A5017835726- Ferroptosis and cancer prognosis
- Glioma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Ubiquitin and proteasome pathways
- Circular RNAs in diseases
- Microtubule and mitosis dynamics
- RNA Research and Splicing
- MicroRNA in disease regulation
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- interferon and immune responses
- ATP Synthase and ATPases Research
- Cytokine Signaling Pathways and Interactions
- Luminescence and Fluorescent Materials
- Wound Healing and Treatments
- Nuclear Structure and Function
- RNA regulation and disease
- Bone Metabolism and Diseases
- Power Systems Fault Detection
- DNA Repair Mechanisms
- Power Quality and Harmonics
- Electrospun Nanofibers in Biomedical Applications
- Computational Drug Discovery Methods
- Sulfur Compounds in Biology
- Animal Virus Infections Studies
Henan Provincial People's Hospital
2020-2023
Zhengzhou University
2021-2023
Henan University
2021
Tianjin People's Hospital
2021
Zhengzhou People's Hospital
2021
The appropriate vascularization and anti-inflammatory play an important role in wound healing. Currently, the balance of promoting suitable for accurate healing is still a key issue this field. positive factors controlled release, thermal environment, desired structure, composition can provide ideal comprehensive strategy problem. Herein, we prepared near-infrared (NIR)-responsive MXene nanofibers hydrogel double structure system ([email protected]@AC) with two types loading, deferoxamine...
Abstract Background Cysteine cathepsin C encoded by the CTSC gene is an important member of cysteine family that plays a key role regulation many types tumors. However, whether involved in pathological process glioma has not yet been reported. We comprehensively analyzed data from multiple databases and for first time revealed specific mechanism action glioma, identifying it as novel efficient biomarker diagnosis treatment this brain tumor. Methods The expression its relationship with...
Abstract Background Although many biomarkers have been reported for detecting glioma, the prognosis disease remains poor, and therefore, new need to be identified. GNG5 , which is part of G-protein family, has associated with different malignant tumors, though role in glioma not studied. Therefore, we aimed identify relationship between a biomarker diagnosis treatment gliomas. Methods We used data on more than thousand gliomas from multiple databases clinical determine expression glioma....
Circular RNAs (circRNAs) are implicated in the chemoresistance of human cancers. However, functions circRNA PR/SET domain 2 (circPRDM2) resistance osteosarcoma (OS) to doxorubicin (DXR) unknown.Quantitative real-time polymerase chain reaction (qRT-PCR) assay was conducted determine levels circPRDM2, microRNA-760 (miR-760) and enhancer zeste homolog (EZH2). RNase R used analyze characteristics circPRDM2. IC50 DXR estimated by Cell Counting Kit-8 (CCK-8) assay. Colony formation performed for...
Research has confirmed that extra spindle pole bodies-like 1 (ESPL1), an etiological factor, promotes the malignant progression of cancers. However, relationship between ESPL1 and glioma not yet been demonstrated. The purpose this study was to reveal potential mechanisms ESPL1-mediated progression. Gene expression data detailed clinical information cases were obtained from multiple public databases. Subsequently, a series bioinformatics analyses used elucidate effects on glioma. results...
ETS transcription factor ELK3 (ELK3), a novel oncogene, affects pathological processes and progression of many cancers in human tissues. However, it remains unclear whether ELK3, as key gene, the process gliomas prognosis patients with gliomas. This study aimed to comprehensively systematically reveal correlation between malignant by analyzing clinical sample information stored multiple databases. We revealed putative mechanism involvement identified new efficient biomarker for glioma...
Homeobox D11 (HOXD11) plays an important role in a variety of cancers, but its precise gliomas remains unclear. This study aimed to explore the relationship between HOXD11 and by combining bioinformatics methods with basic experimental validation.Obtain gene expression information clinical glioma non-tumor brain tissue samples from multiple public databases such as TCGA (666 samples), CGGA (749 GEPIA(163 glioblastoma 207 normal control GEO (GSE4290 GSE15824). Nine cases five were collected...
HOXA4 is a novel oncogene that has been observed in many kinds of tumors, but its role during glioma carcinogenesis and clinical significance diagnosing prognosis human remains unknown. In the present study, Chinese Glioma Atlas (CGGA)-RNA sequencing database, CGGA microarray, The Cancer Genome (TCGA)-RNA seq data from 1674 patients were obtained online databases analyzed using quantitative reverse transcription-polymerase chain reaction (RT-qPCR) to detect changes expression level...
The undetectable onset of glioma and the difficulty surgery lead to a poor prognosis. Appropriate biomarkers for diagnosis treatment need be identified. Interleukin‑1 receptor‑associated kinase 4 (IRAK4) is involved in initiation progression cancer. However, up until now, no report has revealed relationship between IRAK4 glioma. present study aimed examine expression glioma, determine if there was clinical outcomes or survival Thousands tissue samples corresponding information were obtained...
Osteosarcoma is a common primary bone tumour in children and adolescents. Circular RNAs (circRNAs) exert vital functions human diseases, including osteosarcoma. Therefore, we explored the role of circ_0016347 osteosarcoma.The real-time quantitative polymerase chain reaction (RT-qPCR) was used to detect expression levels circ_0016347, microRNA-661 (miR-661), Interleukin-6 receptor (IL6R) osteosarcoma tissues cells. The proliferation cells assessed by...
Abstract Background The carcinogenic effect of NUP37 has been reported recently in a variety tumors, but its research the field glioma not paid attention. main purpose this study is to reveal relationship between and prognosis or clinical characteristics patients. Methods First, as retrospective study, included thousands tissue samples based on public databases clinicopathological tissues. Second, series bioinformatics analysis methods were used analyze from multiple such CGGA, TCGA, GEO,...
Despite the growing recognition of ITGB3BP as an essential feature various cancers, relationship between and glioma remains unclear. The main aim this study was to determine prognostic diagnostic value in glioma. RNA-Seq microarray data from 2222 patients were included, we found that expression level tissues significantly higher than normal brain tissues. Moreover, can be considered independent risk factor for poor prognosis has great predictive Gene Set Enrichment Analysis results showed...
Abstract Background: Although many biomarkers have been reported for detecting glioma, the prognosis disease remains poor, and therefore, new need to be identified. GNG5 , which is part of G-protein family, has associated with different malignant tumors, though role in glioma not studied. Therefore, we aimed identify relationship between a biomarker diagnosis treatment gliomas. Methods : We used data on more than thousand gliomas from multiple databases clinical determine expression glioma....
An adaptive reclosing technology is proposed in this paper to prevent reclosure a de-energized distribution line with fault and meanwhile ensure power supply reliability. inverter source connected the low-side of service transformer controlled by thyristor bridge momentarily inject an transient high voltage feeders after tripping. Whether exists can be judged detecting analyzing waveform near downstream side breaker used guide or not. The method doesn't need communication employed both...
Abstract Background: In recent years, some studies have shown that TIMELESS , as an oncogene, is involved in the malignant progression of cancers. However, its relationship with prognosis glioma patients rarely reported. Our purpose to explore role glioma. Main body: Based on 1814 samples from multiple databases such TCGA, CGGA, GEO, we use a variety bioinformatics methods verify mechanism action mRNA protein, appearance analysis, clinical features prognosis. Then, CMap tool predict...
Abstract Trophinin-associated protein ( TROAP ) was originally identified to mediate the embryo transfer process and participate in regulation of microtubules but later found be associated with biological behavior various types cancers. However, there is limited information about role glioma. In this study, thousands glioma samples were obtained from multiple independent datasets detect changes mRNA expression levels glioma, we that compared normal brain tissues, significantly increased at...