A5008073944- Brain Metastases and Treatment
- Cardiovascular Health and Disease Prevention
- Glioma Diagnosis and Treatment
- Non-Invasive Vital Sign Monitoring
- Meningioma and schwannoma management
- Heart Rate Variability and Autonomic Control
- CNS Lymphoma Diagnosis and Treatment
- Management of metastatic bone disease
- Spinal Fractures and Fixation Techniques
- Spinal Dysraphism and Malformations
- Cerebrospinal fluid and hydrocephalus
- Lung Cancer Research Studies
- Traditional Chinese Medicine Studies
- Infections and bacterial resistance
- Orthopedic Infections and Treatments
- Complementary and Alternative Medicine Studies
- Effects of Vibration on Health
- Musculoskeletal pain and rehabilitation
- Infant Development and Preterm Care
- Optical Imaging and Spectroscopy Techniques
- Medical Imaging Techniques and Applications
- Inflammatory mediators and NSAID effects
- Fetal and Pediatric Neurological Disorders
- Acupuncture Treatment Research Studies
- Uterine Myomas and Treatments
National Cancer Center
2012-2024
National Cancer Center
2024
Sangji University
2008-2020
Konkuk University
2014
Korea University
2013
Cancer Clinic
2008
Seoul National University
2006
Kyung Hee University
2005
Dong-Eui University
1996
The goal of this study was to evaluate the therapeutic impact resection metastatic brain tumor cells infiltrating adjacent parenchyma.Between July 2001 and February 2007, 94 patients (67 males 27 females, with a mean age 55.0 +/-12.0 years) underwent single metastasis, followed by systemic chemotherapy or without radiotherapy. In 43 tumors located in noneloquent areas, authors performed microscopic total resections (MTRs) that included parenchyma, they pathologically confirmed during surgery...
Leptomeningeal carcinomatosis (LMC) is frequently associated with hydrocephalus, which quickly devastates the performance of patient. Cerebrospinal fluid (CSF) shunt a widely accepted treatment choice, but clinical outcomes in patients LMC are not well studied. This study aimed to examine efficacy CSF LMC. Seventy confirmed by cytology or magnetic resonance imaging (MRI) underwent ventriculoperitoneal (VP) lumboperitoneal (LP) surgery. We retrospectively analyzed characteristics patients,...
Abstract Background. The efficacy of ventriculolumbar perfusion (VLP) chemotherapy with methotrexate (MTX) was evaluated for treatment leptomeningeal carcinomatosis (LMC). Methods. primary outcome the response rate increased intracranial pressure (ICP), which available comparison from historical data on conventional intraventricular chemotherapy. Secondary endpoints were rates other LMC symptoms and overall survival patients. Artificial cerebrospinal fluid (CSF) premixed MTX continuously...
Objective. The objectives were to show the feasibility of a wireless microelectromechanical system inertial measurement unit (MEMS-IMU) assess time-domain characteristics cervical motion that are clinically useful evaluate spine movement. Methods. Cervical movements measured in 18 subjects with IMUs. All rotation data presented Euler angle system. Amount coupling motions was evaluated by calculating average ratio and maximum primary motion. Reliability is intraclass correlation coefficients...
Leptomeningeal metastases (LMs) are neoplasms that proliferate to membranes lining the brain and spinal cord. Intra-CSF methotrexate (MTX) chemotherapy is a prevalent treatment option. However, resultant long-term neurotoxicity can lead irreversible disseminated necrotizing leukoencephalopathy (DNL). This study aims determine incidence, characteristics, risk factors, outcomes of DNL following intra-CSF MTX for LM.
To define the maximum tolerated dose, toxicities, and pharmacokinetics of ventriculolumbar perfusion (VLP) chemotherapy for leptomeningeal carcinomatosis, according to different modes administration, rate, daily methotrexate (MTX) dose.For bolus injection modes, a designated MTX dose was given every 12 hours, 3 consecutive days, with artificial cerebrospinal fluid perfusion. The starting 40 mg mL/h perfusion, 24 20 mL/h, respectively. Although in continuous infusion premixed infused days....
A miniature fiber-optic dosimeter (FOD) system was fabricated using a plastic scintillating fiber, optical and multi-pixel photon counter to measure real-time entrance surface dose (ESD) during radiation diagnosis. Under varying exposure parameters of digital radiography (DR) system, we measured the light related ESD sensing probe FOD, which placed at center beam field on an anthropomorphic thorax phantom. Also, obtained DR images flat panel detector evaluate effects image artifacts...
Elevated cell counts and protein levels in cerebrospinal fluid (CSF) result from disease activity patients with leptomeningeal carcinomatosis (LMC). Previous studies evaluated the use of CSF profiles to monitor a treatment response or predict prognosis. vary, however, according sampling site patient's systemic condition. We compared lumbar ventricular collected before intraventricular chemotherapy for LMC association these patients' factors activity.CSF were retrospectively 228 who underwent...
Pulse diagnosis is important in oriental medicine. The purpose of this study explaining the mechanisms pulse with a cardiovascular simulator. simulator comprised generating part, vessel and measurement part. part was composed motor, slider-crank mechanism, piston pump. which aorta radial artery, fabricated silicon to implement wave propagation. parameters, such as depth, rate, shape, strength, were simulated. With changing mean pressure, floating sunken generated. change heart rate generated...
Blood pressure is an important factor in cardiovascular diseases, and it impossible to precisely reproduce the physical phenomenon of arteries by using conventional simulators with modeling blood vessels as air-filled chambers. The purpose this study was develop a simulator that replicates human arterial system. vessel part manufactured silicon which has similar stiffness tree structure. To evaluate validity developed simulator, flow were analyzed ascending aorta radial artery. Measured...
Intra-cerebrospinal fluid (CSF) chemotherapy for leptomeningeal metastasis (LM) can be delivered intraventricularly via an Ommaya reservoir. However, hydrocephalus associated with LM interfere chemotherapeutic drug distribution, and ventriculoperitoneal shunts prevent distribution to the extra-ventricular CSF space. This study examined feasibility of combining a lumboperitoneal (LP) shunt reservoir both control intracranial pressure allow intraventricular chemotherapy. We identified 16...
This research was undertaken to develop a cardiovascular simulator for use in the study of pulse diagnosis. The physical (i.e., wave transmission and reflection) physiological systolic diastolic pressure, mean pressure) characteristics radial were reproduced by our simulator. consisted an arterial component pulse-generating component. Computer simulation used simplify while maintaining elastic modulus artery size. To improve reflected characteristics, palmar arch incorporated within...
The conventional simulators used the expensive commercial artificial heart with a limited performance, and focused on replicating function. arterial pressure is key factor of cardiovascular disease. purpose this study to develop simulator wave. composed step motor, slider-crank mechanism, piston-cylinder, two check valves, elastic tube, reservoirs. With changes design parameters, functions were evaluated. shows good agreement characteristics system.
Objective : To evaluate the usefulness of a cranial implantable chemoport, H-port, as an alternative to Ommaya reservoir for intraventricular chemotherapy/cerebrospinal fluid (CSF) access in patients with leptomeningeal metastasis (LM).Methods One hundred fifty-two consecutive diagnosis LM and who underwent H-port installation between 2015 2021 were evaluated. Adverse events associated chemotherapy, rate increased intracranial pressure (ICP) control via port evaluated safety efficacy. These...
Objective Lumboperitoneal (LP) shunt has not been commonly used due to frequent over-drainage and malfunction. We adapted an LP with a valve reservoir or programmable for use in patients who needed avoid cranial surgery. compared the clinical results of ventriculoperitoneal (VP) shunt. Methods Among 188 installations, we selected 132 received first-time installation (108 VP 24 shunt) compare improvement, malfunction, over- under-drainage, infection rates along factors between two groups...