A5100759012- Phytochemicals and Antioxidant Activities
- Nematode management and characterization studies
- Chromatography in Natural Products
- Legume Nitrogen Fixing Symbiosis
- Plant-Microbe Interactions and Immunity
- Fermentation and Sensory Analysis
- Catalytic C–H Functionalization Methods
- Aerogels and thermal insulation
- Immune Response and Inflammation
- Sulfur-Based Synthesis Techniques
- Tea Polyphenols and Effects
- Fungal Biology and Applications
- Catalytic Alkyne Reactions
- Food Quality and Safety Studies
- Plant Pathogenic Bacteria Studies
- Supercapacitor Materials and Fabrication
- Polysaccharides and Plant Cell Walls
- Chemical Synthesis and Reactions
- Plant Gene Expression Analysis
- Pigment Synthesis and Properties
- Plant Virus Research Studies
- Free Radicals and Antioxidants
- Polysaccharides Composition and Applications
- Liver Disease Diagnosis and Treatment
- Postharvest Quality and Shelf Life Management
State Ethnic Affairs Commission
2023-2025
Southwest Minzu University
2023-2025
Zhejiang Sci-Tech University
2023-2024
South China Botanical Garden
2023-2024
Shandong University of Traditional Chinese Medicine
2024
Weifang Chinese Medicine Hospital
2024
Tianjin Medical University
2024
Shenyang Pharmaceutical University
2015-2024
Guangdong Academy of Medical Sciences
2020-2024
Southern Medical University
2023-2024
Abstract Ischemic stroke represents a significant danger to human beings, especially the elderly. Interventions are only available remove clot, and mechanism of neuronal death during ischemic is still in debate. Ferroptosis increasingly appreciated as cell after ischemia various organs. Here we report that serine protease, thrombin, instigates ferroptotic signaling by promoting arachidonic acid mobilization subsequent esterification gene, acyl-CoA synthetase long-chain family member 4...
An important regulator of innate immunity, the protein complex Toll-like receptors 1 and 2 (TLR1/TLR2) provides an attractive target for treatment various immune disorders. The novel compound CU-CPT22 can compete with binding specific lipoprotein ligand to TLR1/TLR2 (see picture) high inhibitory activity specificity. Repression downstream signaling from TNF-α IL-1β was also observed. Detailed facts importance specialist readers are published as "Supporting Information". Such documents...
Soil acidification is a major problem in modern agricultural systems and an important factor affecting the soil microbial community health. However, little known about effect of on soil-borne plant diseases. We performed 4-year investigation South China to evaluate correlation between occurrence bacterial wilt. The results showed that average pH fields infected by wilt disease was much lower than non-disease fields. Moreover, proportion soils with 5.5 higher non-infected soils, this...
Application of soil amendments has been wildly used to increase pH and control bacterial wilt. However, little is known about causal shifts in the rhizosphere microbial community crops, especially when field naturally harbors disease wilt tobacco for many years due long-term continuous cropping acidification. In this study, biochar (CP), lime (LM), oyster shell powder (OS) no amendment additions (Control; CK) were assessed their abilities improve acidification, change composition communities...
Direct, economical, and green synthesis of deuterated α-amino phosphine oxides remains an elusive challenge in synthetic chemistry. Herein, we report a visible-light-driven umpolung strategy for synthesizing from isocyanide using 1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene as the photocatalyst D2O deuterium source. Moreover, streamlined sustainable methodology can be applied modification amino acids, natural products, drugs. The strong antiproliferative activity desired products...
With the rapid development of social economy, problems such as volatile organic compound (VOC) pollution and excessive consumption global petroleum resources have become increasingly prominent. People are beginning to realize that these not only affect ecological environment, but also hinder polymer material industry based on raw fossil materials. Therefore, modification application bio-based materials theoretical practical significance. In this study, a series vegetable oil-based acrylate...
Background and objectives The association of diabetic retinopathy (DR) macular oedema (DME) with renal function in southern Chinese patients diabetes is poorly understood. So we aimed to study the correlation between stage DR DME estimated glomerular filtration rate (eGFR) urine albumin-to-creatinine ratio (UACR), explore systemic risk factors for DME. Design setting This single-centre retrospective observational was conducted from December 2017 November 2018. Participants 413 type 2...
Bacterial wilt is accompanied by microbial communities shift and soil acidification. However, the relationship between changes of bacterial under influence different acidification levels has not been fully elucidated. Here, we analyzed abundance Ralstonia solanacearum, rhizosphere carbon metabolism at differently acidic (pH 6.45, pH 5.60, 5.35, 4.90 4.45) amendment treatment (CaO). The results indicated that both R. solanacearum incidence showed a significant trend first increasing then...
The palladium-catalyzed asymmetric carboamination reaction is one of the most significant transformations in organic chemistry. Herein, we report first alleneamination β,γ-unsaturated hydrazones with propargylic acetates. This protocol enables efficient installation various multisubstituted allene groups onto dihydropyrazoles good yields excellent enantioselectivities. chiral sulfinamide phosphine ligand Xu-5 exhibits highly stereoselective control this protocol. salient features include...
Abstract WRKY transcription factors are involved in plant defense against pathogens. No WRKYs have been reported to be resistance tobacco brown spot disease caused by Alternaria alternata. Here, we found that NaWRKY3 plays a critical role Nicotiana attenuata A. bound and regulated many genes, including: lipoxygenase 3, ACC synthase 1, oxidase three jasmonate- ethylene-biosynthetic genes; feruloyl-CoA 6ʹ-hydroxylase 1 (NaF6ʹH1), the biosynthetic gene for phytoalexins scopoletin scopolin;...
Bacterial wilt, caused by Ralstonia solanacearum, is a devastating disease resulting in tremendous losses of economic crops such as plants the Solanaceae. Recent studies showed that R. solanacearum spreading from lowlands to highlands China. We studied 97 Chinese strains were isolated four tobacco-growing zones over wide range elevations using phylotype specific multiplex polymerase chain reaction (Pmx-PCR) and phylogenetic relationships (egl mutS). The results all isolates belonged I, which...
Moringa oleifera leaves have been widely used for the treatment of inflammation, diabetes, high blood pressure, and other diseases, due to being rich in polyphenols. The main objective this work was largely separate polyphenols from using technique high-speed counter-current chromatography (HSCCC). phenolic composition first analyzed qualitatively quantitatively by UPLC-Q-Exactive Orbitrap/MS UPLC-QqQ/MS, respectively, indicating that quercetin kaempferol derivatives, acid apigenin are...
In this study, an effective method for preparation of bioactive galloylated procyanidin B2-3′-O-gallate (B2-3′-G) was first developed by incomplete depolymerization grape seed polymeric procyanidins (PPCs) using l-cysteine (Cys) in the presence citric acid. The structure–activity relationship B2-3′-G further evaluated vitro through establishing lipopolysaccharide (LPS)-induced inflammation RAW264.7 cells. results suggested that better protective effects against were attributed to its...
A chiral NHC-catalyzed [3 + 3] cycloaddition reaction of 3-aminobenzofurans with isatin-derived enals has been documented, furnishing 3,4′-piperidinoyl spirooxindoles bearing a quaternary stereocenter good yields and excellent enantioselectivities. Further gram-scale preparation synthetic transformation the cycloadducts to δ-amino acid derivative demonstrated practicality applicability this reaction.