A5101832781- Neurobiology and Insect Physiology Research
- Cellular transport and secretion
- Plant nutrient uptake and metabolism
- Cellular Mechanics and Interactions
- Genetics, Aging, and Longevity in Model Organisms
- Retinal Development and Disorders
- Cardiomyopathy and Myosin Studies
- Advanced MRI Techniques and Applications
- Physiological and biochemical adaptations
- Rice Cultivation and Yield Improvement
- Medicinal Plants and Neuroprotection
- Muscle Physiology and Disorders
- Functional Brain Connectivity Studies
- Plant and Biological Electrophysiology Studies
- GABA and Rice Research
- Plant Molecular Biology Research
- Crop Yield and Soil Fertility
- Soil Carbon and Nitrogen Dynamics
- Plant Micronutrient Interactions and Effects
- Aluminum toxicity and tolerance in plants and animals
- Advanced Neuroimaging Techniques and Applications
Nanjing Forestry University
2024
Southeast University
2018-2023
Tang Du Hospital
2021
Air Force Medical University
2021
China Agricultural University
2017-2019
Institute of Life Sciences
2017
Neuroligins are postsynaptic adhesion molecules that essential for specialization and synaptic function. But the underlying molecular mechanisms of neuroligin functions remain unclear. We found Drosophila Neuroligin 1 (DNlg1) regulates structure function through WAVE regulatory complex (WRC)-mediated actin reorganization. The disruption DNlg1, DNlg2, or their presynaptic partner neurexin (DNrx) led to a dramatic decrease in amount F-actin. Further study showed but not DNlg2 DNlg3, directly...
Although many members encoding different ammonium- and nitrate-transporters (AMTs, NRTs) were identified functionally characterized from several plant species, little is known about molecular components for NH4+- NO3- acquisition/transport in tobacco, which often used as a model biological studies besides its agricultural industrial interest. We reported here the first identification tobacco (Nicotiana tabacum) of nine AMTs four NRTs, are respectively divided into (AMT1/2/3/4) two (NRT1/2)...
Formation and plasticity of neural circuits rely on precise regulation synaptic growth. At Drosophila neuromuscular junction (NMJ), Bone Morphogenetic Protein (BMP) signaling is critical for many aspects synapse formation function. The evolutionarily conserved retromer complex its associated GTPase-activating protein TBC1D5 are regulators membrane trafficking cellular signaling. However, their functions in regulating the NMJ less understood. Here, we report that required inhibition growth,...
Background: Methadone maintenance treatment (MMT) is widely used for heroin use disorder. Although its curative effect remarkable, there are problems associated with use. While previous studies have found that methadone may certain effects on cerebral white matter, gray matter (GM) and related neural networks unclear. This study aimed to observe the of long-term GM changes in networks. Methods: Patients receiving MMT disorder (N=50) were recruited. Longitudinal self-control was adopted,...
Neuroligins are transmembrane cell adhesion proteins well-known for their genetic links to autism spectrum disorders. can function by regulating the actin cytoskeleton, however factors and mechanisms involved still largely unknown. Here, using Drosophila neuromuscular junction as a model, we reveal that F-Actin assembly at NMJ is controlled through Cofilin signaling mediated an interaction between DNlg2 RACK1, not previously known work together. The deletion of displays disrupted...
Neurexin, a molecule associated with autism spectrum disorders, is thought to function mainly in neurons. Recently, it was reported that Neurexin also present muscle, but the role of muscle still poorly understood. Here, we demonstrate overexpression muscles effectively restored locomotor Drosophila neurexin mutants, while rescuing effects are observed within nervous. Notably, defects structure and caused by deficiency were similar those mutations dystroglycan, gene progressive muscular...