A5058501619- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Cancer therapeutics and mechanisms
- Lung Cancer Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Gastrointestinal disorders and treatments
- Cancer Genomics and Diagnostics
- Colorectal and Anal Carcinomas
- Radiomics and Machine Learning in Medical Imaging
- Esophageal and GI Pathology
- Cancer, Lipids, and Metabolism
- Medical Imaging and Pathology Studies
- Peptidase Inhibition and Analysis
- Medical Imaging Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Inflammatory Biomarkers in Disease Prognosis
- Foreign Body Medical Cases
Tamedia (Switzerland)
2025
JGC (Japan)
2024
Universidade de São Paulo
2015-2021
Hospital Alemão Oswaldo Cruz
2021
Universidade Brasil
2020
National Kyushu Medical Center
2017-2019
Clinical Research Institute
2019
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2005-2018
Hiratsuka Kyosai Hospital
2017
Shizuoka Cancer Center
2009-2016
In many countries, gastric cancer is not diagnosed until an advanced stage. An Internet-based e-learning system to improve the ability of endoscopists diagnose at early stage was developed and evaluated for its effectiveness.The study designed as a randomized controlled trial. After receiving pre-test, participants were randomly allocated either or non-e-learning group. Only those in group gained access system. Two months after both groups received post-test. The primary endpoint difference...
Objective This study aimed to evaluate the feasibility and clinicopathological characteristics of early gastric esophageal cancers treated with endoscopic submucosal dissection (ESD) at five centers in Brazil. Methods Five Brazil reported their initial experience ESD. The cases had already been collected by each center before pooled analysis. Results Were resected 62 lesions; 52(83,8%) lesions were well-differentiated adenocarcinoma, 31(50%) from antrum, 24 (38.7%) type IIa. 51 (82.2%)...
BackgroundPemetrexed in combination with cisplatin (Pem/Cis) is used globally for the treatment of malignant pleural mesothelioma (MPM). This Phase I/II study was conducted to determine recommended dose (RD) (Phase I) Pem/Cis, and evaluate efficacy safety II) Japanese MPM patients.
Lorlatinib is a novel third-generation tyrosine kinase inhibitor (TKI) which targets anaplastic lymphoma (ALK) as well receptor c-ros oncogene 1 (ROS1). A critical limitation of conventional ALK/ROS TKIs their association with acquired resistance mutations (particularly ALK G1202R and ROS1 G2032R) in the or gene, although these are not only mechanisms. Another this class drugs inadequate efficacy against central nervous system metastasis, likely attributable to blood-brain barrier (BBB)....
8101 Background: Somatic mutations in the epidermal growth factor receptor (EGFR) gene are associated with therapeutic response to EGFR tyrosine kinase inhibitors (EGFR-TKIs) patients (pts) advanced non-small cell lung cancer (NSCLC). Several phase II trials of EGFR-TKIs pts positive for such have yielded a high rate and good survival; however, number enrolled onto those was too small draw any firm conclusion. Methods: We carried out combined analysis seven prospective conducted Japan...
Many studies evaluated magnification endoscopy (ME) to correlate changes on the gastric mucosal surface with Helicobacter pylori (H. pylori) infection. However, few validated these concepts high-definition without ME.To access association between pattern under near focus technology and H. infection status in a western population.Cross-sectional study including all patients referred routine upper endoscopy. Endoscopic exams were performed using standard high definition (S-HD) followed by...
Reperfusion injury has been one of the serious problems in cardiac surgery and medicine. We report a novel method myocardial protection. Eight Sprague-Dawley rats, group A, were administrated green tea polyphenol orally. other B, received no medication. Isolated hearts perfused with Langendorff's apparatus, reperfused after 90min arrest. The left ventricular (LV) function, size, weight oxidative stress spaciotemporal analysis performed. LV size B became enlarged by 1.8+/-0.12 (mean+/-SD),...
3605
e14560 Background: UGT1A1*6 as well UGT1A1*28 polymorphisms is associated with decreased glucuronidation of SN-38, the active metabolite irinotecan (CPT-11). Although maximum tolerated dose (MTD) and recommended (RD) in Hetero was determined 150 mg/m 2 (approval Japan), those Homo were unknown. Methods: Pts received prior chemotherapies except for CPT-11 metastatic gastrointestinal cancer enrolled. UGT1A1 categorized into Wild(*1/*1), Hetero(*1/*28, *1/*6), Homo(*28/*28, *6/*6, *28/*6)....
407 Background: The KRAS mutation mainly located in the codon 12 and 13 indicates unresponsiveness of patients with metastatic colorectal cancer (CRC) to anti-epidermal growth factor receptor (EGFR) antibodies. Many studies have reported that approximately 30%-40% CRC mutations. However, clinicopathological features mutant not been fully clarified, especially Asian populations. This study aimed clarify comparison wild type large-scale Japanese population. Methods: key eligibility criteria...
Abstract Flange faces, in particular piping flange, often encounter mechanical and corrosion damages during the plant construction. Of damages, one is easier to identify terms of when it occurs what causes it, responsibilities for a repair or replacement clearly attributed which stakeholders, flange purchasers, manufacturers, stockiest, shipping companies, spool fabricators erectors. For damage, however, are argued among stakeholders because unknown why occurred. In order avoid this...