A5101423183- Peptidase Inhibition and Analysis
- Influenza Virus Research Studies
- Cutaneous lymphoproliferative disorders research
- Lymphoma Diagnosis and Treatment
- Neuropeptides and Animal Physiology
- Cancer and Skin Lesions
- HIV/AIDS drug development and treatment
- Cutaneous Melanoma Detection and Management
- Animal Virus Infections Studies
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Inflammatory Myopathies and Dermatomyositis
- Monoclonal and Polyclonal Antibodies Research
- Histiocytic Disorders and Treatments
- Viral Infections and Immunology Research
- Nonmelanoma Skin Cancer Studies
- Protease and Inhibitor Mechanisms
- Nail Diseases and Treatments
- Metabolism and Genetic Disorders
- Vascular Tumors and Angiosarcomas
- Cancer Diagnosis and Treatment
- Genetic and rare skin diseases.
- Multiple and Secondary Primary Cancers
- Drug Transport and Resistance Mechanisms
- Viral-associated cancers and disorders
The Ohio State University
2025
University of Liège
2020-2024
Centre Hospitalier Universitaire de Liège
2013-2023
Munster Technological University
2008-2015
The Francis Crick Institute
2014
Dublin City University
2001-2004
John Jay College of Criminal Justice
1980
City University of New York
1980
New York State Psychiatric Institute
1978
Columbia University Irving Medical Center
1972
Group C rotaviruses are important human enteric pathogens that have also been detected in a variety of mammalian species, including pigs. identified piglets with diarrhea, but their ecology remains to be elucidated. By screening 292 fecal samples collected from 4- 5-week-old asymptomatic pigs four herds Ireland between 2005 and 2007, 13 (4.4%) tested positive by reverse transcription-PCR for group rotavirus. A were 19 not conjunction viruses. The gene encoding the major neutralization...
Livestock animals have been the assumed source of several human epidemics in recent years, for example, influenza H1N1, rotavirus G8/G9, and MERS-CoV. Surveillance novel viruses is essential to evaluate risk animal health determine any economic impact, failure thrive. There a paucity data regarding detection characterisation gastroenteritis viruses, particularly porcines Ireland. Recently, number small porcine DNA emerged globally, torque teno sus virus, bocavirus, parvoviruses 2 & 4, little...
findings may, as in the present case, indicate a combination of traits indicative psoriasis and toxicoderma [7, 8].In most these patients, lesions can be controlled with topical therapy [4][5][6] however, skin condition not only worsened when anticancer was stopped (perhaps because cessation coincided withdrawal oral corticosteroids) but also prevented use alternative therapies to halt tumour progression.Ixekizumab is an anti-IL-17A drug approved for treatment moderate-to-severe plaque...
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic pathology in Western countries. It encompasses a spectrum of conditions ranging from simple steatosis to more severe and progressive non-alcoholic steatohepatitis (NASH) that can lead hepatocellular carcinoma (HCC). Obesity related metabolic syndrome are important risk factors for development NAFLD, NASH HCC. DUSP3 small dual-specificity protein phosphatase with poorly known physiological function. We investigated...
It remains unclear whether multiple primary melanoma (MPM) patients have a worse survival prognosis compared with single (SPM) patients. To investigate the demographics, histological features, and of MPM versus SPM Cox regression analyses between Furthermore, demographics features cohort were retrieved from dermatopathology files 2000 2019. Out 3853 patients, 95 retrieved: 81 two melanomas (85.2%) 14.8% three or more. Mean Breslow first was 0.84 mm [minimum (min): 0 mm, maximum (max): 16...
<b><i>Background:</i></b> The advancing evolution toward a Th2 immune environment confers progressive immunosuppression in patients with longstanding cutaneous T-cell lymphoma (CTCL). conjunction of the disease-related as well immunosuppressive character some CTCL treatments increase risk infectious and neoplastic diseases, sometimes fatal outcomes. <b><i>Objectives:</i></b> aim study was to prospectively causes death cohort patients, tertiary...
Risankizumab, an interleukin (IL)-23 antagonist, is a highly effective treatment for moderate to severe psoriasis. Crusted scabies (CS) rare and form of scabies, occurring mainly in immunosuppressed patients and/or neurologically or mentally ill patients. A young girl with Down syndrome was diagnosed hyperkeratotic As topical dermocorticosteroids, UVB-phototherapy acitretin 6 weeks did not improve the lesions, two injections risankizumab were administered. Following these injections, lesions...
Cutaneous metastases of breast cancer remain a therapeutic challenge. Oxygen flow-assisted topical administration methotrexate 5% (OFAMTX, in carrier solution) has recently been proven to be an efficacious alternative treatment for extramammary Paget's disease, which is considered situ mammary adenocarcinoma the epidermis. A 51-year-old patient with triple negative presenting biopsy-proven skin on chest agreed OFAMTX5%. The duration was 2 weeks and consisted twice-weekly sessions OFAMTX5%...
Necrobiosis lipoidica (NL) is a rare granulomatous skin disorder of unknown physiopathology that frequently associated with diabetes mellitus. The typical lesions NL present as chronic, bilateral, well-defined red to yellow-brown plaques telangectasias, violaceous border and waxy atrophic center. lower legs are the most often involved areas, but may exceptionally develop on scar tissue following surgery. treatment very challenging notoriously difficult. We report 60-year-old diabetic woman...
Introduction: Eustachian tube dysfunction is a common side effect of radiotherapy for head and neck cancers or brain tumors, although few effective treatments exist. The Kent-Collins Protocol represents novel therapeutic option post-radiotherapy dysfunction. Case Description: was employed in one patient with following fractionated stereotactic cerebral metastases from HER-2 positive breast cancer. provided relief symptoms (conductive hearing loss, aural fullness, otalgia) range 5 to 45...
Aleukemic leukemia cutis (ALC) is a rare condition and concerns less than 10% of (LC) cases. LC defined as cutaneous infiltration neoplastic myeloid or lymphoid blasts, which occurs in the absence any prior bone marrow peripheral blood involvement. A pediatric case B-cell ALL presenting ALC presented because an exceptional testicular localization. acute lymphoblastic rarely described literature, this could be first childhood with
Introduction The histological pattern of pseudo-epitheliomatous hyperplasia (PEH) may be encountered in a large series verruciform/crateriform skin lesions (VC) with or without central ulceration/crusting. Beside neoplastic and inflammatory processes, this clinico-histological associated an extensive range infectious agents. Materials Methods A literature search was performed to identify viral, bacterial, fungal, parasitic mucocutaneous infections potentially presenting clinical/histological...
There are enzymes that specifically recognise the amino acid proline within peptides and proteins called post-proline cleaving enzymes. Many of them implicated in neurodegenerative disorders psychiatric diseases. ZIP is one such newly-discovered peptidase. In this work, it has been purified from bovine serum subjected to various analytical studies order characterise it. A series reactions between synthesised were carried out elucidate size specificity active site enzyme. On-line LC-MS was on...