Lisa Holland
- Lipoproteins and Cardiovascular Health
- Connective tissue disorders research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Parathyroid Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Helicobacter pylori-related gastroenterology studies
- Fibroblast Growth Factor Research
- Vitamin D Research Studies
- Cerebrovascular and Carotid Artery Diseases
- HIV-related health complications and treatments
- Coronary Interventions and Diagnostics
- Gastrointestinal Bleeding Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Cardiovascular Issues in Pregnancy
- Cancer, Lipids, and Metabolism
- Aortic Disease and Treatment Approaches
- Acute Ischemic Stroke Management
- Eosinophilic Esophagitis
Nuffield Health
2018-2024
National Health and Medical Research Council
2024
University of Oxford
2012-2022
Thrombolytic therapy with intravenous alteplase within 4.5 hours of ischemic stroke onset increases the overall likelihood an excellent outcome (no, or nondisabling, symptoms). Any improvement in functional distribution has value, and herein we provide assessment effect on level by treatment delay, age, severity.
Previous meta-analyses of summary data from randomised controlled trials have shown that statin therapy increases the risk diabetes, but less is known about size or timing this effect, who at greatest risk. We aimed to address these gaps in knowledge through analysis individual participant large, long-term, randomised, double-blind therapy.