- Ophthalmology and Eye Disorders
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Vestibular and auditory disorders
- Retinal Diseases and Treatments
- Pituitary Gland Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Migraine and Headache Studies
- Corneal surgery and disorders
- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Advanced Neuroimaging Techniques and Applications
- Cerebrospinal fluid and hydrocephalus
- Botulinum Toxin and Related Neurological Disorders
- Visual perception and processing mechanisms
- Patient Satisfaction in Healthcare
- Hearing, Cochlea, Tinnitus, Genetics
- Hemispheric Asymmetry in Neuroscience
- Sympathectomy and Hyperhidrosis Treatments
- Phytochemistry and Biological Activities
- Ophthalmology and Visual Health Research
- Health Systems, Economic Evaluations, Quality of Life
- Glutathione Transferases and Polymorphisms
- Corneal Surgery and Treatments
- Healthcare and Venom Research
Affiliated Eye Hospital of Wenzhou Medical College
2016-2025
Wenzhou Medical University
2016-2025
National Clinical Research Center for Digestive Diseases
2021-2023
University of Warmia and Mazury in Olsztyn
2022
Charité - Universitätsmedizin Berlin
2022
Instituto Politécnico de Lisboa
2022
Universidade Nova de Lisboa
2022
Hospital Posadas
2022
Sun Yat-sen University
2021-2022
Fujian Women and Children Hospital
2022
Purpose To identify the relationship between increase in axial length (AL) and height school-age children explore influence of refractive status on such a relationship. Methods In this 5-year cohort study, 414 Chinese (237 boys) aged 6–9 years (mean 7.12) underwent measurements annually. AL was measured using Lenstar; with standing, without shoes; refraction subjective cycloplegia. Participants were divided according to status: persistent emmetropia, myopia, newly developed myopia. The...
To explore whether there is a difference in postoperative extraocular muscle (EOM) remodeling between 1-month-old and 3-month-old rabbits. Recession (n = 16) resection were performed on the right superior rectus (SR) muscles of SR tissues harvested 1 4 weeks post-surgery for each group), mid-belly sections used to assess myosin heavy chain (MyHC) isoform expression (fast 2X, embryonic, neonatal MyHCs), activated satellite cells (SCs), centrally nucleated myofibers. Age-matched unoperated...
To investigate the longitudinal changes in myopia from onset to stabilization school-aged children with single-vison lenses (SVLs).The medical records of patients wearing SVLs long-term follow-up data between 2006 and 2016 were retrospectively reviewed. The who 6-10 years old at initial visit 16 last assessment included analysed. periods progression evaluated by plotting fitted curves spherical equivalent (SE).Seven hundred seventy-three (median age 9 years) accessed over an average 7 (IQR,...
With increasing axial length and myopia progression, the micro-structure of retina choroid gradually changes. Our study describes longitudinal changes in retinal choroidal thickness school-aged children with explores relationship between progression.An exploratory analysis a randomized trial was performed. Children (n = 168, aged 7 to 12 years) from - 0.75 dioptre (D) 4.00 D were enrolled this prospective study. Cycloplegic refraction, (AL), thicknesses measured at baseline 1- 2-year...
To evaluate the status of and factors associated with long-term health-related quality life (HRQOL) in adult patients strabismus following corrective surgery.Prospective cross-sectional study. A total 122 adults who underwent surgery were followed up for at least 1 year recruited. Pre- post-operative HRQOL evaluated using Chinese version Adult Strabismus 20 (AS-20). Demographics clinical characteristics recorded. Eighty-nine age-matched, normal individuals without a history recruited as...
To investigate binocular visual deficits at low to high spatial frequencies in patients with intermittent exotropia (IXT) after surgical correction, using the orientation combination task.
To evaluate whether clinical measures of postoperative binocular functions could predict the long-term stability ocular alignment in children with intermittent exotropia. A retrospective study was performed thirty-nine (median: 7 years) who have been surgically treated from exotropia without overcorrection (less than 10 prism diopters [pd] exodeviation at 1 month postoperatively). Angles deviation and were measured preoperatively month, 6 months, final follow-up visit (≥24 months)...
Background: To assess the clinical effectiveness of orthoptic therapy in postoperative stabilisation and rehabilitation binocular function children with intermittent exotropia (IXT) after surgery. Methods: This was a prospective, parallel, randomised controlled trial. A total 136 IXT patients (aged from 7 to 17 years) who had been successfully corrected at 1 month surgery were enrolled this study, 117 (58 controls) completed 12-month follow-up visit. The primary outcome established as...
Interocular suppression was quantified by the interocular luminance difference that needed when two eyes were balanced in discriminating a black-white stripe formed butterfly stimulus, which dichoptically presented through polarized glasses. Stronger found amblyopes than controls at both near (33 cm, 0.95 ± 1.00 vs. 0.14 0.18, p < .001) and far (5 m, 2.18 0.97 0.24 0.16, viewing distances. The significantly correlated with visual acuity difference, of amblyopic eye, Worth-4-Dot test, stereo...
Purpose To study the longitudinal rehabilitation of binocular visual function in adolescent intermittent exotropia (IXT) after successful surgery and compare results with those a normal population. The role ocular alignment stability was also evaluated postoperatively. Methods In this prospective study, 30 adolescents IXT successfully corrected 1 month were followed for 12 months, children vision enrolled as controls. Stereopsis, fusional vergence amplitude, sensory fusion, accommodative...
Intermittent exotropia (IXT) is the most common type of in China. Surgery usually required to align eye deviation maintain or obtain better binocular visual function. However, there a high rate exodrift recurrence surgically treated patients. Orthoptic therapy sometimes recommended for IXT patients after surgery. lack high-quality randomized controlled trials prove that orthoptic could be an effective supplement surgical treatment The main purpose this study test clinical effectiveness...
Abstract Reading speed in intermittent exotropia (IXT) children has been minimally examined. This study assessed reading school-age with IXT and determined clinical characteristics of that impacted their ability. We compared the 63 (10–14 years) to 44 age-matched normal counterparts. In addition, correlation between were evaluated. The was 231 ± 51 CPM, while counterparts 257 33 CPM. Age, gender found be factors associated IXT. After adjusting for age gender, we a significant LogTNO group...
Purpose: To determine binocular summation of surgically treated intermittent exotropia (IXT) patients by measuring the contrast threshold. Methods: We recruited 38 IXT aged 8-24 years and 20 age-matched healthy controls. All participants had normal or corrected-to-normal visual acuity (Snellen ≥ 20/20) in both eyes. The undergone surgery at least a year prior to study. Twenty-one them obtained good alignment 17 experienced recurrence exotropia. measured observers' monocular sensitivities...
Purpose This study aimed to investigate the outcomes of Botulinum toxin A (BTA) injection into inferior oblique (IO) muscle for management unilateral acute acquired superior palsy (SOP) and evaluate changes in health-related quality life post-injection using Adult Strabismus-20 (AS-20) questionnaire. Methods prospective cohort was performed patients with SOP who received BTA injections. Four units were injected ipsilateral IO muscle. Ocular examinations pre-and post-injection, including...
Objective: To evaluate the effects of corrective surgery in adult strabismic patients with visual deficits and stability postoperative alignments. Methods: Retrospective study. Alignment binocular function were evaluated (best acuity (BCVA) <0.3 one or both eyes) at least 6 months follow-up. The results these compared to those normal nearly vision (BCVA ≥ 0.6 worse eye) matched by type strabismus, magnitude deviation, age time surgery, length before final
In Brief Purpose: To assess macular microstructure in eyes with tilted disk syndrome (TDS) and determine the relationship between TDS foveal morphology visual function. Methods: Twenty-six from 19 children (aged 5∼15 years) a spherical equivalent refraction (SER) of −3.1 ± 1.3 diopter (D) 28 control 14 7∼12 SER −3.0 0.7 D were recruited. Horizontal vertical optical coherence tomography scans through fovea produced images that segmented into eight intraretinal layers. Thicknesses total retina...
Objective To observe the macular choroidal and retinal pigment epithelium (RPE) thickness in tilted disc syndrome (TDS).Methods This is a descriptive study.Thirty eyes of 22 TDS patients (TDS group) 30 15 normal subjects (control were analyzed.Among group,there 8 males (11 eyes) 14 females (19 eyes),the average age was (9.00±2.78) years old.The best corrected visual acuity (BCVA) 0.3-1.0,and spherical equivalent degree (-3.44±2.22) DS.Among control (16 7 (14 (9.33±1.11) ≥1.0,and (-3.18 ±...
Abstract Purpose Intermittent exotropia (IXT) is the most common form of childhood exotropia. Currently, controversies exist regarding its management and non-surgical options in particular. This study reports clinical opinions preferences on among practitioners China. The within between ophthalmologists optometrists were also compared. Design Cross-sectional survey study. Methods An online was developed distributed through professional bodies. conducted from July 25 th to August 3 rd , 2019....
Purpose: To assess the potential of a health examination center-based screening model in improving service for uncorrected refractive error. Methods: Individuals aged ≥18 years undergoing routine physical examinations at tertiary hospital northeast China were invited. Presenting visual acuity, noncycloplegic autorefraction, noncontact tonometry, fundus photography, and slit-lamp performed. Refractive error was defined as having spherical equivalent ≤ -0.75 D or ≥ +1 considered combined with...
This study reports clinical opinions and preferences on the non-surgical management of intermittent exotropia (IXT) among practitioners in China.An online survey was developed distributed through professional bodies. The conducted from July 25th to August 3rd, 2019. A total 300 ophthalmologists 188 optometrists responded.Of 488 participants, 257 (53%) considered fusion defects as main cause IXT, 299 (61%) took IXT a progressive disorder. Two hundred seventy-one (56%) participants orthoptic...
Objective: To investigate the long-term clinical effects and postoperative changes in children with intermittent exotropia. Methods: In this retrospective case series study, 139 exotropia who underwent strabismus surgery were followed for more than 12 months. Distant near squint angles as well binocular visual function parameters collected preoperatively, at 1 week month postoperatively, last follow-up. Independent sample t-tests used to compare distant between pre- periods....