A5038244967- Amyloidosis: Diagnosis, Treatment, Outcomes
- Intracerebral and Subarachnoid Hemorrhage Research
- Alzheimer's disease research and treatments
- Acute Ischemic Stroke Management
- Vasculitis and related conditions
- Agriculture and Rural Development Research
- Autoimmune Neurological Disorders and Treatments
- Stroke Rehabilitation and Recovery
- Health, Medicine and Society
- Inflammasome and immune disorders
- Venous Thromboembolism Diagnosis and Management
- French Urban and Social Studies
- Renal Diseases and Glomerulopathies
- Immunodeficiency and Autoimmune Disorders
- Sarcoidosis and Beryllium Toxicity Research
- interferon and immune responses
- Aging, Elder Care, and Social Issues
- Retinal and Optic Conditions
- Cerebrovascular and genetic disorders
- African Studies and Ethnography
- Chronic Lymphocytic Leukemia Research
- Salivary Gland Disorders and Functions
- Organizational Management and Leadership
- Inflammatory Myopathies and Dermatomyositis
- Neurological Complications and Syndromes
Sorbonne Université
2015-2025
Pitié-Salpêtrière Hospital
2025
Assistance Publique – Hôpitaux de Paris
2010-2024
Centre Hospitalier Universitaire de Tours
2024
Université de Rouen Normandie
2024
Hôpital Saint-Antoine
2013-2023
Centre de Recherche Saint-Antoine
2018-2021
Délégation Paris 6
1992-2021
Inserm
2016-2021
Fondation de Rothschild
2020
Cerebral amyloid angiopathy-related inflammation (CAA-RI) and biopsy-positive primary angiitis of the CNS (BP-PACNS) have overlapping clinicoradiologic presentations. It is unknown whether clinical radiologic features can differentiate CAA-RI from BP-PACNS both diseases different relapse rates. The objectives this study were to compare presentations rates in patients with vs BP-PACNS.
To investigate in routine care the efficacy and safety of IV thrombolysis (IVT) with tenecteplase prior to mechanical thrombectomy (MT) patients large vessel occlusion acute ischemic strokes (LVO-AIS), either secondarily transferred after IVT or directly admitted a comprehensive stroke center (CSC).We retrospectively analyzed clinical procedural data treated 0.25 mg/kg within 270 minutes LVO-AIS who underwent brain angiography. The main outcome was 3-month functional independence (modified...
ABSTRACT Background To determine whether hierarchical unsupervised cluster analysis identifies a phenotypic distinction in adult patients with primary CNS vasculitis (PCNSV). Methods An agglomerative based on the Ward method was conducted, including 153 complete baseline characterization COVAC' registry. Results The identified two main clusters. In Cluster 1 ( n = 109 patients, 71%), more frequently had motor deficit p 0.039), ≥ acute brain infarct < 0.001), and intracranial stenosis CT...
This French multicenter retrospective cohort study aimed to describe the autoimmune manifestations (AIMs) associated with lymphoma among patients hospitalized between 2005 and 2016 in three University Hospitals. Among 2503 lymphoma, 108 (4.3%) had AIMs, mostly cytopenias (71.3%), neurological diseases (10.2%), kidney (6.5%), systemic vasculitis (5.6%) others. As compared 2395 without those AIMs were older (p = .01), more frequently B-cell chronic lymphocytic leukemia < .01) less diffuse...
Recent studies suggest that sleep disorders are present in two-thirds of patients with autoimmune encephalitis. In anti-Ma2 encephalitis, hypersomnia appears to be frequent. However, only few cases type 1 narcolepsy have been reported date We report 2 new secondary Patient 1, a 68-year-old man, had including attacks, cataplexy, abnormal Multiple Sleep Latency Tests and hypocretin-1 deficiency (< 50 ng/L) the cerebrospinal fluid (CSF), associated cerebellar syndrome. Anti-Ma2 antibodies were...
There is limited evidence on when to obtain a central nervous system (CNS) biopsy in suspected primary angiitis of the (PACNS). Our objective was identify which clinical and radiological characteristics were associated with positive PACNS. From multicentre retrospective Cohort Patients Primary Vasculitis CNS (COVAC), we included adults PACNS based or otherwise unexplained intracranial stenoses additional findings supportive vasculitis. Baseline compared between patients negative using...
Opening Paragraph On a souvent répété des cultures négro-africaines qu'elles étaient imprégnées de spiritualité sinon religiosité; pourtant, comme le remarquait dans un récent article Madame Calame-Griaule: ‘il serait faux croire que facteur religieux y joue rôle essentiel’; il se situe en réalité sur même plan les autres manifestations la vie sociale; concourt à construction cet ensemble fonctionnel constitue toute culture. C'est cette perspective nous voudrions tenter d'examiner comment...
Purpose The DAWN trial (Diffusion weighted imaging or CT perfusion Assessment with clinical mismatch in the triage of Wake-up and late presenting strokes undergoing Neurointervention Trevo) has demonstrated benefits thrombectomy patients unknown onset strokes, using automated software (RAPID) for measurement infarct volume. Because RAPID is not available all centers, we aimed to assess accuracy repeatability visual volume estimation by clinicians consequences decisions based on criteria....
To determine whether the ABC/2 method could accurately and reliably measure infarct volume guide thrombectomy decision in acute stroke cases presenting with late or unknown onset.
L’examen des fonctions cognitives peut être abordé selon deux approches : l’une, quantitative, repose sur l’utilisation de tests dépistage ; l’autre, qualitative, l’examen ciblé chaque fonction. L’approche quantitative entre dans une démarche pragmatique dépister rapidement un déficit qui pourra justifier la mise en place d’aides ou traitements. Nous présenterons trois et leur valeur diagnostique le test l’horloge, Mini Mental State Examination Montreal Cognitive Assessment. Cette approche...