Background: Diabetes mellitus is a major public health problem in Morocco with more than 1.6 million cases of diabetes 2017 an expectation to rise over 2.7 2045. The aim this work provide ethnobotanical information on some the medicinal plants used by diabetic patients treat their illness region Fez-Meknes (Morocco).Methods: A semi-structured and simple questionnaire was carried out. total 422 interviews were conducted presented diagnosis Hassan II Hospital center Fez Morocco. data analyzed...

Background: Anacyclus pyrethrum (A. pyrethrum) is a wild species belonging to the family Asteraceae, which used in traditional medicines. Aim of study: This work was undertaken study chemical composition, analgesic, anti-inflammatory, and wound healing properties hydroalcoholic extracts different parts (roots, seeds, leaves, capitula) A. pyrethrum. Material Methods: The phytochemical analysis studied conducted by GC-MS. analgesic activity evaluated mice using acetic acid formaldehyde...

Pollen is a male flower gametophyte located in the anthers of stamens angiosperms and considerable source compounds with health protective potential. In present work, phytochemical screening was carried out as well analysis antioxidant antibacterial properties pollen extracts from Micromeria fruticosa, Achillea fragrantissima, Phoenix dactylifera growing wild Palestine. Phytochemical examined total flavonol, flavone phenolic content. The DPPH (1,2-Diphenyl-1-Picrylhydrazyl) FRAP (ferric...

In this work, two varieties of Anacyclus pyrethrum (L.) including var. and depressus (Ball) Maire were evaluated for their mineral chemical compositions, total phenolic flavonoid contents, antimicrobial antioxidant activities using hydroalcoholic extracts from different parts (leaves, capitula, roots, seeds). The phytochemical compositions carried out standard methods. activity was determined the DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2-azino-bis 3-ethylbenzothiazolin-6-sulfonic...

This work was conducted to study the chemical composition, antioxidant, antibacterial, and antifungal activities of essential oil hydrolat from Withania frutescens. The extracted by hydrodistillation. characterization performed using gas chromatography-mass spectrometry (GC/MS). antioxidant activity studied four different assays (DPPH, TAC, FRAP, β-carotene bleaching). antibacterial test carried out on multidrug-resistant bacteria including Gram-negative Gram-positive strains. Antifungal...

Flaxseed is an oilseed (45–50% oil on a dry-weight basis) crop. Its has demonstrated multiple health benefits and industrial applications. The goal of this research was to evaluate the antidiabetic anti-inflammatory potential free polyphenol fraction flax (Linum usitatissimum L.) seeds (PLU), based their use in traditional medicine. Mice with alloxan-induced diabetes were used study activity PLU vivo, oral administration 25 50 mg/kg over 28 days. Measurements body weight fasting blood...

Background: In Morocco, acute digestive system problems appear to be a famous daily ill which the most population deal with using medicinal plants. This work aims inventory plants used in region of Fez-Meknes.Methods: A survey was carried out by means semi-structured questionnaire. total 423 interviews (108 them are traditional health practitioners) were conducted. Botanical information about identified carefully collected. Data analyzed through relative frequency citation (RFC).Results: All...

Flavonoids are a class of natural chemicals with variable phenolic structures that have long been recognized for their health advantages, they recently attracted researchers’ attention treating diabetes and hyperglycemia. The goal this research is to develop novel antihyperglycemic formulation using combination three plant flavonoids: Linum usitatissimum L. seeds (FLU), Coriandrum sativum (FCS), Olea europaea var. sylvestris leaves (FOE) based on mixture design experiment approach which...

Withania frutescens (W. frutescens) is a medicinal plant widely used to treat several diseases. This work aims study phytochemical composition as well acute and subacute toxicity of W. hydroethanolic extract in mice. The was performed using gas chromatographic analysis. Acute studied vivo with oral administration single doses 400 mg/kg, 1000 2000 mg/kg for 14 days. Subacute the repeated mg/kg/day 28 Phytochemical analysis hydro-ethanolic confirmed presence interesting chemical compounds....

Depression and anxiety are major mental health problems in all parts of the world. These illnesses associated with a number risk factors, including oxidative stress. Psychotropic drugs chemical nature have demonstrated several side effects that elevated impact those illnesses. Faced this situation, natural products appear to be promising alternative. The aim study was evaluate anxiolytic antidepressant Petroselinum sativum polyphenols vivo, as well its correlated antioxidant properties...

Abstract Withania frutescens ( W. ) is a medicinal plant that largely used in the Morrocan pharmacopeia for disease treatment. This work was conducted to investigate chemical characterization, analgesic, anti-inflammatory, and healing activities of . The characterization extract done using HPLC; anti-inflammatory test performed with doses 300, 400 450 mg/kg, activity assessed two creams (extract 5% 10%). Phytochemical analysis revealed presence phenolic compounds. results were more...

Background . Withania frutescens. L ( W. frutescens ) is a perennial woody medicinal plant belonging to family Solanaceae largely used by the indigenous population Morocco for treatment of disease. Objective The purpose this study was investigate chemical composition, acute, and subacute toxicity W extract in mice. Materials Methods phytochemical composition determined using gas chromatograph (GC/MS). Acute carried out mice through oral administration single doses 500 mg/kg, 1000 2000 mg/kg...

Depression and anxiety are widespread illnesses whose consequences on patients’ social professional lives becoming ever more dangerous severe. The study’s objective is to explore the antidepressant-like anxiolytic activity of polyphenolic extract Carum carvi L. as well its antioxidant power they were recently associated. predictive antidepressant was evaluated using forced swimming tail suspension test in mice, a preclinical behavioral model widely used determine efficacy drugs. As for...

Background Flora growth is always influenced by the environmental conditions that surround plant. The Objective of Study present research work was undertaken to study response Withania frutescens (L.) Pauquy changes in investigating topographical, climatological, morphological, histological, and phytochemical aspects influencing plant’s growth. Materials Methods topography area described using Digital Terrain Model (DTM). bioclimatic carried out a climatological database (TerraClimate) used...

The present study is based on a multidisciplinary approach carried out for the first time Anacyclus pyrethrum var. and depressus, two varieties from endemic endangered medicinal species listed in IUCN red list, (L.) Link. Therefore, morphological, phytochemical, genetic characterisations were work. Morphological characterisation was established 23 qualitative quantitative characters describing vegetative floral parts. phytochemical compounds determined by UHPLC. Genetic of extracted DNA...

The study delves into the critical issue of declining Moroccan endemic plant species agro-sylva-pastoral and medicinal significance, impacted by various environmental degradation factors. With aim conserving rehabilitating these species, research focused on improving germination growth parameters Pistacia atlantica subsp. atantica whose seeds were carried from different area Middle Moulouya; Oled Ali Youssef; El Orjane Fritissa. In this study, nine treatments employed to overcome seed...

Episodes of drought that Morocco experienced in the years 1984–1986, 1993–1995, and 1997–2000 had repercussions were felt many later continue to pose serious problems for environmentalists, as some affected lands have become practically deserted. These acted on socio-economic conditions created severe constraints development country. This work was conducted study identify changes occurred vegetation cover Oued Lahdar watershed (Rif, Morocco) between 1984 2017 using Land Surface Temperature...

Natural products have offered a number of exciting approaches in cancer treatment over the years. In this study, we investigated prophylactic and therapeutic effects polyphenol-enriched fraction extracted from Myrtus communis (PEMC) on acute chronic leukemia. According to UHPLC-MSn, is rich flavonoids. Protective activity PEMC was assessed by evaluating antioxidant, anti-inflammatory, wound healing, hemolysis potential series vivo vitro assays, while approach consisted evaluation cytotoxic...

Our present study focuses on the evaluation of analgesic, anti-inflammatory and healing activity Withania frutescens L. The result has an inhibition percentage 78.87% ± 7.08 at 450 mg/kg 75.14% 6.39 400 89.75% 3.44 for diclofenac (1%). When applied locally, 10% cream inflammation 96.87% 5.85 76.14% 7.88 5% with 89.87 6.20 reference (Indomethacin). abdominal contractions rats treated root extract are significantly lower than those control group that received only physiological NaCl solution,...

Objective: In this study, we were interested in qualitative, quantitative phytochemical characterization and evaluation of the antioxidant capacity total extracts a plant from northern Morocco, species selected for study is Withania frutescens.
 Materials Methods: Analysis mineral elements by inductive coupling plasma-atomic absorption spectroscopy (ICP-AES), screening, polyphenol tannin assays, activity 1,2-diphenyl-β-picrylhydrazyl (DPPH) free radical scavenging method reducing...

Anacyclus pyrethrum (L.) has been used in traditional North African and Indian medicine for the treatment of several diseases such as cancer, rheumatism, epilepsy, diabetes, Alzheimer's disease. Despite its medical benefits, few studies have examined toxicity. The present study evaluated acute toxicity hydroethanolic extracts different parts (roots, seeds, leaves, capitula) two varieties A. (L.), namely, var. (L) depressus (Ball) Maire, mice.Acute was after oral administration at doses 300,...

The reproductive system is essential for the structuring and transmission of genetic diversity. Understanding biology threatened endemic species considered to be a crucial element implementation effective conservation strategies. Given lack information insufficient state knowledge on Anacyclus pyrethrum L., medicinal Morocco, we are first study two varieties L.: var. (L.) Link depressus (Ball.) Maire. was examined in detail by studying development inflorescence, phenology flowering, breeding...