A5008324390- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Organ Transplantation Techniques and Outcomes
- Surgical Simulation and Training
- Renal Transplantation Outcomes and Treatments
- Liver Disease Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Intraperitoneal and Appendiceal Malignancies
- Gastrointestinal Tumor Research and Treatment
- Anatomy and Medical Technology
- Liver physiology and pathology
- Metastasis and carcinoma case studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Cancer Cells and Metastasis
- Bariatric Surgery and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Diversity and Career in Medicine
- Urinary Tract Infections Management
- Advanced Radiotherapy Techniques
- Innovations in Medical Education
- Transplantation: Methods and Outcomes
- Enhanced Recovery After Surgery
- Heme Oxygenase-1 and Carbon Monoxide
University Hospital Münster
2008-2025
Klinik und Poliklinik für Psychosomatik und Psychotherapie
2012-2024
University Medical Centre Mannheim
2024
Heidelberg University
2024
University Hospital Heidelberg
2024
University Medical Center Utrecht
2023
University of Münster
2001-2010
Objective: This international multicenter study by the Upper GI International Robotic Association aimed to gain insight in current techniques and outcomes of RAMIE worldwide. Background: Current evidence for originates from single-center studies, which may not be generalizable experience. Methods: Twenty centers Europe, Asia, North-America, South-America participated 2016 2019. Main endpoints included surgical techniques, clinical outcomes, early oncological results ramie. Results: A total...
Non-alcoholic fatty liver disease (NAFLD) is a common problem with wide variety of phenotypes. While its pathogenesis still not fully understood, several risk factors for progression have been identified. Therefore, defining adequate animal models may serve to unreveal the in NAFLD. We studied Lewis and Sprague-Dawley rats both genders ( n = 6) fed standard (Std) or high-fat (HF) diet three weeks. Disease stage was assessed by haematoxylin–eosin, Azan Heidenheim Oil-Red staining, apoptosis...
Abstract Background Surgical training persists of intensive work, incessant practice, and, most importantly, experience. Owing to the changing surgical environment, increasing specialization, and rapid development minimally invasive techniques, new innovative approaches in are necessary achieve excellent postgraduate education. Here, we introduce a skills lab that offers multi-course program featuring concise, modular curriculum comprising well-defined simple-to-follow procedures,...
The shortage of organ donors has led to the introduction Eurotransplant Senior Program (ESP) optimize allocation kidneys from elderly by age-matching. In face a rapidly aging population, identification prognostic factors for kidney allograft survival within ESP population will be enormous significance.Donor and recipient data 89 patients transplanted under protocol between 1999 2007 were retrospectively analyzed. Data correlated with initial graft function, survival, acute rejection...
Abstract Background Robot-assisted minimally invasive esophagectomy (RAMIE) is increasingly adopted in centers worldwide, with ongoing refinements to enhance results. This study aims assess the current state of RAMIE worldwide and identify potential areas for improvement. Methods descriptive analyzed prospective data from esophageal cancer patients who underwent transthoracic Upper GI International Robotic Association (UGIRA) centers. Main endpoints included textbook outcome rate, surgical...
Abstract Background Currently, little is known regarding the optimal technique for abdominal phase of RAMIE. The aim this study was to investigate outcome robot-assisted minimally invasive esophagectomy (RAMIE) in both and thoracic (full RAMIE) compared laparoscopy during (hybrid laparoscopic RAMIE). Methods This retrospective propensity-score matched analysis International Upper Gastrointestinal Robotic Association (UGIRA) database included 807 RAMIE procedures with intrathoracic...
The coronavirus disease (COVID-19) has significantly changed healthcare systems and medical education. Universities were required to develop innovative curricula based on remote distance education continue This prospective questionnaire-based study aimed investigate the impact of COVID-19-associated learning surgical training students.A 16-item survey was distributed students at University Hospital Münster before after a skills laboratory (SSL). Two cohorts included: summer semester 2021...
The increasing demand for transplantation has led to consideration of liver grafts from donors exposed hepatitis B virus (HBV). Six transplantations surface antigen (HBsAg) positive have been reported; two recipients suffered HBV/HDV (hepatitis Delta virus) coinfection and were followed up 10-12 months. Here, we report a 56 months follow-up HBV/HDV-coinfected recipient HBsAg graft. Posttransplant combination prophylaxis consisted immunoglobulin, lamivudine adefovir dipivoxil. remained during...
Objective: To gain insight into the global practice of robot-assisted minimally invasive gastrectomy (RAMIG) and evaluate perioperative outcomes using an international registry. Background: The techniques RAMIG for gastric cancer vary substantially in literature. Methods: Prospectively registered cases (≥10 per center) were extracted from 25 centers Europe, Asia, South-America. Techniques resection, reconstruction, anastomosis, lymphadenectomy analyzed related to surgical oncological...
Abstract During the education of next generation scientists in experimental research, careful instruction surgical techniques is major importance. This applies particular to complicated microsurgical models, which require a structured teaching concept with clearly laid‐down working steps and adequate didactic resources. Transplantations rats are undoubtedly among most difficult models surgery. Because completely sutured orthotopic liver transplantation kidney have been practiced for many...
The regeneration capacity of cirrhotic livers might be affected by angiotensin-1 (AT1) receptors located on hepatic stellate cells (HSC). effect AT1 receptor blockade microcirculation, fibrosis and liver was investigated.In 112 Lewis rats, cirrhosis induced repetitive intraperitoneal injections CCl(4) . Six hours, 3, 7 14 days after partial hepatectomy or sham operation, rats were sacrificed for analysis. Animals treated with either vehicle 5 mg/kg body weight losartan pre-operatively once...
Rejection of a liver transplant is rare but serious event which can be life threatening. T-cells were supposed to the major, if not only key player in allograft rejection. However, during recent years B-cell function has regained attention. A chimeric monoclonal antibody against CD20 protein (rituximab) successfully reversed multi-drug resistant rejection recipient. Following an uncomplicated postoperative course, patient showed biopsy-confirmed acute on day 28. Despite treatment with...
Abstract Background Microsurgical techniques are an important part of clinical and experimental research. Here we present our step-by-step microsurgery training course developed at the Münster University Hospital. The goal this was to create a short, modular curriculum with clearly described easy follow working steps in accordance Guidelines for Training Surgical Research Animals by Academy Research. Methods Over 10 years, conducted annual 2.5 day (20 h) microsurgical total 120 participants....
359 Background: Peritoneal relapse is seen in 60-70% of patients with diffuse type gastric cancer (gc), compared to 20-30% intestinal according Laurens`s classification. Hyperthermic intraperitoneal chemoperfusion (HIPEC) an increasingly used therapy method for (pts) peritoneal metastases. The preventive use HIPEC could represent approach cell gc pts before macroscopic seeding has evolved, since operable disease are fit and may have potential risk microscopic involvement, thus having a...