A5075759398- Mosquito-borne diseases and control
- HIV Research and Treatment
- Virus-based gene therapy research
- RNA regulation and disease
- Malaria Research and Control
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Vectors
- Pneumonia and Respiratory Infections
- COVID-19 and Mental Health
- COVID-19 Clinical Research Studies
- RNA modifications and cancer
- Sepsis Diagnosis and Treatment
- Animal Virus Infections Studies
- Evolution and Genetic Dynamics
- Autophagy in Disease and Therapy
- COVID-19 epidemiological studies
- Insect Pest Control Strategies
- Travel-related health issues
- Peroxisome Proliferator-Activated Receptors
- Climate Change and Health Impacts
- Diabetes and associated disorders
- Diet, Metabolism, and Disease
- Influenza Virus Research Studies
- Medicinal Plants and Bioactive Compounds
Universidad Nacional Autónoma de México
2020-2025
Center for Research and Advanced Studies of the National Polytechnic Institute
2014-2019
Instituto Politécnico Nacional
2018-2019
National Institute of Genomic Medicine
2015
Dengue is the most common mosquito-borne viral disease in humans. Changes of lipid-related metabolites endoplasmic reticulum dengue virus (DENV) infected cells have been associated with replicative complexes formation. Previously, we reported that DENV infection inhibits HMGCR phosphorylation generating a cholesterol-enriched cellular environment order to favor replication. In this work, using enzymatic assays, ELISA, and WB found significant higher activity cells, inactivation AMPK. AMPK...
The study aimed to describe the characteristics and risk factors associated with disease severity across six waves of COVID-19 in pediatric population Mexico. A cohort was conducted using data from Mexican Ministry Health, covering period March 2020 2023. dataset included patients under 18 years age confirmed SARS-CoV-2 infection. Univariate, bivariate, logistic regression analyses were performed determine demographic clinical characteristics, mortality waves, group distributions. Of total...
A regulatory subunit of a voltage-gated calcium channel translocates to the nucleus promote an antiviral response.
SARS-CoV-2 continues to have a high rate of contagion worldwide. The new variant concern, Omicron, has mutations that decrease the effectiveness vaccines and evade antibodies from previous infections resulting in fourth wave pandemic. It was identified Mexico December 2021.The Traveler's Preventive Care Clinic Faculty Medicine UNAM at City International Airport performed rapid antigen PCR SARS CoV2 tests since January 2021 comply with travel requirements. Demographic clinical characteristics...
Human rhinovirus (HRV), traditionally recognized as the primary etiological agent of common cold, has become second most important viral in bronchopulmonary conditions, such pneumonia and asthma exacerbations. During COVID-19 pandemic, several viruses exhibited changes their epidemiological behavior. This study aims to evaluate clinical characteristics children with HRV before during pandemic Mexico.
The aim of the present study was to determine association between extracellular heat shock protein (eHsp70) levels with mortality in adult patients septic shock, as well eHsp70 and APACHE II SOFA scores, cytokines inflammatory response. an observational, longitudinal, prospective, cohort study. Adult admitted intensive care unit (ICU) were included study; measured sera by ELISA, scores determined upon admission every two days until death or discharge for improvement. pro‑inflammatory at...
Abstract Background The COVID-19 pandemic represents one of the greatest public health crises in this century . Since beginning there were reports persistence symptoms after an average recovery period 2-5 weeks. Long-COVID syndrome was defined as a continuation or onset within 3 months initial infection, lasting for at least 2 with no explanation. There are few studies focused on neurological long COVID ambulatory patients who suffered mild disease. Methods We conducted prospective cohort...
Abstract Despite the importance of Dengue virus (DENV) infection in human health, there is not a fully effective vaccine or antiviral treatment against infection. Since lipids such as cholesterol are required during DENV infection, its uptake and synthesis increased infected cells. Ezetimibe an FDA-approved drug that reduces humans by inhibiting endocytosis through Niemman-Pick C1-Like 1 (NPC1L1) receptor, expressed on membrane enterocytes hepatocytes. Our results indicate increase amount...