G. Grimble

ORCID: 0000-0003-1719-0683
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About
Contact & Profiles
Research Areas
  • Clinical Nutrition and Gastroenterology
  • Nutrition and Health in Aging
  • Diet and metabolism studies
  • Cerebral Palsy and Movement Disorders
  • Child Nutrition and Feeding Issues
  • Metabolism and Genetic Disorders
  • Digestive system and related health
  • Spinal Cord Injury Research
  • Infant Nutrition and Health
  • Child Nutrition and Water Access
  • Nutritional Studies and Diet
  • Gastrointestinal motility and disorders
  • Obesity, Physical Activity, Diet
  • Muscle metabolism and nutrition
  • Food Security and Health in Diverse Populations
  • Folate and B Vitamins Research
  • Hip and Femur Fractures
  • RNA modifications and cancer
  • Helicobacter pylori-related gastroenterology studies
  • Nutrition, Genetics, and Disease
  • Childhood Cancer Survivors' Quality of Life
  • Electrolyte and hormonal disorders
  • Iron Metabolism and Disorders
  • Amino Acid Enzymes and Metabolism
  • Fibromyalgia and Chronic Fatigue Syndrome Research

University College London
2011-2023

Faculty (United Kingdom)
2016

University College Lahore
2015

University College Hospital
2010-2012

UCL Australia
2010

University of Reading
2007-2009

University of Surrey
2000-2007

University of Roehampton
1995-2004

King's College London
2001-2003

King's College Hospital
2003

Certain probiotics may prevent the development of antibiotic-associated diarrhoea (AAD) and Clostridium difficile-associated (CDAD), but their effectiveness depends on both strain dose. There are few data nutritional interventions to control AAD/CDAD in spinal cord injury (SCI) population. The present study aimed assess (1) efficacy consuming a commercially produced probiotic containing at least 6·5 × 10⁹ live Lactobacillus casei Shirota (LcS) reducing incidence AAD/CDAD, (2) whether...

10.1017/s0007114513002973 article EN British Journal Of Nutrition 2013-09-18

Sixty nine patients with non-ulcer dyspepsia have been studied endoscopy, biopsy, quick urease (CLO) test, Helicobacter pylori culture, and the 13C-urea breath test before after treatment tripotassium dicitratobismuthane (DeNol) two tablets twice daily for four weeks. Symptoms of were recorded using a standard questionnaire. Using H culture as gold standard, sensitivity was 90%, specificity 98.6%, accuracy 94.8% positive predictive value 98.2% negative 92.5%. Conversion rate from to status...

10.1136/gut.31.11.1237 article EN Gut 1990-11-01

An automated method of chemiluminescence analysis nitrogen used routinely for 4 yr. Liquid samples (urine, enteral, and parenteral feeds) required simple dilution, whereas feces a modified acid-digestion procedure, before analysis. For urine samples, the coefficient variation was within batch from 0.9-3.6%, between 4.3-7.6%. At sample injection rate 2 microliter/sec, useful dynamic range, diluted 1:200, 0-14 g N/liter. Precision fecal 3.8-6.7% low to high content. The correlation this...

10.1177/0148607188012001100 article EN Journal of Parenteral and Enteral Nutrition 1988-01-01

1. In the first part of study, absorption lactitol, a new disaccharide analogue lactose, was studied using an in vivo jejunal perfusion technique man. Intestinal uptake lactitol from isotonic solutions containing 10, 30, 60, and 100 mmol lactitol/l insignificant. 2. second study laxative threshold determined compared with that sorbitol double-blind, randomized, cross-over on twenty-one normal subjects. Laxative considered to be either maximum dose tolerated without unacceptable diarrhoea or...

10.1079/bjn19870025 article EN British Journal Of Nutrition 1987-03-01

Ten patients with histologically proven cirrhosis, admitted in grade I to II acute hepatic coma, received addition a standard dietary protein free "anticoma" regime, continuous nasogastric infusion of branched-chain amino acid enriched chemically defined enteral diet (Hepaticaid) containing an equivalent 70 g protein/day for mean 7.3 days (range 3-23). No complications therapy were observed and, specifically, the use fine bore tubes did not provoke variceal hemorrhage. Overall positive...

10.1177/0148607183007004346 article EN Journal of Parenteral and Enteral Nutrition 1983-07-01

Data on the prevalence of malnutrition among patients with spinal cord injuries (SCI) are lacking. The aim present study was to assess nutritional risk at admission, and status support in UK SCI Centres (SCIC); a cross-sectional, multicentre four SCIC. A standardised questionnaire used distributed participating After obtaining informed consent, baseline demographic data, score by ‘Malnutrition Universal Screening Tool’, BMI routine blood biochemistry were collected from every patient...

10.1017/s0007114511006234 article EN British Journal Of Nutrition 2011-12-15

Cunniffe, B, Papageorgiou, M, O'Brien, Davies, NA, Grimble, GK, and Cardinale, M. Acute citrulline-malate supplementation high-intensity cycling performance. J Strength Cond Res 30(9): 2638-2647, 2016-Dietary L-citrulline-malate (CM) consumption has been suggested to improve skeletal muscle metabolism contractile efficiency, which would be expected predispose exercising individuals greater fatigue resistance. The purpose of this study was examine the effects CM on acid-base balance exercise...

10.1519/jsc.0000000000001338 article EN The Journal of Strength and Conditioning Research 2016-01-24

Rising use of foodbanks highlights food insecurity in the UK. Adverse life events (e.g. unemployment, benefit delays or sanctions) and financial strains are thought to be drivers foodbank use. This research aimed explore who uses foodbanks, factors associated with increased insecurity. We surveyed those seeking help from front line crisis providers (N = 270) a comparison group Advice Centres (ACs) 245) relation demographics, adverse events, strain household security. About 55.9% users were...

10.1093/pubmed/fdx133 article EN Journal of Public Health 2017-09-13

Objective To determine whether critically ill children are hypermetabolic and to calculate predictive equations appropriate for children. Design Prospective, clinical study. Setting Pediatric intensive care unit. Patients A total of 57 (39 boys) aged 9 months 15.8 yrs. Interventions None. Measurements Main Results The median resting energy expenditure measurement measured by indirect calorimetry was 37.2 (range, 11.9–66.6) kcal·kg−1·day−1. This significantly lower than would be predicted...

10.1097/01.pcc.0000059425.09149.d8 article EN Pediatric Critical Care Medicine 2003-04-01

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10.1079/nrr19890009 article EN Nutrition Research Reviews 1989-01-01
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