A5018508891- Cancer-related Molecular Pathways
- Thyroid Cancer Diagnosis and Treatment
- Cancer Cells and Metastasis
- MicroRNA in disease regulation
- Cancer, Hypoxia, and Metabolism
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Histone Deacetylase Inhibitors Research
- Salivary Gland Tumors Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Metabolism, Diabetes, and Cancer
- Pancreatic function and diabetes
- RNA Interference and Gene Delivery
- Ubiquitin and proteasome pathways
- Epigenetics and DNA Methylation
- Thyroid and Parathyroid Surgery
- Circular RNAs in diseases
- Mitochondrial Function and Pathology
- Facial Nerve Paralysis Treatment and Research
- Cell death mechanisms and regulation
- Cancer Genomics and Diagnostics
- Wnt/β-catenin signaling in development and cancer
- Pituitary Gland Disorders and Treatments
- Cancer-related molecular mechanisms research
- Meningioma and schwannoma management
Air Force Medical University
2016-2025
A common digestive system cancer with a dismal prognosis and high death rate globally is breast (BRCA). BRCA recurrence, metastasis, medication resistance are all significantly impacted by stem cells (CSCs). However, the relationship between CSCs tumor microenvironment in individuals remains unknown, this information critically needed. Our research utilized bioinformatics techniques TCGA data to explore complex development. We identified 26 cell gene sets from Stem Checker database...
Colorectal cancer (CRC) is one of the most frequently occurring primary malignant tumors worldwide. Chemotherapeutic resistance a major clinical problem in treatment CRC. Therefore, it great importance to investigate novel biomarkers that may predict chemoresistance and facilitate development individualized for patients with The present study reported let-7f-5p expression was elevated chemotherapy-resistant CRC tissues compared chemotherapy-sensitive tissues. Furthermore, upregulating...
Ubiquitin-specific protease 22 (USP22) aberrance has been implicated in several malignancies; however, whether USP22 plays a role anaplastic thyroid carcinoma (ATC) remains unclear. Here, we report that expression is highly elevated ATC tissues, which positively correlated with tumor size, extracapsular invasion, clinical stages, and poor prognosis of patients. In vitro assays showed depletion suppressed cell survival proliferation by decreasing Rb phosphorylation cyclin D2, inactivating...
Human MARCH5 is a mitochondrial localized E3 ubiquitin-protein ligase that critical for the regulation of dynamics. A body evidence has indicated close links between unbalanced dynamics and cancers. However, expression, biological functions, prognostic significance in breast cancer (BC) have not been determined.The mRNA protein expressions were evaluated by quantitative real-time PCR Western blot analysis BC cell lines tumor tissues. Clinical was assessed 65 patients with BC. The functions...
Tumor cells use aerobic glycolysis to rapidly generate ATP and growth substrate which expenses a large amount of glucose. However, how tumor take in enough glucose from the microenvironment insufficient blood supply remains poorly understood. The cellular FLICE-like inhibitory protein (FLIP), cell apoptosis inhibiting molecule, is highly expressed hepatocellular carcinoma (HCC) implicated HCC development.The effects FLIPL (the long form FLIP) on uptake were assessed xenograft tumors....
Background: This study aimed to evaluate the feasibility and safety of three-dimensional (3D) high-definition (HD) laparoscope via a chest-breast approach in thyroid microcarcinoma.
Objective : The parotid gland is closely related to the facial nerve. Appropriate nerve dissection helpful protect function. purpose of this study evaluate and its adjacent structures by preoperative CT, so as guide during surgery. Method A total 45 patients with benign tumor diagnosed pathology were collected. According two methods was used. Twenty-one in group dissected anterograde method from trunk Other 24 Group B retrograde through branch occurrence function injury recovery time...