A5055735124- Ferroptosis and cancer prognosis
- Metabolism, Diabetes, and Cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Immune cells in cancer
- Diabetes Management and Research
- Adipose Tissue and Metabolism
- Glioma Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Diabetes and associated disorders
- RNA modifications and cancer
- Advanced Glycation End Products research
- Diabetes Treatment and Management
- Pancreatic function and diabetes
- Diabetic Foot Ulcer Assessment and Management
- Cancer-related molecular mechanisms research
- Cardiovascular Disease and Adiposity
- Retinoids in leukemia and cellular processes
- Cancer, Lipids, and Metabolism
- Retinal Diseases and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Immune Cell Function and Interaction
- MicroRNA in disease regulation
- Epigenetics and DNA Methylation
Soochow University
2011-2024
First Affiliated Hospital of Soochow University
2010-2024
Henan Provincial People's Hospital
2022-2023
Henan University
2022-2023
Zhengzhou University
2022-2023
First Affiliated Hospital of Harbin Medical University
2020-2022
Harbin Medical University
2020-2022
Mahidol University
2012
In recent years, as living standards have continued to improve, the number of diabetes patients in China, along with incidence complications associated disease, has been increasing. Among these complications, diabetic foot disease is one main causes disability and death patients. Due differences economy, culture, religion level medical care available across different regions, preventive treatment methods curative results for vary greatly. multidisciplinary models built around foot, timely...
An intermittent fasting plan consisting of 2 nonconsecutive days and 5 habitual intake per week meal replacement diet (5:2 MR) could provide additional benefits to patients with type diabetes.
Adropin has been identified as potent regulatory hormone implicated in insulin sensitivity and the maintenance of energy homeostasis. The aim current study was to investigate serum adropin concentrations type 2 diabetes mellitus (T2DM) patients fasting status, especially those overweight/obese evaluate relationships between levels metabolic parameters. A total 116 T2DM 60 controls with normal glucose tolerance (NGT) were recruited study. concentration determined using commercial ELISA kits....
Background. Fibroblast growth factor (FGF)-21 has been recently characterized as a potent metabolic regulator, but the physiological role of FGF-21 remains poorly understood. This study was designed to investigate serum levels in type 2 diabetes mellitus (T2DM) patients and explore correlations between its various cardiometabolic parameters humans. Methods. Fifty-four newly diagnosed with T2DM (NDDM), 54 subjects long duration (LDDM), that is, more than 5 years, 35 normal controls...
Neuregulin 4 (Nrg4) and neuregulin 1 (Nrg1) have been shown to play vital roles in several disorders of glucose metabolism. The pathophysiological role Nrg4 Nrg1 gestational diabetes mellitus (GDM), however, remains poorly understood. We assessed the clinical relevance two cytokines patients with GDM.The study recruited 36 GDM 38 age-matched, age (24-28 weeks gestation)-matched, BMI (during pregnancy)-matched controls this study. Serum were measured using ELISA. Inflammatory factors such as...
Glioblastoma is the most common and lethal brain cancer globally. Clinically, this has heterogenous molecular clinical characteristics. Studies have shown that UBE2S highly expressed in many cancers. But its expression profile glioma, correlation with outcomes unknown. RNA sequencing data of glioma samples was downloaded from Chinese Glioma Genome Atlas The Cancer Atlas. A total 114 cases tissue (WHO grades II-IV) were used to conduct protein assays. biological characteristics UBE2S,...
Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type present several levels of islet function as well variable number and islet-specific autoantibodies. This study was to investigate prevalence heterogeneity the autoantibodies clinical phenotypes mellitus; also discussed process failure its risk factors Chinese diabetic patients. A total 1,291 were enrolled this study. Demographic information collected. Laboratory tests including mixed-meal tolerance...
Adipose differentiation-related protein (ADRP) is an adipokine. In vitro and animal studies have verified the role of ADRP in lipid metabolism non-alcoholic fatty liver disease (NAFLD). The aim this study was to evaluate interaction between levels NAFLD type 2 diabetes mellitus (T2DM).Cross-sectional design. A total 142 patients with T2DM were assigned (Group-I) non-NAFLD (Group-II). Anthropometric data collected. Serum biochemical parameters also determined. t test or χ2 conducted compare...
We aim to explore effects of Ketotifen on metabolic profiles, inflammation and oxidative stress. Sprague Dawley (SD) male rats were randomly divided into normal control group (NC) experimental groups, fed with high-sugar fat diet for 6 weeks. Then, diabetes (DM) ketotifen treatment (KT). KT was given via Intragastric 8 weeks the dosage 0.09 mg/kg/d. Fasting plasma glucose (FPG) measured using oxidase-phenol amino phenazone method. insulin (FINS), total cholesterol (TC), triglyceride (TG),...
Background: From an occupational health perspective, one of the hazards in workplace is psychosocial stress. However, literature does not pay enough attention to hazards. This especially true for stress among Thai contract farmers who experience from factors such as state policies, labor market, advanced technologies, and job environment employment working conditions. The results these contribute inequality under globalization. Objective: We constructed a model that explains cause resulting...
Objective To evaluate the efficacy and safety of epalrestat, an aldose reductase inhibitor, epalrestat plus methylcobalamine on diabetic peripheral neuropathy, as compared with methylcobalamine. Methods A total 444 subjects neuropathy were enrolled in study, divided into group(n=145), group(n=143), combined group(n=156). Therapeutic efficacay was assessed terms clinical symptoms physical examinations by using Michigan Neuropathy Screening Instrument(MNSI), electrophysiological...
Introduction: There is a strong bidirectional relationship between nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM), both of which can lead to an increase in harmful metabolism cardiovascular risk. It was discovered that C1q/TNF-related protein 4 (CTRP4) regulates glucolipid feeding behavior. However, the correlation serum CTRP4 NAFLD T2DM patients not yet fully understood. Methods: This study enrolled 188 participants who were separated into distinct groups...
Despite the growing recognition of ITGB3BP as an essential feature various cancers, relationship between and glioma remains unclear. The main aim this study was to determine prognostic diagnostic value in glioma. RNA-Seq microarray data from 2222 patients were included, we found that expression level tissues significantly higher than normal brain tissues. Moreover, can be considered independent risk factor for poor prognosis has great predictive Gene Set Enrichment Analysis results showed...