Abstract The nutrient contents of Raphanus sativus L. (white radish) leaves (RSLs) and roots are known to have promising vital effects. We comparatively investigated the R. grown in Saudi Arabia estimate total phenol flavonoid using standard colorimetric methods. antioxidant activity RSLs (RSRs) were measured by 2,2′-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) 1,1-diphenyl-2-picrylhydrazyl (DPPH) assays. Both extracts’ cytotoxic was assessed MTT assay against several human cancer...

Abstract Background Esophageal squamous cell carcinoma (ESCC) has a poor prognosis and is one of the deadliest gastrointestinal malignancies. Despite numerous transcriptomics studies to understand its molecular basis, impact population-specific differences on this disease remains unexplored. Aims This study aimed investigate in gene expression patterns among ESCC samples obtained from six distinct global populations, identify differentially expressed genes (DEGs) their associated pathways,...

A nanocomposite composed of α-Fe2O3/g-C3N4 is synthesized using a modified ultrasonication approach, which engineered robust interfacial contact in the system. Phase formation and morphological features are confirmed via XRD electron-microscopy techniques. XPS revealed native oxidation states elements chemisorption-mediated interactions This developed composite produced hydrogen at rate 1494 μmolg−1 h−1, around 6.6 times higher than g-C3N4 The observed enhancement attributed to Z-scheme...

Datura innoxia is an important species of Solanaceae family with several purposes in folk medicine. This study intends to explore the cytotoxic effect D. on various cancer cell proliferation. ethanolic extract’s progression cycle and induction apoptosis were investigated by flow cytometry. Further, real-time PCR was employed confirm initiation. In addition, active phytochemicals identified gas chromatography–mass spectroscopy (GC-MS). The viability revealed that extract demonstrated potent...

Purpose: The knowledge of genetics among medical students was assessed to identify and analyze gaps that serve as bases for the revision current curriculum (Bachelor Medicine, Bachelor Surgery) MBBS Program College Medicine at Princess Nourah bint Abdulrahman University (PNU). Methods: A 65-item multiple-choice (MCQs) test in Genetics administered 71 second fourth-year assess their Genetics. MCQs were validated tested reliability. Self-assessment students' also determined by asking them...

Thymelaea microphylla Coss. et Dur (T. microphylla), a medicinal herb that grows in arid and desert pastures, has been traditionally utilized by Moroccans to treat many diseases, including kidney failure. This study aims evaluate the nephroprotective effect against gentamicin-induced nephrotoxicity (GM), thus antioxidant activity of an aqueous extract rich flavonoids from aerial part T. (APTM). The APTM was assessed using 2-2-diphenyl-1-picrylhydrazyl (DPPH) scavenging test β-carotene...

Background: This is the first ethnobotanical study focused on medicinal plants traditionally recommended by traditional healers (THs) of Eastern Morocco. In this work, we documented THs and highlighted value importance specialist healers. Methods: A quali-quantitative method has been performed, snowball sampling structured interviews were used to evaluate plant knowledge in area. Species identification was performed verified from African Plant Database List. Two Relative Cultural Importance...

COVID-19 infection has a spectrum of variable clinical severity between populations because their characteristic demographic features, co-morbidities, and immune system reactions. This pandemic tested the healthcare system's preparedness, which depends on predictors factors related to duration hospital stays. Therefore, we carried out single-center, retrospective cohort study in tertiary academic investigate these features severe disease different that affect stay. We utilized medical...

Collaboration between physicians and nurses is essential to healthcare delivery associated with high-quality patient care, greater satisfaction, better health outcomes. Hence, it imperative that doctors have a particular set of interprofessional collaboration skills. This descriptive cross-sectional study assessed how medical students in the pre-clinical clinical years perceived attitudes toward hospital setting. The Jefferson Scale Attitude Physician–nurse (JSAPNC) was reverse-translated...

In the context of addressing climate change, it becomes essential to anticipate how will affect plant biodiversity and way plants adapt physiologically morphologically challenging environmental circumstances.To gain a comprehensive understanding adverse climatic conditions, we conducted year-long study with three distinct water stress levels: 25% (sample 1), 50% 2), 75% 3).The findings revealed general decrease in primary metabolites (including proteins, carbohydrates, dietary fiber, lipids,...

Abstract Objectives Present report evaluates the protective effect of geraniol on high fat diet (HFD) induced obesity in rats and also determines molecular mechanism it. Methods Rats were with administration HFD for four weeks 200 400 mg/kg p.o. was administered next week respective groups. Blood glucose oral tolerance test (OGTT), lipid profile estimated treated rats. Moreover, docking study performed to determine specific by targeting HMG-CoE A reductase (in silico). Results There...

This study investigated people’s knowledge of genetics, attitudes toward genetic testing, and views on consanguinity. cross-sectional utilized a validated questionnaire modified from published studies to collect data genetics about testing among 1008 respondents various Saudi Arabian regions. Using SPSS software version 26, were analyzed using t-test, ANOVA, multivariate analysis. p-values <0.05 considered statistically significant. About 59.9% the participants had sufficient around 50%...

We earlier emphasized in vivo the lavender plant’s (Lavandula officinalis Chaix.) anti-inflammatory and estrogenic activities described chemical compositions of its hydro-ethanolic (HE) extract. used LC-MS/MS GC-MS analyses to profile phytochemical composition HE extract assess analgesic wound-healing effects both polyphenolic (LOP) extracts silico. The activity was studied using two methods: acetic acid formalin injections mice. carried out over 25 days a burn model rats. In silico study,...

The acceptance of online courses by medical and dental students, especially during the coronavirus disease 2019 crisis, is substantial, as reported in various studies. However, unfavourable learning experiences students pandemic were also highlighted. As teaching-learning process returning to "new normal," it necessary identify domains implemented crisis that may be applied pre-clinical future.

The present study aims to explore the phytochemical constitution and biological activities of Cleome felina L.f. (Cleomaceae). C. (leaves, stem, root) extracts (acetone, methanol, water) were qualitatively assessed for presence. Methanolic leaves extract revealed more positive phyto-compounds among all extracts; further, methanolic was evaluated FTIR, EDX, GCMS, antimicrobial assay, acute toxicity, paracetamol-induced hepatoprotective activity in Wister albino rats. FTIR EDX analysis...

Breast cancer ranked the 2nd amongst all in terms of mortality worldwide. We evaluated anticancer, apoptotic activity and toxicity polyherbal formulation, HF8, prescribed by herbalist Saudi Arabia. HF8 was prepared mixing different proportion plants namely Rosmarinus officinalis. L, Vitis vinifera seeds, Cichorium intybus Trigonella foenum-graecum L Lavandula multifida L., Pistacia lentiscus resin, commiphora myrrha Viola odorata flower. The for its cytotoxicity using human breast...

Abstract Numerous compounds derived from natural sources such as microbes, plants, and insects have proven to be safe, efficacious, cost-effective therapeutics for human diseases. This study examined the bioactivities of propolis, a structural sealant antibacterial/antifungal agent produced by honey bees. Chinese propolis was extracted in methanol or hexane. Propolis significantly reduced numbers viable cancer cells when applied extract (IC 50 values μg/mL indicated cell line: MDA-MB-231,...

Collaboration Effort between Physicians and Nurses: A Feedback Tool for the Review of Hospitals Nanette P. Franco, Mary Anne W. Cordero, Anahi Penelope Munoz, Denise Nash Abstract growing body research affirms significance physician-nurse collaboration delivery aquality patient care better health outcomes. In this descriptive comparative study, difference in attitudes toward physicians nurses was compared. Data were obtained through distribution survey questionnaire which is an adaptation...

<ns4:p>This article was migrated. The marked as recommended. Background: It is currently acknowledged that developing the skills in self-assessment imperative for continuing learning of every physician. Objective : This study aimed to assess students' performance tutorial sessions a hybrid problem-based (PBL) curriculum conducted during pre-clinical years through self-and tutors assessment. Methods Sixty nine first year and eighty second students Bachelor Medicine Surgery (MBBS) Program at...

Abstract. Ereguero MG, Cordero MA, Dalayap R, Tabugo SR. 2022. Antifungal activity of selected sea cucumber species from Tukuran, Zamboanga del Sur, Mindanao, Philippines using modified SPOTi assay. Biodiversitas 23: 6049-6055. Marine organisms have become essential candidates for discovering novel compounds that can be medically and commercially important. They are believed to yield with unique chemical structures significant biological activities since they managed survive a milieu...

A series of 3-amino-2-ethoxycarbonyl pyrido[l,2-a]thieno[2,3-d]-4-pyrimidone 10-13 were prepared in order to investigate their cytotoxicity and antimalarial activities.Some the them showed a promising activity.The detailed synthesis, spectroscopic, computational biological data are described.

Abstract. Ereguero MG, Gelani C, Dalayap R, Cordero MA, Tabugo SR. 2023. Antibacterial and anti-inflammatory potential of three sea cucumber species from Tukuran, Zamboanga del Sur, Mindanao, Philippines. Biodiversitas 24: 2527-2535. The marine environment is a rich source antibacterial agents. This study investigated species' activity methanol: ethyl acetate crude extracts Holothuria scabra, Stichopus sp., atra were tested for their against gram-negative (Pseudomonas aeruginosa, Escherichia...

The current development was focused on environmentally friendly and cost-effective synthesis of silver nanoparticles (AgNPs). This investigation aims to synthesize AgNPs using Anchusa arvensis aqueous plant extract. characterization confirmed by means different techniques including, X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), Fourier Transform Infrared (FT-IR) Spectroscopy, UV-visible analysis. crystalline morphology is demonstrated diffraction, with mean crystallite...