adverse health effects. Here, we utilize a systematic evidence map (SEM) approach identify epidemiological studies exposure characterize aspects base may support human hazard...