A5019329297- SARS-CoV-2 and COVID-19 Research
- Global Cancer Incidence and Screening
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Liver Disease Diagnosis and Treatment
- AI in cancer detection
- Pancreatitis Pathology and Treatment
- Digital Radiography and Breast Imaging
- Ovarian cancer diagnosis and treatment
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Machine Learning in Healthcare
- Autoimmune and Inflammatory Disorders Research
- Chronic Myeloid Leukemia Treatments
- Acute Lymphoblastic Leukemia research
- Alcoholism and Thiamine Deficiency
- Blood Coagulation and Thrombosis Mechanisms
- Cancer therapeutics and mechanisms
- Healthcare Policy and Management
- Health, Environment, Cognitive Aging
- CRISPR and Genetic Engineering
- Alcohol Consumption and Health Effects
- COVID-19 and healthcare impacts
- Housing, Finance, and Neoliberalism
- Genetic Associations and Epidemiology
- Forensic Toxicology and Drug Analysis
Nference (United States)
2021-2022
Office of Multidisciplinary Activities
2018-2021
Advocate Lutheran General Hospital
2018
Federal Reserve
2015
Federal Reserve Board of Governors
2015
Ospedale San Giovanni Bosco
1990
The highly contagious Delta variant of SARS-CoV-2 has become a prevalent strain globally and poses public health challenge around the world. While there been extensive focus on understanding amino acid mutations in variant's Spike protein, mutational landscape rest proteome (25 proteins) remains poorly understood. To this end, we performed systematic analysis all proteins from nearly 2 million genomes 176 countries/territories. Six missense viral life cycle-associated Membrane (I82T),...
Equitable vaccination distribution is a priority for outcompeting the transmission of COVID-19. Here, impact demographic, socioeconomic, and environmental factors on county-level rates COVID-19 incidence changes assessed. In particular, using data from 3142 US counties with over 328 million individuals, correlations were computed between cumulative rate change in 1 December 2020 to 6 June 2021, 44 different environmental, socioeconomic factors. This correlation analysis was also performed...
Abstract The highly contagious Delta variant of SARS-CoV-2 has emerged as the new dominant global strain, and reports reduced effectiveness COVID-19 vaccines against are concerning. While there been extensive focus on understanding amino acid mutations in ‘s Spike protein, mutational landscape rest proteome (25 proteins) remains poorly understood. To this end, we performed a systematic analysis all proteins from nearly 2 million genomes 176 countries/territories. Six highly-prevalent...
Abstract Efficient and equitable vaccination distribution is a priority for effectively outcompeting the transmission of COVID-19 globally. A recent study from Centers Disease Control Prevention (CDC) identified that US counties with high social vulnerability according to metrics such as poverty, unemployment, low income, no school diploma, have significantly lower rates compared national average 1 . Here, we build upon this analysis consider associations between county-level 68 different...
Résumé L'utilisation du “Metronidazole” dans les vaginites et uréthrites a étée, pendant des années, le sujet de recherches expériences seulement récemment presque par chance il été découvert que ce remède pourrait être un auxiliaire utile traitement l'alcoolisme chronique. Cet article est limitéà la description d'un seul cas d'alcoolisme chronique conclut avec théorie l'administration drogue provoqué chez malade une aversion progressive pour l'alcool quand, traitement, patient buvait...
Background: Joint swelling and tenderness are common in patients with systemic lupus erythematosus (SLE). Swollen to tender joint count ratio (STR) is an index originally used rheumatoid arthritis (RA) which assesses severity of disease activity based on 28 counts [1]. In RA, STR a predictor treatment response higher score indicating greater likelihood responding. Objectives: To characterize SLE real-world cohort as defined by STR. Methods: The OM1 Registry (OM1, Boston, MA) follows more...
INTRODUCTION: Recent advances in mammography screening demonstrate dual benefits of decreased recall rates and increased cancer detection. We describe findings from an ongoing learning health system whose goal is to develop personalized breast imaging pathways. METHODS: A cloud-based big data platform robust technology infrastructure are being used integrate transform EMRs, radiology management systems, tumor registries. The current study cohort includes 181,649 women (239,888 examinations)...
Introduction: Screening mammography is a key component of secondary prevention programs targeting reductions in breast cancer mortality. The early detection cancers facilitates treatment at more curable, locoregionally limited stage. We describe characteristics and outcomes women who had only one screening mammogram versus those annual or biennial screens. Methods: A cloud-based big data platform being used to integrate transform from electronic medical records, radiology management systems,...
Abstract Among patients with schizophrenia (SZ) and bipolar I disorder (BD-I) treated second-generation antipsychotics (SGAs), clinically-significant weight gain (CSWG) treatment interruptions (TIs) are challenges that may result in morbidity/mortality. CSWG TIs were assessed among who initiated oral SGAs of moderate-to-high risk (no exposure to index SGAs/first-generation for =12 months) using medical records/claims (OM1 Data Cloud; January 2013-February 2020). Outcomes included (=7%...
Background: Equitable vaccination distribution is a priority for outcompeting the transmission of COVID-19. A recent CDC study found that US counties with high social vulnerability – according to metrics such as poverty, unemployment and low income have significantly lower rates compared national average. We build upon this analysis assess impact demographic, socioeconomic, environmental factors on county-level COVID-19 incidence changes. Methods: Using data from 3,142 (with over 328 million...