Felice Borghi
A5027951673- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Enhanced Recovery After Surgery
- COVID-19 and healthcare impacts
- Gastric Cancer Management and Outcomes
- Anorectal Disease Treatments and Outcomes
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Screening and Detection
- Appendicitis Diagnosis and Management
- Abdominal Surgery and Complications
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Hernia repair and management
- Surgical site infection prevention
- Metastasis and carcinoma case studies
- Trauma and Emergency Care Studies
- Esophageal Cancer Research and Treatment
- Pelvic floor disorders treatments
- Pancreatitis Pathology and Treatment
- Colorectal and Anal Carcinomas
- Genetic factors in colorectal cancer
- Gastrointestinal motility and disorders
- Nutrition and Health in Aging
- Cancer Genomics and Diagnostics
- Colorectal Cancer Treatments and Studies
Candiolo Cancer Institute
2021-2025
Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo
2008-2024
Jisc
2024
Carle Foundation Hospital
2021-2023
Ospedale Maggiore
2023
Ospedale “M. Bufalini” di Cesena
2022
Saitama Medical University
2022
Ospedali Riuniti Marche Nord
2021
Collaborative Group (United States)
2021
Merck (Germany)
2020
What is the quantitative risk of gastric cancer in first-degree
Anastomotic leakage after restorative surgery for rectal cancer shows high morbidity and related mortality. Identification of risk factors could change operative planning, with indications stoma construction. This retrospective multicentre study aims to assess the anastomotic leak rate, identify independent develop a clinical prediction model calculate probability leakage.The used data from 24 Italian referral centres Colorectal Cancer Network Society Surgical Oncology. Patients were...
Abstract Background The purpose of this study was to test use the Dutch leakage score (DLS), serum C-reactive protein (CRP) and procalcitonin (PCT) in diagnosis anastomotic (AL) after elective colorectal resection a prospective observational study. Methods Patients undergoing with anastomosis 19 centres were enrolled over 1-year period from September 2017. DLS CRP PCT levels evaluated on postoperative day (POD) 2, POD3 POD6. Statistical analysis, including determination area under receiver...
Objective: To assess overall (OS), time to progression (TTP), and disease-free survival (DFS) at 3 years after treatment, comparing stenting as bridge-to-surgery (SBTS) versus emergency surgery (ES) in neoplastic left colon obstruction, secondary endpoints of the previously published randomized controlled trial. Background: While SBTS obstruction may reduce morbidity need for a stoma compared with ES, concern has been raised, about long-term survival. Methods: Individuals affected by...
Abstract Background The spread of the SARS-CoV2 virus, which causes COVID-19 disease, profoundly impacted surgical community. Recommendations have been published to manage patients needing surgery during pandemic. This survey, under aegis Italian Society Endoscopic Surgery, aims analyze how surgeons changed their practice Methods authors designed an online survey that was circulated for completion departments general registered in Ministry Health database December 2020. Questions were...
Abstract Background In Italy, surgeons continue to drain the abdominal cavity in more than 50 per cent of patients after colorectal resection. The aim this study was evaluate impact placement on early adverse events undergoing elective surgery. Methods A database retrospectively analysed through a 1:1 propensity score-matching model including 21 covariates. primary endpoint postoperative duration stay, and secondary endpoints were surgical site infections, infectious morbidity rate defined...
Background Enhanced recovery after surgery (ERAS) protocols are known to potentially improve the management and outcomes of patients undergoing colorectal surgery, with limited evidence their implementation in hospital networks a large population. We aimed assess impact an ERAS protocol cancer entire region Piemonte, Italy, supported by audit feedback (A&F) intervention. Methods A large, stepped wedge, cluster randomised trial enrolled scheduled for elective at 29 general units...
Obtaining a valid informed consent in the medical and surgical field is long debated issue literature. In robotic surgery we believe necessity to follow three arrangements make more complete.This study presents correlations descriptions based on forensic medicine concepts research, literature review, proposal of an integration classic concept consent.In IC complete. Integrate information already present with data surgeon's experience RS, number procedures department regional map expertises...
Robotic surgery (RS) technology has undergone rapid growth in the surgical field since its approval. In clinical practice, failure of robotic procedures mainly results from a surgeon's inability or to device malfunction. We reviewed literature estimate impact this second circumstance RS and consequent legal implications. According data literature, malfunction is rare. believe it necessary complement training with technical understanding devices.
The COVID-19 pandemic is having a deep impact on emergency surgical services, with significant reduction of patients admitted into units world widely. Reliable figures this have not been produced yet. Our international audit aimed at giving precise snapshot the absolute and relative changes admissions outbreak pandemic.Datasets as general emergencies 45 internationally distributed during months March April 2020 (Covid-19 outbreak) were collected compared those same 2019 (pre-Covid-19)....
Pancreatic ductal adenocarcinoma (PDAC) poses significant clinical challenges, often presenting as unresectable with limited biopsy options. Here, we show that circulating tumor cells (CTCs) offer a promising alternative, serving "liquid biopsy" enables the generation of in vitro 3D models and highly aggressive vivo for functional molecular studies advanced PDAC. Within retrieved CTC pool (median 65 CTCs/5 mL), identify subset content 8.9%) CXCR4
The COVID19 pandemic had a deep impact on healthcare facilities in Italy, with profound reorganization of surgical activities. Italian ColoRectal Anastomotic Leakage (iCral) study group collecting 43 centers experienced colorectal surgery from multiple regions performed quick survey to make snapshot the current situation. A 25-items questionnaire was sent principal investigators iCral group, questions regarding qualitative and quantitative aspects activity before after outbreak. Two-thirds...
It is common to observe a gap between the day on which discharge criteria are reached and actual of after colorectal surgery. The aim this study understand reasons for difference its clinical impact overall length stay (LOS). All patients enrolled in prospective iCral3 were analyzed regarding any reason "fit discharge" (FFD) "actual (AD) dates. association LOS whole population was then assessed through multivariate regression model including other confounding variables. analysis included...
Abstract To compare the results of Minimally Invasive Esophagectomy performed with a Fully Robot-Assisted technique (F-RAMIE) and Hybrid approach laparoscopic abdominal phase (H-RAMIE). Multicentric retrospective analysis patients who underwent F-RAMIE H-RAMIE between 2018 2023. The primary endpoint was rate postoperative complications, secondary endpoints were clinical outcomes, oncological costs. Survival analyses calculated according to Kaplan–Meier method. economic evaluation included...
Background: Almost 30% of patients with rectal cancer (RC) who submit to comprehensive treatment experience relapse. Surveillance plays a leading role in early detection. The landmark approach provides more flexible and dynamic framework for survival prediction. Objective: This large retrospective study aims develop machine learning algorithm profile the patient prognosis, especially risk onset RC relapse after curative resection. Methods: A cohort 2450 were analyzed using analysis. Model...
Abstract Objectives This study aims to evaluate the clinical impact of introducing an Enhanced Recovery After Surgery (ERAS) protocol in management patients undergoing cytoreductive surgery (CRS), with or without hyperthermic intraperitoneal chemotherapy (HIPEC). By addressing a population at high risk postoperative complications and delayed recovery, seeks determine whether ERAS can improve short-term outcomes, optimize perioperative care, promote faster safer recovery standardized,...
Abstract Coronavirus Disease-19 (COVID-19) outbreak has significantly burdened healthcare systems worldwide, leading to reorganization of services and reallocation resources. The Italian Society for Study Esophageal Diseases (SISME) conducted a national survey evaluate changes in esophageal cancer management region severely struck by COVID-19 pandemic. A web-based questionnaire (26 items) was sent 12 SISME units. Short-term outcomes resections performed during the lockdown were compared with...
Abstract Background Fluorescence-guided visualization is a recently proposed technology in colorectal surgery. Possible uses include evaluating perfusion, navigating lymph nodes and searching for hepatic metastases peritoneal spread. Despite the absence of high-level evidence, this technique has gained considerable popularity among surgeons due to its significant reliability, safety, ease use relatively low cost. However, actual daily clinical practice not been reported date. Methods This...
Since most anastomoses after left-sided colorectal resections are performed with a circular stapler, any technological change in stapling devices may influence the incidence of anastomotic adverse events. The aim present study was to analyze effect three-row stapler on leakage and related morbidity resections.