A5102769136- Visual perception and processing mechanisms
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Corneal surgery and disorders
- Spatial Neglect and Hemispheric Dysfunction
- Video Surveillance and Tracking Methods
- Vestibular and auditory disorders
- Olfactory and Sensory Function Studies
- Neural and Behavioral Psychology Studies
- Neuroscience and Neuropharmacology Research
- Anomaly Detection Techniques and Applications
- Neural dynamics and brain function
- Human Pose and Action Recognition
- Cognitive Abilities and Testing
- Neurobiology and Insect Physiology Research
- Optical Imaging and Spectroscopy Techniques
Affiliated Eye Hospital of Wenzhou Medical College
2018-2023
Wenzhou Medical University
2018-2023
Recent laboratory findings suggest that short-term patching of the amblyopic eye (i.e., inverse occlusion) results in a larger and more sustained improvement binocular balance compared with normal controls. In this study, we investigate cumulative effects occlusion adults old children amblyopia. This is prospective cohort study 18 amblyopes (10-35 years old; 2 strabismus) who have been subjected to hours/day for months. Patients required refractive correction or whose needed updating were...
Amblyopia (lazy eye) is a neurodevelopmental disorder of vision with no ocular pathology. The loss in the amblyopic eye assumed to be main deficit amblyopia, which has resulted visual acuity (VA) being primary outcome measure for treatment. Here we used binocular orientation combination task quantitatively assess status by measuring balance. We set out determine whether amblyopes who reach acuity-based end point have residual imbalance. Our results suggest that even regained normal deficits...
The adult human visual system maintains the ability to be altered by sensory deprivation. What has not been considered is whether internal neural states modulate sensitivity short-term monocular In this study we manipulated state and reported changes in intrinsic oscillations with a patched eye open or closed. We investigated influence of open/eye closure on unpatched eye's contrast ocular dominance (OD) shifts induced results demonstrate that only baseline but also extent which can undergo...
How to precisely quantify the binocular eye balance (i.e., contribution that each makes percept) across a range of spatial frequencies using combination task, is an important issue in both clinical and basic research. In this study, we aimed compare precision orientation paradigm with standard phase measuring at low high frequencies. Nine normal adults (average age: 24.6 ± 2.0 years old) participated. Subjects viewed LED screen dichoptically polarized glasses dark room. The method constant...
Purpose: To assess the role of spatial frequency on binocular imbalance in combination adults with amblyopia. Methods: Ten amblyopes (23 ± 4.9 [SD] years old; one deprivation, two mixed, seven anisometropia patients) and 10 age-matched normal 2.3 old) participated. The interocular contrast ratio (fellow eye/amblyopic eye, i.e., balance point [BP]) that resulted an equal contribution both eyes was measured using a orientation task at 0.5, 1, 2, 4 cycles per degree (c/d). extent quantified as...
Purpose: To determine if benefits from occlusion therapy are due to decreased suppression the fellow eye in children with amblyopia. Methods: Ten newly diagnosed amblyopes (7.2 ± 1.4 years old), two strabismus and eight anisometropia, participated. Patients were first given a 2-month period of refractive adaptation, followed by (i.e., patching their an opaque patch for 4 hours/day). Visual acuity amblyopic interocular measured before after 0.5, 1, 2, 6 months therapy. We quantified binocular...
We investigate temporal synchrony within one eye and between both eyes in adults with amblyopia.Eight adult amblyopes (range, 19.88-27.81 years old; median, 22.86 old) 12 age-matched normal vision 21.2-50.30 23.78 participated the experiment. showed two pairs of Gaussian blobs flickering at 1 Hz as visual stimuli, pair same phase modulation (i.e., reference) another a distinct signal). employed constant stimuli method to measure minimum degree (temporal threshold), which participants were...
Interocular suppression was quantified by the interocular luminance difference that needed when two eyes were balanced in discriminating a black-white stripe formed butterfly stimulus, which dichoptically presented through polarized glasses. Stronger found amblyopes than controls at both near (33 cm, 0.95 ± 1.00 vs. 0.14 0.18, p < .001) and far (5 m, 2.18 0.97 0.24 0.16, viewing distances. The significantly correlated with visual acuity difference, of amblyopic eye, Worth-4-Dot test, stereo...
To assess interocular delays in amblyopes with stereopsis and to evaluate the relationship between clinical characteristics.Twenty (median, 400 arcseconds) 20 controls normal or corrected visual acuity (≤0 logMAR) (≤60 participated. Using a rotating cylinder defined by horizontally moving Gabor patches, we produced spontaneous Pulfrich phenomenon order determine delays, that is, phase difference at which ambiguous motion plane was perceived. Two spatial frequencies-a low (0.95 cycles/degree...
Amblyopia is a visual disorder that originates from the brain. It exhibits no pathology in eye. Studies have shown measuring both acuity and binocular balance for assessing amblyopia could be more helpful. However, tests measure are time-consuming, often exceeding 30 min. Their long test durations prevent them being used clinic. For this reason, we developed quick (i.e., about 7 min) precise tool quantitatively measures of patients with amblyopia. The new can capture imbalance typically...
Amblyopia is a visual impairment that perturbs binocular balance at high spatial frequencies in favor of the fellow eye. Studies reveal amblyopes who had been treated with monocular therapies still show imbalance. Binocular achieved when both eyes' inputs are weighed equally. A reduced light can diminish dimmed eye's weight combination. In this study, we examined if across could be improved by reducing luminance eye adult amblyopes. By doing so, relieved their imbalance frequencies. Also,...
Purpose: The current understanding of binocular processing is primarily derived from static spatial visual perception: this leaves the role temporal information unclear. In study, we addressed gap by testing effect alternating flicker on in adults with abnormal vision. Our goal was to determine which frequency optimally balanced input both eyes. Methods: We took measurements four groups human adults: 10 normal individual's nondominant eye covered a 2% neutral density filter (aged 25.60 ±...
Action video gaming can promote neural plasticity. Short-term monocular patching drives plasticity in the visual system of human adults. For instance, short-term 0.5-5 h briefly enhances patched eye's contribution binocular vision (i.e., ocular dominance plasticity). In this study, we investigate whether action influence adults with normal vision. We measured participants' eye using a phase combination task before and after 2.5 patching. Participants were asked to play games, watch game...
Abstract Recent laboratory finding suggest that short-term patching the amblyopic eye (i.e., inverse occlusion) results in a larger and more sustained improvement binocular balance compared with normal controls. In this study, we investigate cumulative effects of occlusion adults old children amblyopia. A prospective cohort study 18 amblyopes (10-35 years old; 3 strabismus) who have been subjected to 2 hours/day for months. Patients required refractive correction or whose needed updating...
Amblyopia is a visual disorder that originates from the brain. It exhibits no pathology in eye. Studies show balance between both eyes heavily impaired - selectively at higher spatial frequencies amblyopic patients and those whose acuity have recovered longitudinal treatment for their childhood amblyopia. These findings raise question of whether solely examining acuity, as it so standard clinical practice, truly informative. They suggest measuring binocular assessing amblyopia could be more...
Studies have shown that short-term monocular deprivation induces a shift in sensory eye dominance favor of the deprived eye. Yet, how modulates across spatial frequency is not clear. To address this issue, we conducted study to investigate dependence effect on test frequency. Ten healthy young adults (age: 24.7 ± 1.7 years, four males) with normal vision participated. We their dominant translucent patch for 2.5 h. The interocular contrast ratio (dominant eye/non-dominant eye, i.e., balance...
Abstract The adult human visual system can exhibit a degree of neuroplastic change under the right conditions which has implications for future treatments to recover vision loss that have occurred in infancy. exogenous factors promote been focus psychophysical, electrophysiological and neuroimaging research over last decade. What not considered is importance endogenous factors. In this study we modulate neural oscillations determines internal state demonstrate play critical role only...