A5005498215- Ophthalmology and Visual Impairment Studies
- Visual perception and processing mechanisms
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Neural dynamics and brain function
- Corneal surgery and disorders
- Nanoplatforms for cancer theranostics
- Supramolecular Self-Assembly in Materials
- Spatial Neglect and Hemispheric Dysfunction
- Hydrogels: synthesis, properties, applications
- Multisensory perception and integration
- Action Observation and Synchronization
- Neural and Behavioral Psychology Studies
- Ocular Oncology and Treatments
- Corneal Surgery and Treatments
- Family and Disability Support Research
- Olfactory and Sensory Function Studies
- Photochromic and Fluorescence Chemistry
Affiliated Eye Hospital of Wenzhou Medical College
2019-2023
Wenzhou Medical University
2017-2023
Intraocular cancers such as retinoblastoma and uveal melanoma will induce severe vision loss or even death. Herein, a versatile nanocomposite thermogel based on hexanoyl glycol chitosan (HGC) mesoporous polydopamine nanoparticles (MPDA NPs) was designed for potential use an intraocular "drug depot" the treatment of tumors. The integrated HGC-MPDA showed reversible sol-gel transition property well injectable in-situ gelation abilities. incorporated MPDA NPs endowed with outstanding NIR...
We investigate temporal synchrony within one eye and between both eyes in adults with amblyopia.Eight adult amblyopes (range, 19.88-27.81 years old; median, 22.86 old) 12 age-matched normal vision 21.2-50.30 23.78 participated the experiment. showed two pairs of Gaussian blobs flickering at 1 Hz as visual stimuli, pair same phase modulation (i.e., reference) another a distinct signal). employed constant stimuli method to measure minimum degree (temporal threshold), which participants were...
Oxidative stress is considered as a major factor causing retinal pigment epithelium (RPE) dysfunction and finally leading to diseases such age-related macular degeneration (AMD). Developing hydrogels for RPE cell delivery, especially those with antioxidant feature, emerging promising approach AMD treatment. Herein, readily prepared alginate-based hydrogel was developed serve cytoprotective agent cells against oxidative damage. Alg-BOB synthesized via conjugation of benzoxaborole (BOB) the...
To assess interocular delays in amblyopes with stereopsis and to evaluate the relationship between clinical characteristics.Twenty (median, 400 arcseconds) 20 controls normal or corrected visual acuity (≤0 logMAR) (≤60 participated. Using a rotating cylinder defined by horizontally moving Gabor patches, we produced spontaneous Pulfrich phenomenon order determine delays, that is, phase difference at which ambiguous motion plane was perceived. Two spatial frequencies-a low (0.95 cycles/degree...
BackgroundThe aim was to compare the repeatability of subjective accommodative amplitude (AA) measurements obtained using modified push‐up and minus‐lens methods determine agreement with objective AA by an autorefractor.MethodsThe right eyes 47 adults aged 22–30-years (mean 25.1 ± 1.9) were measured methods. Subjective AAs first sustained blur unreadable criteria average three consecutive measurements. Measurements simulated minus lens open‐field autorefractor. The two among different...
Abstract Purpose To evaluate whether temporal synchrony processing deficits remain when normal visual acuity is restored in adults with unilateral anisometropic amblyopia. Methods We recruited 14 clinically treated amblyopes (mean age 23.17 ± 2.53 years) best‐corrected ≤ 0.1 logMAR and 15 age‐matched emmetropes 24.40 1.92 vision to participate our experiment. presented two pairs of flicking Gaussian dots (1 Hz) as stimuli: one pair was synchronous (reference), the other asynchronous...
Purpose: The purpose of this study was to present our investigation the influence reduced monocular luminance on and dichoptic temporal synchrony processing in healthy adults. Methods: Ten adults with normal or corrected visual acuity participated psychophysical study. threshold (experiment 1), 2), binocular 3) viewing configurations obtained from each observer. Four flickering Gaussian dots (one synchronous one asynchronous pair two dots) were displayed, which observers asked identify pair....
Studies on binocular combination and rivalry show that short-term deprivation strengthens the contribution of deprived eye in vision. However, whether monocular affects temporal processing per se is not clear. To address this issue, we conducted a study to investigate effect dichoptic synchrony. We tested ten adults with normal vision patched their dominant an opaque patch for 2.5 h. A synchrony paradigm was used measure if thresholds change as result pattern deprivation. In paradigm,...
Natural mucus-inspired hydrogels have recently garnered significant attention in the fields of drug delivery and tissue engineering. Herein, we successfully prepared mucin-based with self-repairing capability antioxidant activity by...
Purpose: Recently, Lunghi et al showed that amblyopic eye's visual acuity per se after 2 months of occlusion therapy could be predicted by a homeostatic plasticity, i.e., the temporary shift perceptual eye dominance observed 2-hour monocular deprivation, in children with anisometropic amblyopia(Lunghi al., 2016). In this study, we assess whether improvement measured plasticity. Methods: Seven (6.86 ± 1.46 years old; SD) amblyopia participated study. All patients were newly diagnosed and had...
To investigate changes in blur detection sensitivity children using orthokeratology (Ortho-K) and explore the relationships between thresholds (BDTs) aberrations accommodative function.Thirty-two aged 8-14 years old who underwent Ortho-K treatment participated completed this study. Their BDTs, aberrations, responses (ARs) were measured before after a month of treatment. A two forced-choice double-staircase procedure with varying extents three images (Tumbling Es, Lena, Street View) was used...
Objective: To study the correlation between wavefront aberrations and refractive conditions, corneal curvature, axial length in schoolchildren with low myopia. Methods: This was a case series study. One hundred eighty 8 to 13 years old, spherical equivalent (SE) of -0.50- -3.00 D, were recruited. Refractive error, calculated as SE, (AL), curvature radius (R, flat meridian—— R1, steep R2) measured by IOLMaster, WASCA Hartmann-Shack aberrometer. Multiple linear regression used analyze...
Abstract Purpose Recently, Lunghi et al showed that amblyopic eye’s visual acuity per se after 2 months of occlusion therapy could be predicted by a homeostatic plasticity, i.e., the temporary shift ocular dominance observed 2-hour monocular deprivation, in children with anisometropic amblyopia(Lunghi al., 2016). In this study, we assess whether improvement eye measured plasticity. Methods Seven (6.86 ± 1.46 years old; SD) amblyopia participated study. All patients were newly diagnosed and...