A5055106184- Influenza Virus Research Studies
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Vaccine Coverage and Hesitancy
- Herpesvirus Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Infectious Encephalopathies and Encephalitis
- Bartonella species infections research
- Pediatric health and respiratory diseases
- Liver Disease and Transplantation
- SARS-CoV-2 and COVID-19 Research
- Vector-borne infectious diseases
- Acne and Rosacea Treatments and Effects
- Neonatal Respiratory Health Research
- Immune Response and Inflammation
- Abdominal vascular conditions and treatments
- Poxvirus research and outbreaks
- Eosinophilic Disorders and Syndromes
- Thermal Regulation in Medicine
- Child and Adolescent Health
- Rabies epidemiology and control
- Eosinophilic Esophagitis
- Renal and Vascular Pathologies
- Dermatology and Skin Diseases
Children's Hospital at Westmead
2012-2024
National Centre for Immunisation Research & Surveillance
2012-2024
The University of Sydney
2002-2024
Office of Adolescent Health
2023
Sydney Children's Hospital
2011-2020
Lismore Base Hospital
2002
There are few longitudinal studies of seasonal influenza-associated neurological disease (IAND) and none from the Southern Hemisphere.We extracted prospectively acquired Australian surveillance data 2 nested within Paediatric Active Enhanced Disease Surveillance (PAEDS) network: Influenza Complications Alert Network (FluCAN) study Childhood Encephalitis (ACE) between 2013 2015. We described clinical features severity IAND in children, including encephalitis/encephalopathy (IAE). calculated...
Eosinophilic esophagitis (EE) is characterized by marked esophageal mucosal eosinophilia on histological examination. Although the clinical and features of EE are increasingly recognized, overlap symptoms findings with gastroesophageal reflux disease (GERD) can lead to diagnostic difficulty. In children we sought define frequency subepithelial fibrosis correlates this feature. The specificity finding in was obtained comparison a matched group GERD, ascertain its usefulness as aid...
Influenza causes a large burden of disease in children. Point-of-care testing (POCT) can rapidly diagnose influenza with the potential to reduce investigation and hospital admission rates, but information on its use an Australian setting is limited.Through retrospective review laboratory-confirmed cases presenting at paediatric emergency department (ED) 2009, we evaluated children diagnosed by POCT versus standard (direct fluorescent antibody, polymerase chain reaction or viral culture)...
SUMMARY Australia's National Immunisation Program (NIP) provides free influenza vaccination for children at high risk of severe influenza; a pilot-funded programme vaccine in all aged 6 months to <5 years one eight states, has seen poor impact, related recent safety concerns. This retrospective review examined hospitalizations <16 from three seasons (2011–2013) two paediatric hospitals on opposite sides the country. Comparisons this cohort were made with state-based data...
To examine the reported incidence and features of disseminated varicella zoster virus (VZV) infection following live attenuated herpes vaccine (ZVL: Zostavax, Merck) in immunocompromised people Australia.
Annual seasonal influenza epidemics cause substantial disease and economic burden worldwide. During the coronavirus 2019 (COVID-19) pandemic in 2020 2021, activity significantly declined. However, resurged Australia following relaxation of non-pharmaceutical interventions, with increased virus circulation early 2022 coinciding SARS-CoV-2 Omicron BA.2 variant wave. Together other respiratory diseases, these impacts on Australian population healthcare system have re-emphasised importance...
Aim Influenza causes a substantial burden in young children. Vaccine efficacy ( VE ) data are limited this age group. We examined trivalent influenza vaccine TIV and safety children attending childcare. Methods A double‐blind, randomised controlled trial aged 6 to <48 months was conducted with recruitment from Sydney childcare centres 2011. Children were receive two doses of or control hepatitis vaccine. Efficacy evaluated against polymerase chain reaction‐confirmed using parent‐collected...
Please cite this paper as: Khandaker et al. (2012) Comparing the use of, and considering need for, lumbar puncture in children with influenza or other respiratory virus infections. Influenza Other Respiratory Viruses DOI:10.1111/irv.12039. Background The clinical presentation of infancy may be similar to serious bacterial infection investigated invasive procedures like (LP), despite very limited evidence that occurs concomitantly meningitis, perhaps because diagnosis is often not established...
Comparing postvaccination fever rates in pediatric influenza vaccine clinical trials is difficult due to variability how reported. The impact of vaccine-related and antipyretic use on trivalent immunogenicity children also unclear.In this pilot study, we used individual-level data provided by GlaxoSmithKline from 3 versus comparator vaccine. We explored a primary study (NCT00764790), the largest trial involving young (6-35 months, n = 3317), further key findings 2 other (3-17 years,...
Live attenuated herpes zoster vaccine (Zostavax [CSL/Merck]) was included on the Australian National Immunisation Program from 1 November 2016 for adults aged 70 years, with a catch-up program 71-79 years. The aim of this study to assess knowledge general practitioners (GPs) regarding Zostavax.A national cross-sectional online survey distributed GPs by Healthed, private health education provider.Of 605 GPs, 502 responded (response rate 83%). Eighty-nine per cent were aware that Zostavax is...