Our previous works have demonstrated that Chinese herb medicine yanhusuo (Corydalis W. T. Wang) has strong anti-cancer proliferation effect in MDA-MB-231 cells. The goal of this study was to find out the synergic cytotoxicity three natural compounds, tetrahydropalmatine (THP), berberine (Ber), and dehydrocorydaline (DHC), isolated from C. Wang.The IC50 THP Ber DHC single use, as well combination use at fixed ratios doses measured by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium...

Fetuin-A was considered to be involved in pathogenesis of type 2 diabetes. On the other hand, higher vascular endothelial growth factor (VEGF) expression is associated with diabetes and its complications, but mechanisms leading VEGF levels are still not clear. To best our knowledge, there no data show associations between fetuin-A patients Therefore, aim this study investigate relationship serum concentrations We recruited 345 newly diagnosed Serum were measured using enzyme-linked...

Puerarin is the main biologically active isoflavone in Pueraria lobata and has a wide range of biological activities. However, due to its poor water solubility low oral bioavailability, clinical applications are restricted. Compared with puerarin, extract (PLE) better solubility, lower toxicity, less side effects. In this study, pharmacokinetics orally administered puerarin (100 mg/kg) PLE (763 mg/kg, equivalent 100.0 mg/kg puerarin) rats was investigated by UHPLC-MS/MS method. Results...

An approach of power spectrum estimation is utilized to extract the feature vectors from acoustic signal radiated different types moving vehicles. A method selection based on principal component analysis (PCA) proposed reconstruct effective via dimension reduction. The classification three typical targets achieved by supported vector machine (SVM). Experiment results show that presented in paper for automatic recognition vehicle type effective.

The structure of traditional distribution network is changed from a single supply radial to more power ring when grid connected with distributed generations (DG), and island phenomenon occurs higher in the process reconstruction, which becomes uncontrolled high risk operation increased difficulty reconstruction. improved immune genetic algorithm introduced principle biological mechanism into standard put forward, problem premature convergence calculation overcome, constraint conditions...

Objective. The study aimed to explore the efficacy of pulmonary surfactant (PS) combined with Mucosolvan in diagnosis meconium aspiration syndrome (MAS) newborns through ultrasonic images lung based on machine learning. Methods. 138 cases infants MAS were selected as research subjects and randomly divided into PS group (n = 46), combination 46). Then, learning algorithm used for examination. On basis conventional treatment, accepted intratracheal drip treatment 100 mg/kg. For group, 7.5...

To investigate the correlation between echocardiographic indicators and expression level of N-terminal pro-brain natriuretic peptide (NT-proBNP) in premature infants (PIs) with patent ductus arteriosus (PDA) value NT-proBNP diagnosing symptomatic PDA (sPDA) PIs whose gestational age (GA) was less than 32 weeks.Ninty were selected as research objects, including 52 non-PDA group 38 (26 sPDA cases 12 asymptomatic (asPDA)) from February 2019 to March 2020. The general information these recorded,...

The association between serum fetuin A and diabetic nephropathy (DN) in patients with type 2 diabetes mellitus(T2DM) was investigated.Serum levels of fetuin-A adiponectin were measured by ELISA the clinical data collected 101 T2DM normal albuminuria (NA group),87 microalbuminuria (MA group),44 overt (OA group),and 130 control subjects (NC group).Fetuin-A increased progressively from NC,NA,MA,to OA groups,and there significant differences among groups(P＜0.05 or P＜0.01).Fetuin-A level...

Objective. It is to study the application of edge correction algorithm (ECA) in computed tomography (CT) medical image segmentation, explore its guiding significance analysis clinical characteristics children with refractory mycoplasma pneumoniae (RMPP), and discuss therapeutic value fiberoptic bronchoscopy bronchoalveolar lavage (BAL) for RMPP. Methods. The accuracy ECA CT segmentation RMPP was compared that watershed (WSA) swarm intelligence optimization (SIOA). imaging 80 admitted...

To explore the diagnostic effect of ultrasound imaging on illness severity, and to analyze neurobehavioral development neonates with Infectious Pneumonia (IPN), Self- Adaptation (SD), Spatial Smoothing (SS) technologies were adopted build SDSS. Then, WFFSF algorithm based Wiener Filtering (WF) Feature Space Fusion (FSF) SNRP-FSF Signal-to-noise ratio post-filtering (SNRP) FSF introduced for comparison.One hundred thirty-two divided into group without respiratory failure (S1) (S2). The study...

This article is based on deep learning algorithms and uses MRI to study the development of congenital heart septal defects in neonatal brain tissue.From January 2018 December 2019, 150 cases cardiac paper defect were retrospectively analyzed 50 normal newborns neonates. The four index parametersbrain MR imaging, lateral ventricle pre-angle measurement (F/F'), body (D/ D'), caudal nucleus (C/C') analyzed. independent sample t test performed compare difference parameters between groups.F...

Objective: Use of optimal Atlas segmentation algorithm to study the imaging signs mycoplasma pneumonia with multi-slice spiral CT (HRCT), and explore value HRCT in diagnosis efficacy evaluation children.
 Methods: The retrospectively analyzed 72 patients diagnosed our hospital from January 2017 2019. data clinical were collected. was used analyze characteristics examination, curative effect summarized.
 Results: Among all patients, 37 cases unilateral lesions, 35 bilateral 19 left...

The traditional energy storage coordination optimization algorithm has long response time, low computational efficiency and high running cost, so for distributed power distribution network operation planning based on particle swarm is proposed. In order to minimize the loss of maximum deviation node voltage, model capacity configuration with system as objective function established. improved adaptive weighting method used transform target problem into single problem, which solved by (PSO)...

Objectives: The paper uses block matching method combined with echocardiography to explore the value of N-terminal pro-brain natriuretic peptide (NT-proBNP) in predicting symptomatic patent ductus arteriosus (PDA) preterm infants.
 Methods: We selected premature infants born between February 2019 and March 2020, gestational age ≤32 weeks, within 48 hours determine presence arterial ducts as research object, monitor their clinical manifestations, detect serum at three five days after...

Objective: Preterm neonates are susceptible to neonatal respiratory distress syndrome (NRDS). Lower levels of cord blood vascular endothelial growth factor (VEGF) implicated in NRDS. This study aims explore whether the serum VEGF level has prognostic values on with (RDS). Methods: A total 80 infants diagnosed NRDS were enrolled, 70 preterm without as controls. Cord samples before treatment and venous after collected clinical information was recorded. The measured using enzyme-linked...

Objective To estimate the diagnostic value of combined detection TPS, CEA,NSE,CYFRA21 - 1 in patients with lung cancer. Methods The content serum CEA, NSE, CY-FRA21 -1 and TPS were detected ECLIA. There three groups: eighty- pathologically confirmed cases cancer group, 41 benign pulmonary disease group 30 normal volunteers healthy group. Results levels CYFRA21 significantly higher than that a statistically significant decrease ( P < 0. 05 or 0.01 ). sensitivity to was 84. 34%, 51.81%,43.37%...

Schisandra Chinensis is a traditional Chinese medicine. The effects of dried schisandra impact the medicinal value and economic benefit directly. Presently, studies on characteristics uses chinensis are reported frequently in China. However, factors influencing drying effect schisanda have not been reported. In this paper, linear regression equation dry bulb temperature (Tdb) wet (Twb) process were obtained by means data connection, correlation analysis, analysis. A mathematical model Tdb...

Abstract Background Sheng-Ma-Ge-Gen-Tang (SMGGT; 升麻葛根汤) is a famous prescription of traditional Chinese medicine used against measles children for many hundreds years. And its anti-hepatitis B virus (HBV) activity has been justified in clinical, however, the function substances and mechanisms have not studied yet. Methods The latent active compounds Cimicifugae Rhizoma (Shengma)-Radix Puerariae (Gegen) drug pair were searched, excavated their related targets. Then seek targets HBV through...

This study aimed to explore the diagnostic value of chest computed tomography (CT) based on adaptive statistical iterative reconstruction (ASiR) in optimal weight range for children with community-acquired pneumonia (CAP) and find differences between CT ultrasound diagnosis CAP. 106 who were diagnosed as CAP selected research objects. All objects underwent scans measure noise images after contrast-to-noise ratio (CNR) thoracic aorta back muscles. The correlation ASiR weight, noise, CNR was...