A5103026307- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Streptococcal Infections and Treatments
- Glaucoma and retinal disorders
- Ocular Infections and Treatments
- Synthesis and biological activity
- Corneal Surgery and Treatments
- Intraocular Surgery and Lenses
- Microbial Natural Products and Biosynthesis
- Synthesis and Biological Evaluation
- Microbial infections and disease research
- Toxin Mechanisms and Immunotoxins
- Antimicrobial Resistance in Staphylococcus
- Traumatic Ocular and Foreign Body Injuries
- Neonatal and Maternal Infections
- Ocular Surface and Contact Lens
- Chronic Kidney Disease and Diabetes
- Cancer therapeutics and mechanisms
- Acute Kidney Injury Research
- Marine Sponges and Natural Products
- Congenital Heart Disease Studies
- Antibiotics Pharmacokinetics and Efficacy
- Congenital heart defects research
- Dialysis and Renal Disease Management
- Inflammasome and immune disorders
Hubei Academy of Agricultural Sciences
2014-2025
Sun Yat-sen University
2015-2024
Cornell University
2024
China Automotive Technology and Research Center
2022-2024
Sichuan University
2020-2024
First Affiliated Hospital of Jinan University
2020-2024
State Key Laboratory of Oral Diseases
2023-2024
Ministry of Agriculture and Rural Affairs
2022-2024
Guizhou Provincial People's Hospital
2022-2023
University of California, San Francisco
2023
To compare the clinical outcomes of small-incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK (FS-LASIK) for correction myopia myopic astigmatism.In this prospective, randomized, comparative study, SMILE surgery was performed in 113 eyes with a mean spherical equivalent (MSE) -5.22 ± 1.70 diopters (D) FS-LASIK 84 an MSE -5.18 1.93 D. Contrast sensitivity uncorrected corrected distance visual acuities were measured preoperatively 1 day, week, 1, 3, 6 months...
To compare the corneal biomechanical properties before and after small incision lenticule extraction (SMILE) femtosecond laser-assisted LASIK in different levels of myopia with Ocular Response Analyzer (Reichert Ophthalmic Instruments, Depew, NY).A total 187 79 eyes that received SMILE or LASIK, respectively, between January June 2013 at Zhongshan Center were enrolled this study. Patients grouped according to surgery type (SMILE LASIK) -6.00 diopters (D) less (> D) greater than D (>-6.00 D)....
The current study aimed to examine the short-term choroidal response optical defocus in schoolchildren. Myopic schoolchildren aged 8–16 were randomly allocated control group (CG), myopic (MDG) and hyperopic (HDG) (n = 17 per group). Children MDG HDG received additional +3D -3D lenses, respectively, their full corrections on right eyes. Full correction was given left eyes, both eyes CG. Axial length (AXL) subfoveal thickness (SFChT) then measured by spectral domain coherence tomography. wore...
Chemical investigation of the mangrove sediment-derived fungus Striaticonidium cinctum SCSIO 41432 resulted in isolation 27 new benzofuran polyketides, including diverse monomeric (1−21), dimeric (22 and 23), trimeric (24),...
To evaluate decentration from pupil center and corneal vertex normal following femtosecond laser small incision lenticule extraction (SMILE) for the treatment of myopia myopic astigmatism.This study evaluated 101 eyes patients with a spherical equivalent (SE) -5.30 ± 1.72 diopters (D). Decentration was measured in pupil-centered group (PC group) by video capture images normal-centered (VNC using WaveLight Oculyzer II (Alcon). The PC VNC groups were further divided into 4 subgroups (1 PC, 2 1...
To discover bioactive natural products from mangrove sediment-derived microbes, a chemical investigation of the two Beibu Gulf-derived fungi strains, Talaromyces sp. SCSIO 41050 and Penicillium 41411, led to isolation 23 products. Five them were identified as new ones, including polyketide derivatives with unusual acid anhydride moieties named cordyanhydride A ethyl ester (1) maleicanhydridane (4), three hydroxyphenylacetic stachylines H-J (10-12). Their structures determined by detailed...
Three new naphthoquinone-based meroterpenoids (1–3), including spironaphthomeroterpenoid (1), a novel meroterpenoid with rare [5, 6] spiro-ring skeleton, and naphthablins D E (2–3), along three known analogues (4–6) were isolated from Streptomyces sp. HBERC-16614. The structures of these compounds, their absolute configurations, established by extensive spectroscopic analysis electronic circular dichroism (ECD) spectrum. antibacterial activities compounds (1–6) evaluated against...
Porcine extra-intestinal pathogenic Escherichia coli (ExPEC) causes great economic losses to the pig industry and poses a serious threat public health worldwide. Some secreted virulence factors have been reported be involved in pathogenicity of infection caused by ExPEC. Type-VI secretion system (T6SS) is discovered many Gram-negative bacteria contributes bacteria. Valine-glycine repeat protein G (VgrG) has as an important component functional T6SS. In our previous studies, T6SS was...
To evaluate the clinical results of suction loss in eyes during small incision lenticule extraction (SMILE).This prospective paired-eye case study enrolled 8,490 4,296 patients, which 35 experienced SMILE procedure while being treated for myopia or myopic astigmatism. The with were re-treated SMILE, femtosecond laser-assisted LASIK (FS-LASIK), pseudo and fellow SMILE. Patients examined before surgery at 1 day, week, 3 months postoperatively. Corrected distance visual acuity (CDVA)...
Streptococcus suis serotype 2 is a serious zoonotic pathogen and has attracted worldwide attention since the first human case was reported in Denmark 1968. Some virulence factors have been to be involved pathogenesis of infection caused by 2, then novel strategies identify some anti-virulence compounds which can effectively inhibit pathogenic bacterial recently reported. Suilysin an essential factor for it creates pores target cells membranes, aids colonization. The important role suilysin...
Streptococcus suis serotype 2 (S. 2) is an important pathogen of pigs. S infections have high mortality rates and are characterized by meningitis, septicemia pneumonia. S. also emerging zoonotic agent can infect humans that exposed to pigs or their by-products. To increase our knowledge the pathogenesis pneumonia in caused 2, we profiled response peripheral blood mononuclear cells (PBMC), brain lung tissues infection with strain SC19 using Affymetrix Porcine Genome Array.A total 3,002...
To evaluate clinical outcomes after small incision lenticule extraction (SMILE) with different cap thicknesses in thick corneas.Forty patients central corneal thickness of more than 560 μm were recruited this prospective, randomized, masked, paired-eye study. Patients randomized to receive SMILE a 120-μm 1 eye and 140-μm the other. Uncorrected corrected distance visual acuity (CDVA), contrast sensitivity (CS), higher-order aberrations (HOAs), morphologic modifications architecture measured...