A5031159327- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pulmonary Hypertension Research and Treatments
- Pericarditis and Cardiac Tamponade
- Medical Imaging and Pathology Studies
- Mycobacterium research and diagnosis
- Myasthenia Gravis and Thymoma
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Tuberculosis Research and Epidemiology
- Venous Thromboembolism Diagnosis and Management
- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Inhalation and Respiratory Drug Delivery
- Infectious Diseases and Mycology
- Lung Cancer Treatments and Mutations
- Occupational exposure and asthma
- Sarcoidosis and Beryllium Toxicity Research
- Cardiac tumors and thrombi
- Pneumothorax, Barotrauma, Emphysema
- Radiomics and Machine Learning in Medical Imaging
- Infective Endocarditis Diagnosis and Management
- Infectious Diseases and Tuberculosis
- Vascular Anomalies and Treatments
- Neuroendocrine Tumor Research Advances
- Atomic and Subatomic Physics Research
- Systemic Sclerosis and Related Diseases
National Institute of Public Health
2006-2025
Instytut Gruźlicy i Chorób Płuc
2010-2021
National Institute of Research in Tuberculosis
2021
Masih Daneshvari Hospital
2004-2016
National Center for Tuberculosis and Lung Disease
2010-2014
European Respiratory Society
2011
Wojskowy Instytut Medyczny
2010
4. Wojskowy Szpital Kliniczny z Polikliniką
2008
Idiopathic pulmonary fibrosis (IPF) is a rare disorder concerning elderly people, predominantly men, active or former smokers, with progressive nature and leading to premature mortality. The cause of the disease unknown. However, there are some risk factors, among which genetic predisposition plays role. aim our single-centered observational study was assess correlation between single nucleotide polymorphism (SNP) MUC5B gene (rs35705950) course, antifibrotic treatment effect, survival in...
Sarcoidosis is a multiorgan, granulomatous disease of an unknown etiology. The characteristic feature the formation noncaseating granulomas. Spontaneous resolution occurs in most patients, but clinical course may be chronic or progressive, complicated by pulmonary fibrosis, which major cause mortality sarcoidosis. Recent studies have provided new information on immunological mechanisms fibrosis. Its pathogenesis includes alteration lymphocyte activity and imbalance between their...
A Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing disease 2019 (COVID-19) led to a pandemic outbreak in 2019. COVID-19's course and its treatment immunocompromised patients are uncertain. Furthermore, there is possibility of protracted SARS-CoV-2 infection the need for repeated antiviral treatment. Monoclonal antibodies against CD20, which used, among other things, therapy chronic lymphocytic leukaemia follicular lymphoma, can induct immunosuppression. We present case...
Chronic thromboembolic pulmonary hypertension (CTEPH) is an ominous disease leading to progressive right heart failure. Selected patients can be treated by endarterectomy (PEA). We assessed long-term clinical outcome of with CTEPH who underwent PEA and remained on medical treatment alone. A total 112 consecutive referred between 1998 2008 one center were followed for a mean 35 (range 0-128) months after diagnosis. All the had advanced at baseline. The operated group higher World Health...
Fibrotic hypersensitivity pneumonitis (fHP) shares many features with other fibrotic interstitial lung diseases (ILD), and as a result it can be misdiagnosed idiopathic pulmonary fibrosis (IPF). We aimed to determine the value of bronchoalveolar lavage (BAL) total cell count (TCC) lymphocytosis in distinguishing fHP IPF evaluate best cut-off points discriminating these two ILD.A retrospective cohort study patients diagnosed between 2005 2018 was conducted. Logistic regression used diagnostic...
The aim of the study was to assess prognostic value cytokeratin 19 fragments (Cyfra 21-1), carcinoembryonic antigen (CEA) and C-reactive protein (CRP) in surgically treated NSCLC patients.50 patients (25 adenocarcinoma, 21 squamous cell 4 adenosquamous), clinical stages I II, age 42-89 years, entered study. CEA, Cyfra 21-1 CRP concentrations were measured serum taken before surgery, CEA 50 patients, - 46 patients. survival calculated from date surgical treatment until death or end...
Pulmonary hypertension (PH) is a well-recognised complication of interstitial lung diseases (ILD), which worsens prognosis and impairs exercise capacity. Echocardiography the most widely used, non-invasive method for PH assessment. The aim our study was to identify factors predictive echocardiographic signs in newly recognised ILD patients.
Hypersensitivity pneumonitis (HP) is an exposure-related interstitial lung disease with two phenotypes-fibrotic and non-fibrotic. Genetic predisposition important factor in the pathogenesis fibrosis development. Several genes are supposed to be associated fibrosing cascade lungs. One of best-recognized most prevalent common MUC5B gene promoter region polymorphism variant rs35705950. The aim our study was establish frequency minor allele population patients HP find relationship between...
Interferon gamma releasing assays (IGRAs) are extensively used in the diagnosis of latent tuberculosis infections. Comparing to tuberculin skin test (TST) they lack false positive results populations vaccinated with BCG, and most non-tuberculous mycobacteria (NTM) Nevertheless, Mycobacterium kansasii, marinum, szulgai may induce IGRAs due RD1 homology tuberculosis. The aim study was investigate possible influence NTM respiratory isolates on IGRAs. 39 patients (23 females 16 males) median age...
A positive cytology result in pericardial fluid is the gold standard for recognition of malignant effusion. Unfortunately, 30-50% patients with effusion cytological examination negative. Tumor marker assessment may help to recognize The aim our study was estimate value CYFRA 21-1 and CEA measurement To knowledge this first on examined group consisted 50 34 non-malignant Median concentrations were 80 ng/mL (0-317) 0.5 (0-18.4), respectively (p<0.001). 260 (5.3-10080) 22.4 (1.87-317.6),...
Introduction: Hypersensitivity pneumonitis (HP) is the third most common interstitial lung disease after idiopathic pulmonary fibrosis and nonspecific pneumonia. Pathogenesis of HP related to repeated exposure inhaled environmental antigens that sensitise susceptible, genetically predisposed persons. The aim present retrospective study was summarise diagnostic methods used in consecutive patients with HP, recognised a single unit, between 2005 2015, compare them current criteria. Material...