A5079166146- African Botany and Ecology Studies
- Phytochemicals and Antioxidant Activities
- Traditional and Medicinal Uses of Annonaceae
- Hibiscus Plant Research Studies
- X-ray Diffraction in Crystallography
- Essential Oils and Antimicrobial Activity
- Heavy Metals in Plants
- Crystallization and Solubility Studies
- Agriculture, Plant Science, Crop Management
- Natural Antidiabetic Agents Studies
- SARS-CoV-2 and COVID-19 Research
- Thyroid Cancer Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Pesticide Exposure and Toxicity
- Biosensors and Analytical Detection
- Innovative Microfluidic and Catalytic Techniques Innovation
- Analytical chemistry methods development
- Neonatal Health and Biochemistry
- Mycotoxins in Agriculture and Food
- Analytical Chemistry and Sensors
- Seed and Plant Biochemistry
- Phytochemical and Pharmacological Studies
- Adsorption, diffusion, and thermodynamic properties of materials
- Ziziphus Jujuba Studies and Applications
- thermodynamics and calorimetric analyses
Institut Pasteur de Dakar
2025
Cheikh Anta Diop University
2015-2024
Laboratoire de Chimie
2022
Laboratoire de Chimie Organique
2016-2018
Numerous studies elucidated the kinetics of humoral immune response post-SARS-CoV-2 infection. However, in sub-Saharan Africa, evolution SARS-CoV-2 IgG antibody responses and their interaction with pre-existing seasonal human coronavirus (HCoVs: OC43, 229E, NL63, HKU1) immunity remain underexplored. A prospective cohort study was conducted Senegal during first year COVID-19 pandemic (March to December 2020). total 204 patients laboratory-confirmed were included. Patients classified as...
L’objectif de la présente étude était d’évaluer l’activité antioxydante des extraits feuilles Vitex doniana par spectrophotométrie en utilisant les méthodes piégeage radicaux libres 2,2-diphényl-1- picryl-hydrazyle (DPPH•) et acide 2,2’-azino-bis-(3-éthylbenzothiazoline-6-sulfonique) (ABTS+•). Une extraction éthanolique a été effectuée au Soxhlet. L’extrait sec recueilli redissout dans l’eau puis fractionné successivement l’hexane, du dichlorométhane l’acétate d’éthyle. Les propriétés...
Pesticides are extensively used by farmers in the Niayes zone of Dakar regardless good agricultural practices as evidenced many authors. Some them were either not registered or banned for use Senegal. This situation raises concerns about environmental impact and human health risks. work aimed to assess presence 21 pesticide molecules selected through a survey soil groundwater. For that purpose, 119 80 groundwater samples collected at four different sites analyzed chromatographic methods....
The aim of this study was to recover metals from the positive electrode material for recycling in lithium-ion batteries. It focused on research optimize hydrometallurgical pretreatment process cathode materials Li-ion batteries by varying parameters such as NaOH concentration, ratio solvent volume mass test sample (liquid-solid (L/S)) and reaction time. Thus, used collected a local market (Colobane, Senegal), cathodic dried an oven at 50°C 24 hours, submitted alkaline leaching with 2, 3 or...
Les plantes traditionnelles présentent généralement de nombreuses propriétés thérapeutiques. L’objectif la présente étude consistait à évaluer l’activité antioxydante des extraits feuilles Aphania senegalensis et Saba par spectrophotométrie moléculaire au moyen méthodes piégeage radicaux libres 2,2-diphényl-1-picryl-hydrazyle (DPPH•) acide 2,2’-azino-bis-(3-éthylbenzothiazoline-6- sulfonique) (ABTS+•). Une extraction éthanolique ces deux a été effectuée Soxhlet. secs, redissouts dans l’eau,...
Les plantes médicinales telles que Moringa oleifera, présentent en général de nombreuses vertus thérapeutiques. L'objectif cette étude était d'évaluer l'activité antioxydante des extraits feuilles oleifera par la méthode piégeage radicaux libres 2,2-diphényl-1- picryl-hydrazyle (DPPH•). Une extraction éthanolique a été effectuée et l'extrait sec obtenu ensuite fractionné séparation liquide-liquide avec solvants polaires (eau distillée acétate d'éthyle) apolaires (dichlorométhane). L'extrait...
La drépanocytose est une hémoglobinopathie largement répandue chez les populations africaines noires. Actuellement, très peu de traitements conventionnels existent sur le marché, d’où recours à la médecine traditionnelle. Maytenus senegalensis plante prescrite par tradipraticiens dans prise en charge drépanocytose. L’activité antifalcémiante des extraits poudre racines a été étudiée ce travail. Après obtention l’extrait hexanique extraction l’aide d’un Soxhlet, marc macéré l’acétate d’éthyle...
This study aimed at validating an analytical method, using the accuracy profile approach, for assay of chlorphenamine maleate by capillary electrophoresis. The validation was done concentrations ranging between 75% and 125% target concentration 600 mg/ml. Validation standards were prepared separately in triplicate each series. Studied criteria selectivity, linearity, trueness, precision (repeatability intermediate precision), limits detection quantification. method selective, with recoveries...
Hibiscus sabdariffa also known as Roselle is a shrub generally measuring between one and two meters in height. After flowering, white or red calyxes appear, depending on the variety. These are highly prized by African populations for production of drinking juice. Thus, this work was initiated to study thermal effects physico-chemical parameters juice obtained. The pH determined using meter, conductivity meter. Polyphenols were quantified ferric chloride reaction Folin-Ciocalteu's reagent....
Methylene blue (MB) is a phenothiazine derivative used in microbiology, surgery, diagnostics and as sensitizer the photo-oxidation of organic pollutants. These numerous uses methylene could lead to its accumulation wastewater, causing harmful effects on environment living beings. To combat these effects, wastewater treatment processes, particularly physicochemical, were implemented. Adsorption techniques are find new natural, biodegradable inexpensive adsorbents treat colored waste from...
We report the synthesis and structures of two transition-metal complexes involving 2-(2-hydroxyphenyl)benzimidazole (2hpbi – a ligand interest for its photoluminescent applications), with cobalt, namely, bis[μ-2-(1 H -1,3-benzodiazol-2-yl)phenolato]bis[ethanol(thiocyanato)cobalt(II)], [Co 2 (C 13 9 N O) (NCS) 6 ], ( 1 ), manganese, -1,3-benzodiazol-2-yl)phenolato]bis{[2-(1 -1,3-benzodiazol-2-yl)phenolato](thiocyanato)manganese(III)} dihydrate, [Mn 4 ]·2H O, ). These are recent examples...
This study determined mineral value and antioxidant activity of Senegal fruits for contributing to improving healthy diet preventing some chronic diseases. Mineral element contents Dialium guineense, Landolphia heudelotti, Mangifera indica, Cyperus esculentus Saba senegalensis, which are widely available consumed, were studied. The results by ICP-OES spectrophotometry after acid mineralization showed highest levels (per 100 g fruits), calcium (158 mg), potassium (1018 magnesium (532 zinc (26...
Recommended supplementation of salt with iodine and requirements for controlling iodised result in the necessary validation titrimetric method used quantification this micronutrient. This study presents through accuracy profile approach over range 12–36 ppm. Several performance criteria were evaluated: linearity, repeatability, intermediate precision, trueness accuracy. The limits detection also determined. recoveries ranged from 98.1 % to 100.2 relative standard deviations between 0.7 2.2...
Detarium senegalense, microcarpum et Piliostigma reticulatum sont trois plantes de la flore sénégalaise, utilisées en médecine traditionnelle pour prise charge maladies infectieuses. Cette étude visait à déterminer in vitro l’activité antimicrobienne d’extraits fractions feuilles ces sur différentes souches (Escherichia coli, Klebsiella oxytoca, Pseudomonas aeruginosa, Enterococus faecalis, Staphylococcus aureus Candida albicans). Les méthodes diffusion milieu solide dilution liquide ont été...
In Senegal, artisanal vegetable oils trade is developing and <i>Balanites aegyptiaca </i>(desert date) as well <i>Sesamum indicum </i>(sesame) are popular vegetal species. Present study focused on obtained from these two plants seeds. These have various applications such for dietary cosmetic purposes. Sampling carried out in Dakar region allowed collection of five oil samples each specie, mainly different districts shops or craft fairs. Their peroxide, acid, iodine saponification values...
Aflatoxin B1 is a mycotoxin that can contaminate wide feedstuffs variety. Ingestion of contaminated feed by poultry lead to impaired health and zootechnical performances but also human diet safety problem related residues presence in animal origin products. contamination samples marketed Dakar city peri-urban areas (Gorom, Sangalkam) was studied. A total 15 were collected from markets as well farms Gorom Sangalkam areas. quantification performed high performance liquid chromatography...
Oxidative stress, caused by reactive oxygen species, is known to cause oxidation of biomolecules, leading cell damage and important enzymes, resulting in an unstable pathophysiological state. The antioxidant capacity leaves, stems, roots Cordyla pinnata was determined measuring the inhibition absorbance 2,2-diphenyl-1-picryl-hydrazyl (DPPH) 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals spectrophotometry. polyphenol contents were with same technique. mineral...
This study is part of the biological investigation chemical library molecules already described by Laboratory Organic Chemistry and Therapeutic University Bordeaux. The main objective was to explore contribution a thienyl moiety attached pyrimidinone nucleus, in expression an antimicrobial activity.
 structural modifications mainly concerned conservation or not benzo fragment thienyl, saturation position-1,2 ring, substitution on N-benzyl with more less lipophilic units, modification...