Guilherme Sant’Anna

ORCID: 0000-0003-1633-3654
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About
Contact & Profiles
Research Areas
  • Neonatal Respiratory Health Research
  • Neuroscience of respiration and sleep
  • Infant Development and Preterm Care
  • Congenital Diaphragmatic Hernia Studies
  • Respiratory Support and Mechanisms
  • Neonatal and fetal brain pathology
  • Non-Invasive Vital Sign Monitoring
  • Cardiac Arrest and Resuscitation
  • Congenital Heart Disease Studies
  • Neonatal Health and Biochemistry
  • Heart Rate Variability and Autonomic Control
  • Pediatric Hepatobiliary Diseases and Treatments
  • Wireless Body Area Networks
  • Thermal Regulation in Medicine
  • Adipose Tissue and Metabolism
  • Infant Nutrition and Health
  • COVID-19 Impact on Reproduction
  • Healthcare Technology and Patient Monitoring
  • Birth, Development, and Health
  • Maternal and Neonatal Healthcare
  • COVID-19 and healthcare impacts
  • Neonatal and Maternal Infections
  • Airway Management and Intubation Techniques
  • Emergency and Acute Care Studies
  • Infant Health and Development

McGill University
2015-2024

McGill University Health Centre
2014-2024

Montreal Children's Hospital
2015-2024

Universidade Federal Fluminense
2024

Pediatrics and Genetics
2021

McMaster University
2007-2009

Mahidol University
2008

Siriraj Hospital
2008

Fundação Oswaldo Cruz
2007

McMaster Children's Hospital
2007

<h3>Objective</h3> To determine periextubation practices in extremely preterm infants (&lt;28 weeks gestation). <h3>Design</h3> A survey consisting of 13 questions related to weaning from mechanical ventilation, assessment extubation readiness and postextubation respiratory support was developed sent clinical directors level III NICUs Australia, Canada, Ireland, New Zealand USA. descriptive analysis the results performed. <h3>Results</h3> 112/162 (69%) units responded; 36% reported having a...

10.1136/archdischild-2015-308549 article EN Archives of Disease in Childhood Fetal & Neonatal 2015-06-10

The purpose of this work was to evaluate the impact implementation a ventilation protocol driven by registered respiratory therapists on outcomes premature infants with birth weight < or =1250 g.A therapist developed multidisciplinary group and implemented in our unit July 2004. A retrospective review 301 inborn g who were mechanically ventilated performed. Ninety-three before (before), 109 first year (after 1) 99 during second 2) after implementation. Data collected predefined form.The...

10.1542/peds.2008-1647 article EN PEDIATRICS 2009-04-21

&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; Mechanical ventilation (MV) is associated with changes in autonomic nervous system activity preterm infants, which can be assessed by measurements of heart rate variability (HRV). Decreased HRV has been described adults undergoing disconnection from MV; such information not available infants. &lt;b&gt;&lt;i&gt;Objective:&lt;/i&gt;&lt;/b&gt; To compare differences between infants successfully extubated and those who failed, to evaluate the...

10.1159/000347101 article EN Neonatology 2013-01-01

<h3>Importance</h3> Spontaneous breathing trials (SBTs) are used to determine extubation readiness in extremely preterm neonates (gestational age ≤28 weeks), but these rely on empirical combinations of clinical events during endotracheal continuous positive airway pressure (ET-CPAP). <h3>Objectives</h3> To describe ET-CPAP and assess accuracy comprehensive event predicting successful compared with judgment alone. <h3>Design, Setting, Participants</h3> This multicenter diagnostic study data...

10.1001/jamapediatrics.2019.4868 article EN JAMA Pediatrics 2019-12-20

Background A spontaneous breathing trial (SBT) has been used to guide suitability of extubation in VLBW infants. Respiratory variability (RV) assess readiness adults but was never investigated preterms. The combination a SBT and RV may further improve prediction successful extubation. Study design Using data previously collected during the SBT, following respiratory variables were analysed: inspiratory time (T I ), expiratory E T /total breath time, tidal volume (V ) mean flow /T )....

10.1136/fetalneonatal-2011-301340 article EN Archives of Disease in Childhood Fetal & Neonatal 2012-05-03

Extremely preterm infants (≤ 28 weeks gestation) commonly require endotracheal intubation and mechanical ventilation (MV) to maintain adequate oxygenation gas exchange. Given that MV is independently associated with important adverse outcomes, efforts should be made limit its duration. However, current methods for determining extubation readiness are inaccurate a significant number of fail reintubation, an intervention may increased morbidities. A variety objective measures have been...

10.1186/s12887-017-0911-z article EN cc-by BMC Pediatrics 2017-07-17

Decreases below the target temperature were noted among neonates undergoing cooling in Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network Trial whole body hypothermia for neonatal hypoxic-ischemic encephalopathy.To examine profile impact on outcome ≥ 36 wk gestation randomized at ≤ 6 hrs age targeting an esophageal 33.5°C 72 hrs.Infants with intermittent temperatures recorded <32.0°C during induction maintenance compared to all other...

10.1097/pcc.0b013e31821926bc article EN Pediatric Critical Care Medicine 2011-04-15

Neonatal heart rate variability (HRV) is widely used as a research tool. However, HRV calculation methods are highly variable making it difficult for comparisons between studies.To describe the different types of investigations where neonatal was used, study characteristics, and analyses performed.Human neonates ≤1 month corrected age.A protocol search strategy literature developed in collaboration with McGill University Health Center's librarians articles were obtained from searches Biosis,...

10.1136/bmjopen-2021-055209 article EN cc-by-nc BMJ Open 2021-12-01

A multidisciplinary comprehensive protocol to use bubble continuous positive airway pressure (bCPAP) as the primary respiratory support in delivery room (DR) and NICU was introduced. With this study, we aimed assess association of change with outcomes over time.

10.1542/peds.2023-065373 article EN PEDIATRICS 2024-06-18
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