The preclinical study aimed to compare the healing of segmental bone defects treated with biodegradable hyaluronic acid and tricalcium phosphate-based hydrogel established autologous spongioplasty. Another aim was evaluate as a scaffold for osteoinductive growth factor morphogenetic protein-2 (BMP-2) stem cells. conducted in an vivo animal model. A standardized rabbit model 15 mm long defect left radius used. total 40 animals were divided into 5 groups 8 individuals. In KO- (negative...

The purpose of this prospective controlled study was to compare healing quality following the implantation ultraporous<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M2"><mml:mrow><mml:mi>β</mml:mi></mml:mrow></mml:math>-tricalcium phosphate, containing either expanded autologous mesenchymal stromal cells (trial group, 9 patients) or<mml:math id="M3"><mml:mrow><mml:mi>β</mml:mi></mml:mrow></mml:math>-tricalcium phosphate alone (control patients), into femoral defects during...

This prospective study sought to evaluate the healing quality of implanted ultraporous β-tricalcium phosphate sown with expanded autologous mesenchymal stromal cells (MSCs) into femoral defects during revision hip arthroplasty. A total 37 osseous in patients were treated and evaluated concerning bone regeneration. Nineteen subjects received graft material serving as a carrier MSCs (the trial group A), nine only B) cancellous allografts control C). Clinical radiographic evaluations scheduled...

The aim of this study is to evaluate the results total hip arthroplasty in patients with Parkinson's disease during a period five years, focusing on assessment risks and benefits surgery. During we performed 14 (15 hips) disease. Patients were evaluated by subjective symptoms objective findings, focus use support while walking distance, severity before surgery at time last follow-up. postoperative period, following parameters assessed: length ICU stay, mobilization, complications, duration...

Periprosthetic fractures are the third most common reason for revision total hip arthroplasty. Surgical treatment of periprosthetic belongs to difficult procedures due extensive surgery, elderly polymorbid patients and high frequency other complications. The aim this study was evaluate results operatively treated femoral after We evaluated 47 in 40 (18 men 22 women) operated on between January 2004 December 2010. mean follow-up period 27 months (within a range 12–45 months). For clinical...

Introduction . The aim of the study was to compare clinical outcomes following elective and traumatic total hip arthroplasty in Parkinson’s disease patients. Materials Methods Ten patients with osteoarthritis comprise group (mean age at operation 74 years; mean follow-up 82 months). Thirteen femoral fracture 76 54 All were followed up 6 36 months postoperatively time latest follow-up. Results Despite significant improvement Merle d’Aubigné-Postel pain scores, disability related increased...

Abstract Bone marrow–derived cells represent a heterogeneous cell population containing haematopoietic stem and progenitor cells. These have been identified as potential candidates for use in therapy the regeneration of damaged tissues caused by trauma, degenerative diseases, ischaemia inflammation or cancer treatment. In our study, we examined model using whole‐body irradiation transplantation bone marrow ( BM ) HSC s) to study repair haematopoiesis, extramedullary haematopoiesis migration...

The present study compares the outcome of long cemented stem and revision uncemented used in periprosthetic femoral fractures. We propose that with a prosthesis does not compromise fracture healing.A consecutive series 37 patients, operated between 2010 2017, were enrolled retrospective analysis. A was implanted 21 patients (study group; age at operation: 63 to 89 years). distally tapered fluted 16 (control 35 77 clinical evaluated Merle d'Aubigné Postel scoring system. Standard radiographs...

Background Total hip (THA) or knee (TKA) arthroplasty is still a traumatic and challenging operation that induces inflammation, with particularly high risk of acute-phase reaction. The aim this study was to predict the likelihood implant-associated complications during preoperative postoperative course. Methods prospective observational, non-interventional patients diagnosed primary osteoarthrosis undergoing THA TKA period conducted. inflammatory malnutrition parameters were collected for...

Musculoskeletal infections remain a major complication in orthopedic surgery. The local delivery of antibiotics provides the high levels required to treat an infection without systemic toxicity. However, toxicity antibiotic carriers mesenchymal stem cells, as result both peak concentrations and type carrier, may be significant.To address this concern, elution kinetics vancomycin gentamicin from several commercially available impregnated by surgeon (10 ml each sterile carrier were manually...

PURPOSE OF THE STUDYThe aim of the study was to ascertain what proportion patients undergoing total knee arthroplasty (TKA) complain restricted joint motion, and investigate options for improvement this situation. MATERIALOur evaluation included a group 796 treated with TKA at our department in period from January 1, 1990, December 31, 2004.In all cases, condylar implant preservation posterior cruciate ligaments used. CONCLUSIONSRestricted motion after is difficult treat and, therefore,...

The authors present the case of a boy with congenital pseudoarthrosis right clavicle who met all clinical and auxologic criteria Prader-Willi's syndrome.Poor cooperation due to mental retardation was reason for primary conservative treatment.During this, deformity middle progressed, but without development subjective complaints functional deficit.At his 16 years, this cosmetic defect became unacceptable parents and, later than it is usually recommended, resection plate osteosynthesis...

The purpose of the study was to assess long-term behavior and incorporation bioactive oxyhydroxyapatite glass-ceramic used fill defects long bones after curettage bone cysts in 17 patients. method evaluation a three-phase scintigraphy combined with radiographic clinical evaluation. At mean follow-up 7 years, material had been completely incorporated. Mean uptake ratio 1.31±0.25 implantation metaphyseal region 2.07±0.62 diaphyseal (P<0.05). 1.40±0.30 patients without persistent pain 2.07±0.69...

Adolescent hallux valgus (HV) is a progressive deformity of adolescent age consisting metatarsus primus varus and valgus. It has high recurrence rate after conventional surgical correction. Ten feet in nine patients (two males, seven females) were treated surgically with the Peterson Newman bunion procedure, minimum follow-up one year. During final all these had no complaints pain, joint stiffness or limping. Even though some mild loss range movements at MTPjoints 4-6 degrees compared to...

The aim of this study is to present our experience with two-stage reimplantation in the management infected hip arthroplasty. Between January 1993 and December 2001 replacement total arthroplasty two stages was performed 18 patients. There were 7 male 11 female patients average age 62 years. mean follow-up after revision 3.5 postoperative Harris Hip Score averaged 78 (50-96) points. None had a recurrence infection. Two-stage reconstruction preferred one-stage exchange at department because...