A5065650208- Vitamin D Research Studies
- Cardiac Imaging and Diagnostics
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Heart Rate Variability and Autonomic Control
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Hormonal Regulation and Hypertension
- Cardiovascular Disease and Adiposity
- Pituitary Gland Disorders and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Heart Failure Treatment and Management
- Atherosclerosis and Cardiovascular Diseases
- Coronary Artery Anomalies
- Vascular anomalies and interventions
- Lipoproteins and Cardiovascular Health
- Cardiac tumors and thrombi
- Non-Invasive Vital Sign Monitoring
- Cardiovascular Health and Disease Prevention
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
Institute of Cardiology
1985-2020
Medical University of Warsaw
2011-2018
Provincial Polyclinical Hospital in Toruń
2017-2018
Physiotherapy New Zealand
2015
Mossakowski Medical Research Institute, Polish Academy of Sciences
2013
Universitäts-Herzzentrum Freiburg-Bad Krozingen
2012
University of Alberta
2012
Polish Academy of Sciences
1989-2011
Wojewódzki Szpital Zespolony im. Jędrzeja Śniadeckiego
2002
Centralny Szpital Kliniczny
1997
Atherosclerosis, the underlying cause of coronary artery disease (CAD), has a significant inflammatory component. White blood cell count is an affordable and accessible way to assess systemic immune response, as it comprises many subgroups with distinct complex functions. Considering their multidirectional effect on atherosclerosis, new biomarkers integrating various leukocyte subgroups, Systemic Inflammatory Index (SII) Response (SIRI), were recently devised describe balance between...
Background: Heart rate variability (HRV) analysis is a clinical tool frequently used to characterize cardiac autonomic status. The aim of this study was establish normative values for short-term HRV parameters by considering their main determinants in school-aged children. Methods: Five-minute electrocardiograms were taken from 312 non-athlete children (153 boys) at age 6 13 years computation conventional time- and frequency-domain parameters. (HR), respiratory rate, age, body mass index,...
The incidence of ischemic heart disease (IHD) increases every year. This cardiovascular has an inflammatory factor in its etiology due to different immune cells that influence atherogenesis. New biomarkers-the Systemic Inflammatory Index (SII) and the Response (SIRI)-attempt describe pro- anti-inflammatory balance quantify complex impact system on atherosclerosis, while vitamin D a multidirectional human body, including systems. Hence, objective this research was analyze association between...
Heart rate variability (HRV) is primarily heart (HR) dependent, and therefore, different HR may exert impact on HRV. The objectives of the study were to evaluate effect HRV in children determine whether indices normalized are sex- age-related.Short-term ECG recordings performed 346 healthy children. Standard time frequency domain parameters analyzed four age subgroups (6-7, 8-9, 10-11, 12-13 years old). To investigate HRV, standard prevailing HR.Standard measures did not differ between...
Introduction: A deficiency of 25-hydroxyvitamin D (25(OH)D) (the standard biomarker for vitamin status) can have multiple impacts on the cardiovascular system.The aim study was to assess influence 25(OH)D severity coronary atherosclerosis and lipid profile.Material methods: The involved prospectively 637 patients subject catheterization.The stage assessed using Coronary Artery Surgery Study score (CASSS).Plasma concentration measured an electrochemiluminescent immunoassay.The levels total...
Ischaemic heart disease is the main cause of death in developed countries. There are many modifiable risk factors associated with coronary (CAD). A growing number studies point to vitamin D deficiency as a factor for attacks and conditions cardiovascular disease. This study aimed analyse relationship between level 25-hydroxyvitamin (25(OH)D) severity artery atherosclerosis 25(OH)D levels non-diabetic patients hospitalised due acute syndrome those diagnosed stable CAD.oronary angiography was...
Elinogrel is the only selective, competitive and reversible platelet P2Y(12) inhibitor available in both intravenous (IV) oral formulations.This substudy of Intravenous Oral Administration to Evaluate Tolerability Efficacy Nonurgent Percutaneous Coronary Intervention patients (INNOVATE-PCI) trial evaluated pharmacokinetic pharmacodynamic effects two dosing regimens IV followed by elinogrel (120 mg plus 100 twice daily; 120 150 daily) versus standard clopidogrel therapy (300-600 loading dose...
Hand grip strength (HGS) test is commonly used as an indicator of overall muscle in medical and sport practices. Recently, several studies have proposed that the measurement maximal HGS depends on dynamometer's handle position. The aim present study was to identify optimal position obtain using hand dynamometer (HGD) for school-aged children.HGS assessed with Jamar digital HGD. Each participant performed three maximum contractions each positions progressing from first third position.A total...
Coronary artery disease (CAD), the leading cause of death worldwide, has an underlying in atherosclerosis. The activity this inflammatory process can be measured with neutrophil-to-lymphocyte ratio (NLR). anti-inflammatory and anti-atherogenic properties vitamin D affect many mechanisms involved CAD. In study, we investigated association between NLR, concentration, severity CAD a group patients history myocardial infarction (MI). NLR was higher acute coronary syndrome (ACS) comparison to...
Several modifiable factors may influence cardiac function in diabetic patients. The aim of the study was to evaluate vitamin D level on stage coronary atherosclerosis patients diagnosed with type 2 diabetes. performed 337 consecutive undergoing coronarography. evaluated using Coronary Artery Surgery Study Score. plasma 25(OH)D concentration determined by an electrochemiluminescence method. Patients without significant lesions arteries presented highest level, significantly higher than one-,...
To determine whether the echocardiographic presentation allows for diagnosis of acromegalic cardiomyopathy. 140 patients with acromegaly underwent echocardiography as part routine diagnostics. The results were compared control group comprising 52 age- and sex-matched healthy volunteers. Patients presented higher BMI, prevalence arterial hypertension, glucose metabolism disorders (i.e., diabetes and/or prediabetes). In acromegaly, following findings detected: increased left atrial volume...
Despite the preserved LVEF, patients with acromegaly are characterized by subclinical systolic dysfunction i.e., abnormal global longitudinal strain (GLS) assessed speckle tracking echocardiography (STE). The effect of treatment on LV function STE, has not been evaluated so far.Thirty-two naïve acromegalic without detectable heart disease were enrolled in a prospective, single-center study. 2D-Echocardiography and STE performed at diagnosis, 3&6 months preoperative somatostatin receptor...
The prevalence of coronary artery disease (CAD) increases every year; however, the impact microelements on its underlying cause—atherosclerosis—is still unclear. Copper plays numerous regulatory roles in cardiovascular health and was suggested to influence classic risk factors for CAD. copper-to-zinc-ratio (Cu/Zn-ratio) reflects systemic oxidative stress–one complex pathogenesis atherosclerosis. Hair incorporates metal ions during growth; thus, it exposure that occurred over last 4–8 weeks....
Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Although zinc (Zn) was reported to have antioxidant, anti-inflammatory and protective properties in CVDs, its association with coronary artery disease (CAD) is still unclear. As methods commonly used assess Zn levels blood urine do not show full picture microelement supply, this study, nutritional status patients angiographically confirmed CAD assessed using inductively coupled plasma optical emission spectrometry. We...
Coronary arteries have been extensively described and recognized by gross anatomic studies. However, in the clinical setting, recognition of conal artery is essential during coronary angiography, as well certain congenital heart conditions such tetralogy Fallot. In order to provide a complete physiologic correlation actual incidence distribution we examined 300 formalin fixed hearts with dissections angiograms. The was identified all five main patterns were recognized. Type A (193, 32.1%),...
Assessment of prognostic significance NT-proBNP level and the effects invasive (I) conservative (C) treatment acute myocardial infarction (AMI) in patients over 65.One-year survival was assessed 286 consecutive with AMI aged 65-100 (79 ± 8) subjected to I or C (136 150 individuals), respectively.245 (85%) survived in-hospital stay: 124 (91.1%) received 121 (80.6%) treatment. Heart failure (HF) diagnosed 30 receiving (22.6%) 71 (47.3%), p < 0,0001. levels latter group were significantly...
Introduction: The aim of the study was to evaluate global longitudinal strain (GLS) in patients with naive acromegaly normal left ventricular (LV) ejection fraction (EF). Material and methods: Forty-three consecutive LV systolic function as measured by EF, examined from 2008 2016, 52 a control group matched for age sex underwent two-dimensional speckle-tracking echocardiography assess GLS. Results: median GLS significantly lower than (in %, –16.6 vs. –20.7; p < 0.01). majority acromegalic (n...
Background: The ratio of mitral end‐diastolic velocity and annular early diastolic motion (E/e’) has predictive value in patients with acute coronary syndromes (ACS). Both E e’ velocities change age. prognostic E/e’ elderly ACS not been established yet. aim the study was to assess significance over 65 ACS. Method: involved 168 patients, mean age 79 years. Echocardiography performed within first 24 hours Clinical evaluation, 6‐minute walk test, echocardiography plasma level NT pro‐BNP were 12...
Background: Postmenopausal women experience rapid progression of coronary artery disease. Vitamin D deficiency appears to be a modifiable risk factor for cardiovascular diseases. This study aimed analyze the impact 25-hydroxyvitamin D3 (25(OH)D) level on severity atherosclerosis and its potential cardioprotective effect in postmenopausal women. Material Methods: The prospectively recruited 351 age undergoing angiography. was assessed using Coronary Artery Surgery Study Score (CASSS). A...
Coronary artery disease continues to be the leading cause of death in developed countries. Elevated mean platelet volume (MPV) is associated with an increased incidence myocardial infarction (MI) and MI-related mortality. Vitamin D concentrations affect level function platelets, which are crucial mediator atherothrombosis plaque rupture. The main aim this study was examine relationship serum 25-hydroxyvitamin (25(OH)D) levels activity patients a history acute coronary syndrome (ACS). This...
Benign myxomas are the most common primary tumors in left atrium of heart, and they usually require urgent operative management. However, with constant aging population treatment patients severe concomitant diseases, an interesting question is efficacy conservative approach. We present a case 75-year-old woman who was previously diagnosed atrial myxoma, underwent operation to resect it then developed recurrent tumor at site resection, which found by control echocardiography 1.5 years later....