A5088834699- Heparin-Induced Thrombocytopenia and Thrombosis
- Venous Thromboembolism Diagnosis and Management
- Peptidase Inhibition and Analysis
- Autoimmune Bullous Skin Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Pituitary Gland Disorders and Treatments
- Metastasis and carcinoma case studies
- Protease and Inhibitor Mechanisms
- Mycobacterium research and diagnosis
- Cancer Research and Treatments
- Histiocytic Disorders and Treatments
- Glioma Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- Viral-associated cancers and disorders
- IgG4-Related and Inflammatory Diseases
- Genetics, Bioinformatics, and Biomedical Research
- Blood groups and transfusion
- Cancer, Hypoxia, and Metabolism
- Cell Image Analysis Techniques
- Liver Disease and Transplantation
- Genetic factors in colorectal cancer
- Parvovirus B19 Infection Studies
- Neurofibromatosis and Schwannoma Cases
- Autoimmune and Inflammatory Disorders
- Meningioma and schwannoma management
Nference (United States)
2023
University of Southern California
2021
University of California, Los Angeles
2021
Thomas Jefferson University
2015-2019
Thomas Jefferson University Hospital
2015-2019
Jefferson University Hospitals
2016
Alpha-1 antitrypsin deficiency (AATD) is caused by mutations in SERPINA1, which encodes alpha-1 antitrypsin, a protease inhibitor (Pi). Individuals with AATD and the homozygous Pi*ZZ genotype have variable risk of progressive liver disease but influence comorbid lung poorly understood.To characterise patients (AATD-LD-Pi*ZZ) or without describe disease-related clinical events longitudinally.This was an observational cohort study Mayo Clinic Healthcare System (January 2000-September 2021)....
Heparin is one of the most widely prescribed medications. Cutaneous reactions distant to injection site are rare and under-reported in literature. We present an elderly man with history CNS lymphoma who underwent treatment a deep venous thrombosis enoxaparin subsequently developed well demarcated bullous lesions within days heparin initiation. The exact pathophysiology not understood. Hemorrhagic dermatosis cutaneous reaction that temporally associated initiation products. handful cases thus...
Metastases to the central nervous system are often multiple in number and typically favor gray-white matter junction. Collision tumors, defined as coexistence of two morphologically different such metastases a known pituitary adenoma (PA), exceedingly rare. Only few reported cases PA exist literature.The authors present case 64-year-old man with history stage IV metastatic melanoma who was found have hypermetabolic activity sellar region on surveillance positron emission tomography. On...
Abstract Objectives Massive fetomaternal hemorrhage (FMH) is rare and reported to be the cause in approximately 3% of all fetal deaths. Maternal management massive FMH includes prevention Rh(D) alloimmunization Rh(D)-negative mothers by administration immune globulin (RhIG). Methods We describe a case 30-year-old O-negative, primigravida woman who presented at 38 weeks gestation with decreased movements. She underwent an emergency cesarean section delivered O-positive baby girl died shortly...
Kaposi sarcoma is a malignant vascular tumor consisting of multiple clinical subtypes and varying histopathologic patterns. We report case 53-year-old African-American male with HIV/AIDS who presented times skin nodules, pain, edema in his lower extremities, secondary to recurrent sarcoma. The patient was treated two courses liposomal doxorubicin improvement, but symptoms recurred third time. A biopsy specimen one the nodules showed prominent neoplastic cells epithelioid morphology, some...
The patient is a 64 year old man with active primary central nervous system B-cell lymphoma who was hospitalized for management of right lower extremity traumatic injury complicated by calf hematoma. During the hospital stay, diagnosed provoked left deep vein thrombosis (DVT) and treated initially therapeutic dosing enoxaparin. Five days after low molecular weight heparin (LMWH) initiation, gradual development tense, well-circumscribed bullae were noted to appear on his arms hands...
595 Background: CRCs arise through distinct mutations, including in APC pathway leading to tubular adenomas (TAs); BRAF, with epigenetic silencing of CDX2, serrated (SAs); and the DNA mismatch repair machinery driving microsatellite instability (MSI). The involves loss hormone guanylin, tumor suppressing receptor GUCY2C. Indeed, oral replacement is an emerging strategy reactivate GUCY2C prevent CRC. Moreover, retained expression by tumors arising from TAs has established as a therapeutic...
Inflammatory pseudotumor (IPT) is a rare benign mass forming lesion that has been reported in virtually every organ, and can closely mimic spindle cell neoplasms. Mycobacterial (MSP) represents small proportion of IPT the lymph node, which occur immunocompromised patients, posing diagnostic challenge. We report three cases MSP involving two AIDS patients who presented with generalized lymphadenopathy, one immunosuppressed patient mediastinal mass. Biopsy these revealed effaced architecture...