- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Retinal and Macular Surgery
- Ocular Diseases and Behçet’s Syndrome
- Intraocular Surgery and Lenses
- Vascular Malformations Diagnosis and Treatment
- Retinal Development and Disorders
- Dermatological and Skeletal Disorders
- Drug-Induced Ocular Toxicity
- Intracranial Aneurysms: Treatment and Complications
- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Renal and Vascular Pathologies
- Ocular Oncology and Treatments
- melanin and skin pigmentation
- Medical and Biological Sciences
- Vascular Tumors and Angiosarcomas
- Digital Innovation in Industries
- Management of metastatic bone disease
- Neurosurgical Procedures and Complications
- Health and Medical Studies
- Psoriasis: Treatment and Pathogenesis
- Ocular Disorders and Treatments
Vita-Salute San Raffaele University
2016-2024
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2017-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2017-2024
IRCCS Ospedale San Raffaele
2016-2021
San Raffaele University of Rome
2017
Bayer (Germany)
2016
Sanofi (France)
2016
Alcon (China)
2016
Bausch & Lomb (France)
2016
Roche (Switzerland)
2016
To analyze choriocapillaris (CC) vessel density (VD) around geographic atrophy (GA) secondary to non-neovascular dry age-related macular degeneration using optical coherence tomography angiography.We compared CC VD surrounding GA margin (500 μm radius) with control (outside margin) in a consecutive series of patients presenting between August 2016 and February 2017 at the Medical Retina Imaging Unit University Vita-Salute, IRCCS Ospedale San Raffaele Milan. Images were obtained through...
To compare the visual performance, spectacle independence, and subjective quality of 3 intraocular lenses (IOLs): monofocal, enhanced extended depth focus.Ophthalmology Department, San Raffaele Scientific Institute, Milan, Italy.Prospective case series.Patients without ocular comorbidities corneal astigmatism <0.75 diopters (D) undergoing cataract surgery with bilateral implantation monofocal Tecnis ZCB00, Eyhance ICB00, depth-of-focus Symfony ZXR00 IOLs were included. 6 months...
Aim To analyse quantitative optical coherence tomography angiography (OCTA) parameters of choriocapillaris (CC) at the foveal, perifoveal and parafoveal regions in healthy subjects different age. Methods In this observational cross-sectional study, consecutive underwent swept source OCTA (PLEX Elite 9000, Carl Zeiss Meditec, USA). 3×3 mm 6×6 scans centred on fovea were acquired analysed postprocessed with thresholding binarisation processes. The main outcome measures included CC features...
Aim To analyse the choriocapillaris (CC) flow status in area that subsequently showed geographic atrophy (GA) expansion secondary to age-related macular degeneration (AMD) during 1-year follow-up, matching optical coherence tomography angiography (OCT-A) and fundus autofluorescence (FAF). Methods In this prospective longitudinal observational study, 30 eyes of 20 consecutive patients with GA AMD (mean age 75.5±7.4 years) were included. All underwent OCT-A FAF at baseline follow-up. Main...
To investigate the application of optical coherence tomography angiography (OCT-A) in evaluation geographic atrophy (GA) secondary to age-related macular degeneration (AMD).Patients with GA were prospectively enrolled and studied blue fundus autofluorescence (FAF), en face structural OCT, OCT-A. OCT-A images acquired using a slab whole choroid, whereas OCT obtained at ellipsoid zone (EZ), choroidal (CH) level, scleral (SC) level. Three readers independently measured extension areas evaluated...
Aims To describe optical coherence tomography angiography (OCT-A) abnormalities of patients with pseudophakic cystoid macular oedema (PCMO) before and after pharmacological resolution, compared diabetic (DMO) normal eyes. Methods In this retrospective, observational study, 44 eyes (30 patients) were included: 15 (15 affected by PCMO; 14 healthy fellow used as negative control group; age-matched sex-matched DMO positive group. All underwent a complete ophthalmological examination at baseline,...
This review aims to give the reader an overview selectively oriented on safety and efficacy of surgery, providing concise direct answers about crucial questions trainees experts. Surgery for idiopathic epiretinal membrane (ERM) is a safe effective procedure that can achieve long-term stable postoperative visual anatomical improvement, with overall low recurrence complication rate. Young patients, short onset symptoms better initial acuity higher levels outcome. The preoperative degree...
Purpose To investigate optical coherence tomography angiography (OCT-A) findings in recurrent type 3 macular neovascularisation (MNV). Methods In this retrospective cohort study, consecutive patients with MNV secondary to age-related degeneration underwent OCT-A at three different time points: baseline, after anti-vascular endothelial growth factor treatment complete resolution of the exudative signs (ie, non-exudative stage) and recurrence exudation stage). Demographics clinical were...
Purposes To describe the prevalence of ocular features among COVID-19 patients and their relationship with clinical data, inflammatory markers respiratory support therapy (including CPAP); to investigate SARS-CoV-2 in secretions symptomatic patients.
To compare the anatomical and functional outcome of small (<250 µ m) medium (250-400 full-thickness macular holes (FTMHs) treated with internal limiting membrane (ILM) inverted flap (IF) or standard technique.Retrospective longitudinal analysis successfully operated eyes intermediate FTMH. Outcome measures were best-corrected visual acuity (BCVA), microperimetric sensitivity (with fixation stability), restoration external (ELM) ellipsoid zone (EZ) at 6 months.Fifty 50 FTMH included, half...
To analyze the optical coherence tomography angiography features of eyes affected with angioid streaks (AS) and to evaluate their ability predict choroidal neovascularization (CNV) activity.Angioid were individuated from a pool consecutive patients. Eyes without CNV evaluated by multimodal imaging.Thirty-eight 19 patients diagnosed AS included. Thirty 38 8 In majority cases, showed on tangled appearance always associated signs neovascular inactivity imaging (100%-0%, inactive-active,...
Purpose: To study multimodal imaging features of combined hamartoma the retina and retinal pigment epithelium (CHRRPE). Methods: Six patients (3 males, mean age 11 years) a healthy age-matched control group made up 15 subjects (8 12.6 were included in analysis. Complete ophthalmologic examination was performed, including best-corrected visual acuity, anterior posterior segment slit-lamp evaluation, tonometry. The protocol fundus images, structural optical coherence tomography (OCT),...
Purpose: To report the clinical features and outcomes of corneal toxicity following mirvetuximab soravtansine therapy. Methods: Five patients who were treated with evaluated in our hospital for ocular symptoms during a period 5 months between December 2017 April 2018. A complete ophthalmologic examination, including anterior segment infrared reflectance (AS-IR) optical coherence tomography (AS-OCT), was performed. Results: All female (average age, 62.4 ± 5.5 years) being advanced epithelial...
To compare choroidal neovascularization (CNV) area and vessel density (VD) measurements between two different swept-source optical coherence tomography angiography (SS-OCTA) devices.En face (OCTA) images of patients affected by neovascular age-related macular degeneration were collected prospectively from devices: Zeiss PLEX Elite 9000 (Carl Meditec, Dublin, CA) Topcon DRI OCT Triton SS-OCTA (Topcon, Tokyo, Japan). Choroidal VD measured analyzed with ImageJ software readers to evaluate the...
Abstract Purpose To assess the rate of occurrence and risk factors postsurgical macular edema (PSME) in eyes with idiopathic epiretinal membrane (iERM) or full-thickness hole (FTMH). Methods Retrospective longitudinal analysis all subjects scheduled for vitrectomy without combined cataract surgery over a 6-month period. Electronic medical charts imaging data were analyzed preoperatively at 1, 3 6 months after surgery. Results From 101 patients diagnosed iERM FTMH, 71 eligible study....