Kidney disease is one of the most common health problems and kidney failure can be fatal. It disorders associated with extreme pain discomfort in patients. In developing countries, such as Morocco where socioeconomic sanitary conditions are precarious, medicinal plants considered primary source medication. present work an ethnobotanical survey was conducted a remote area North-Eastern we focused on (1) establishing record used traditionally by local people to treat diseases (2) correlate...

Atriplex halimus L., also known as Mediterranean saltbush, and locally "Lgtef", an halophytic shrub, is used extensively to treat a wide variety of ailments in Morocco. The present study was undertaken determine the antioxidant activity cytotoxicity ethanolic extract A. leaves (AHEE). We first determined phytochemical composition AHEE using liquid chromatography (LC)-tandem mass spectrometry (MS/MS) technique. evaluated different methods including DPPH scavenging capacity, β-carotene...

The botanical species Ceratonia siliqua L., commonly referred to as the Carob tree, and locally "L'Kharrûb", holds significance an agro-sylvo-pastoral species, is traditionally utilized in Morocco for treating a variety of ailments. This current investigation aims ascertain antioxidant, antimicrobial, cytotoxic properties ethanolic extract C. leaves (CSEE). Initially, we analyzed chemical composition CSEE through high-performance liquid chromatography with Diode-Array Detection (HPLC-DAD)....

Pollen is a male flower gametophyte located in the anthers of stamens angiosperms and considerable source compounds with health protective potential. In present work, phytochemical screening was carried out as well analysis antioxidant antibacterial properties pollen extracts from Micromeria fruticosa, Achillea fragrantissima, Phoenix dactylifera growing wild Palestine. Phytochemical examined total flavonol, flavone phenolic content. The DPPH (1,2-Diphenyl-1-Picrylhydrazyl) FRAP (ferric...

The biological activities of propolis samples are the result many bioactive compounds present in propolis. aim study was to determine various chemical some selected collected from Palestine and Morocco by High-Performance Liquid Chromatography–Photodiode Array Detection (HPLC-PDA) method, as well antioxidant antibacterial this bee product. analysis HPLC-PDA shows cinnamic acid content Palestinian sample is higher compared that Moroccan results activity demonstrated an important free radical...

In this work, two varieties of Anacyclus pyrethrum (L.) including var. and depressus (Ball) Maire were evaluated for their mineral chemical compositions, total phenolic flavonoid contents, antimicrobial antioxidant activities using hydroalcoholic extracts from different parts (leaves, capitula, roots, seeds). The phytochemical compositions carried out standard methods. activity was determined the DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2-azino-bis 3-ethylbenzothiazolin-6-sulfonic...

Diabetes mellitus is a serious metabolic disease, which affects large number of populations in the world. Phytotherapy considered as most remedies used by Moroccan people to treat this pathology. Argania spinosa L. (SKEELS) seeds oils among products that are traditionally Morocco for anti-diabetic purposes. The aim study investigate effect roasted (Roil) and unroasted (UnRoil) Argan on α-glucosidase, α-amylase intestinal glucose absorption activities vitro vivo. antihyperglycemic was tested...

Origanum compactum Benth (O. compactum) is widely used traditionally in Morocco to treat a broad range of illnesses, including infectious diseases. The aim this study was evaluate the phytochemical composition, quality control, and antibacterial activity O. leaf flower essential oil. First, control on soil irrigation water performed determine whether there any risk heavy metals endangering human health or causing stress plants studied. Laboratory examination environmental researched species...

The objectives of this work were to determine the phytochemical composition and antioxidant, anti-diabetic, antibacterial, anti-inflammatory, anti-acetylcholinesterase properties Arbutus unedo L. Laurus nobilis EOs. antioxidant effects estimated using four complementary methods. In addition, anti-diabetic activity was assessed by targeting three carbohydrate-hydrolyzing enzymes, namely α-amylase, α-glucosidase, lipase. anti-inflammatory evaluated testing inhibitory potential both plants on...

Diabetes is a global health concern with significant implications for individuals and healthcare systems. Finding effective safe antidiabetic agents crucial the management of this chronic disease. Natural products have emerged as potential alternatives to allopathic drugs, offering vast source bioactive compounds. In study, we conducted an assessment Origanum compactum essential oil, employing two-pronged approach, i.e., experimental investigation computational docking analysis. The results...

Many medicinal plants around the world are used for therapeutic purposes against several diseases, including diabetes mellitus. Due to their composition of natural substances that effective and do not represent side effects users, unlike synthetic drugs, in this study, we investigated inhibitory effect Caralluma europaea (CE) on α-glucosidase activity vitro; then kinetics enzyme were studied with increasing concentrations sucrose order determine inhibition type enzyme. In addition, was...

Objective: To assess the antidiabetic effect of Opuntia dillenii seed oil on rats with diabetes mellitus.Methods: A rat model was established by intraperitoneal injection 50 mg/kg streptozotocin. Thirty albino Wistar were divided into five groups: diabetic control group and normal treated only distilled water, two groups received 1 2 mL/kg per day, respectively, for 30 days one glibenclamide. In addition, blood glucose determined weekly. Body weight, average daily food, water intake urinary...

Opuntia dillenii (Ker-Gawl.) Haw. is a medicinal plant that widely used by the Moroccan population to treat many diseases, thanks its richness in bioactive molecules. This study aims evaluate total phenolic content and antioxidant, antihyperlipidemic, antidiabetogenic activities of O. seeds oil (ODSO), vivo. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging assay Folin–Ciocalteu method were applied this determine antioxidant activity ODSO, respectively. antihyperlipidemic effect ODSO (2...

The present study aims to evaluate the hepatoprotective activity of stem aqueous extract Caralluma europaea (AECe) on carbon tetrachloride- (CCl4-) induced hepatic damage in Wistar rats. animals were daily treated with C. at a dose 250 mg/kg body weight for 14 days. CCl4 was injected (1 ml/kg, i.p.) two times, 7th and 14th At end experimental period, all rats anesthetized collect blood assessment biochemical parameters then sacrificed liver weighing. Hepatotoxicity evaluated by measuring...

Opuntia dillenii Ker Gawl. is one of the medicinal plants used for prevention and treatment diabetes mellitus (DM) in Morocco. This study aims to investigate antihyperglycemic effect seed oil (ODSO), its mechanism action, any hypoglycemic risk toxic effects. The was assessed using OGTT test normal streptozotocin (STZ)-diabetic rats. mechanisms action were explored by studying ODSO on intestinal absorption d-glucose situ single-pass perfusion technique. An Ussing chamber explore effects...

Objective: To investigate the hepatoprotective effect of Opuntia dillenii seed oil (ODSO) on CCl4 provoked liver injury in rat. Methods: Animals were treated orally with ODSO at a concentration 2 mL/kg, once daily for one week before first intraperitoneal injection CCl4, and thereafter administration was continued 7 days until introduction second CCl4. Fourteen hours after last dose rats sacrificed, relative weight, weight gain, alkaline phosphatase, aspartate amino transferase, alanine...

<p class="Default">In Morocco, Raphanus sativus is a widespread traditional medicinal plant used to treat various kidney diseases such as nephropathy.</p><p class="Mabstract"><strong>Objective</strong>:<strong> </strong>The present study aims evaluate the protective effect of <em>R. </em>aqueous extract against gentamicin-induced acute nephrotoxicity in rats.</p><p class="Mabstract"><strong>Methods</strong>: Rats...

Thymelaea microphylla Coss. et Dur (T. microphylla), a medicinal herb that grows in arid and desert pastures, has been traditionally utilized by Moroccans to treat many diseases, including kidney failure. This study aims evaluate the nephroprotective effect against gentamicin-induced nephrotoxicity (GM), thus antioxidant activity of an aqueous extract rich flavonoids from aerial part T. (APTM). The APTM was assessed using 2-2-diphenyl-1-picrylhydrazyl (DPPH) scavenging test β-carotene...

The objective of this work is to explore the phytochemical profile Mentha piperita essential oils (MPEO) collected from two different Moroccan regions using gas chromatography-mass spectrophotometer (GC-MS) and investigate their antioxidant, anti-inflammatory, antidiabetic and, antimicrobial effects in vivo vitro assays. chemical constituent MPEO Azrou zone dominated by carvone (70.25%), while Ouazzane rich Menthol (43.32%) Menthone (29.4%). Ouezzane showed higher antioxidant activity than...

Background: This is the first ethnobotanical study focused on medicinal plants traditionally recommended by traditional healers (THs) of Eastern Morocco. In this work, we documented THs and highlighted value importance specialist healers. Methods: A quali-quantitative method has been performed, snowball sampling structured interviews were used to evaluate plant knowledge in area. Species identification was performed verified from African Plant Database List. Two Relative Cultural Importance...

Caralluma europaea (Guss.) N.E.Br. (C. europaea), is a medicinal plant used traditionally to treat diabetes mellitus (DM) in Morocco. This study aimed investigate the vitro antioxidant properties, glucose diffusion effects, α-amylase inhibitory activity, and pancreatic protective effects of C. experimental alloxan-induced mice. Total phenolic contents were determined by Folin-Ciocalteu colorimetric method, total flavonoid measured aluminum chloride assay, tannins employing vanillin method....

The purposes of this investigatory study were to determine the chemical composition essential oils (EOs) Origanum compactum from two Moroccan regions (Boulemane and Taounate), as well evaluation their biological effects. Determining EOs’ was performed by a gas chromatography–mass spectrophotometer (GC-MS). antioxidant activity EOs evaluated using free radical scavenging ability (DPPH method), fluorescence recovery after photobleaching (FRAP), lipid peroxidation inhibition assays....