A5100433321- Autism Spectrum Disorder Research
- Nanoplatforms for cancer theranostics
- Luminescence Properties of Advanced Materials
- Vibrio bacteria research studies
- Luminescence and Fluorescent Materials
- RNA modifications and cancer
- Genetics and Neurodevelopmental Disorders
- Epigenetics and DNA Methylation
- Escherichia coli research studies
- Lipid metabolism and biosynthesis
- Cancer-related molecular mechanisms research
- Salmonella and Campylobacter epidemiology
- Nitrogen and Sulfur Effects on Brassica
- Ferroptosis and cancer prognosis
- Nanoparticle-Based Drug Delivery
- Advanced Chemical Sensor Technologies
- Cancer-related gene regulation
- Graphene and Nanomaterials Applications
- Peroxisome Proliferator-Activated Receptors
- Nutrition, Genetics, and Disease
- Circular RNAs in diseases
- Congenital heart defects research
- Augmented Reality Applications
- Marine Sponges and Natural Products
- Pediatric health and respiratory diseases
First Affiliated Hospital Zhejiang University
2024
Zhejiang Lab
2024
Zhejiang University
2024
Jilin University
2008-2024
First Hospital of Jilin University
2008-2024
Huazhong Agricultural University
2021-2022
Tongji Hospital
2022
Huazhong University of Science and Technology
2022
Center of Hubei Cooperative Innovation for Emissions Trading System
2021
Harbin Medical University
2018-2019
To explore the geographical pattern and temporal trend of autism spectrum disorders (ASD) epidemiology from 1990 to 2019, perform a bibliometric analysis risk factors for ASD.In this study, ASD was estimated with prevalence, incidence, disability-adjusted life-years (DALYs) 204 countries territories by sex, location, sociodemographic index (SDI). Age-standardized rate (ASR) annual percentage change (EAPC) were used quantify trends. Besides, study performed since 1990. Publications published...
Synergistic photodynamic therapy (PDT) with other therapeutic modalities can enhance the efficacy of tumor treatment and reduce adverse effects associated drug leakage off-target accumulation.
Bone donor site infection (BDSI) is a main complication of bone harvest in spine surgery. Traditionally, repeated wound dressing changes (RWDC) after debridement are commonly used to treat BDSI but associated with significant pain and largely prolonged hospitalization. This study retrospectively compared the effectiveness closed irrigation drainage (CIAD) RWDC treating BDSI. A total 21 cases secondary different spinal procedures period 15 years were included. Twelve treated by earlier...
Abstract Background The upgrading of rapeseed cultivars has resulted in a substantial improvement yield and quality China over the past 30 years. With selective pressure against fatty acid composition oil content, high erucic acid- low oil-content have been replaced by cultivars. cultivar Zhongyou 821 its descendent, Zhongshuang 9, are representatives two generations most outstanding Chinese ( B. napus ) developed 2 decades. This paper compares transcriptional profiles 9 for 32 genes that...
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Aberrant DNA methylation has been observed in ASD but the mechanisms remain largely unknown. Here, we employed discordant monozygotic twins to investigate contribution of etiology. Genome-wide analysis was performed using samples obtained from five pairs ASD-discordant twins, which revealed total 2,397 differentially methylated genes. Further, such gene list annotated with Kyoto Encyclopedia Genes and Genomes...
Introduction . Lung adenocarcinoma (LAC) is the most frequent type of lung cancer and has a high metastatic rate at an early stage. This study aimed identifying LAC-associated genes. Materials Methods GSE62950 downloaded from Gene Expression Omnibus included DNA methylation dataset mRNA expression profiles dataset, both which 28 LAC tissue samples adjacent normal samples. The differentially expressed genes (DEGs) were screened by Limma package in R, their functions predicted enrichment...
Protein-based drugs offer advantages, such as high specificity, low toxicity, and minimal side effects compared to small molecule drugs. However, delivery of proteins target tissues or cells remains challenging due the instability, diverse structures, charges, molecular weights proteins. Polymers have emerged a leading choice for designing effective protein systems, but identifying suitable polymer given is complicated by complexity both polymers. To address this challenge,...
Autism spectrum disorder (ASD) is a set of complex neurodevelopmental disorders with etiology remains elusive. Although there mounting body investigation in different brain regions related to ASD, our knowledge about the common and distinct perturb condition between them at threshold accumulation. In this study, based on protein-protein interactions, post-mortem transcriptome analysis was performed corpus callosum (CC) prefrontal cortex (PFC) samples from ASD individuals controls....
Cholesterol is a vital compound in maintenance for human health, and its concentration levels are tightly associated with various diseases. Therefore, accurate monitoring of cholesterol great significance clinical diagnosis. Herein, we fabricated noncontact biosensor based on photonic crystal-enhanced upconversion nanoparticles (UCNPs) highly sensitive interference-free detection. By compounding LiErF4:0.5%Tm3+@LiYF4 UCNPs poly(methyl methacrylate) (PMMA) crystals (OPCs), were able to...
Autism spectrum disorder (ASD) presents a set of childhood neurodevelopmental disorders with impairments in social communication and restricted, repetitive, stereotyped patterns behavior. Here, based on the whole-genome sequencing (WGS) data three monozygotic twins discordant for ASD, we explored multiple patient-specific genetic variations prioritized list ASD risk genes. Our results identified DVMT (discordant variation twin) observed at least two twin pairs, including 14,310 SNPs, 2,425...
Pharmacognosy Magazine ,2019,15,61,283-289.DOI:10.4103/pm.pm_365_18Published:March 2019Type:Original Article Authors:Qingfeng He, Yunjing Luo, Pingping Zhang, Chengsong An, Ailin Xiaodan Li, Lingling You, and Cuicui Liu Author(s) affiliations:Qingfeng He1, Luo2, Zhang3, An3, Li3, You3, Liu3 1College of Life Science Bioengineering, Beijing University Technology, Chaoyang, Beijing; Department Food Quality Safety, College Biotechnology, Tianjin Agricultural University, Xiqing, Tianjin, China...
Abstract Fluorescence/luminescence bioimaging, utilizing rare‐earth doped nanocrystals (RENCs) within the NIR‐IIb (1500–1700 nm) sub‐window, has drawn interest for its deep penetration depth and superior resolution. Herein, Er 3+ /Yb couple is rationally designed in topologically arranged RENCs that facilitate a boosted 1530 nm emission of via premeditated Yb ‐mediated energy transfer processes under 808 excitation. To maximize this modulation effect boosting emission, regional active ions...
Acute respiratory distress syndrome (ARDS) remains a severe disease associated with an ~40% mortality rate and as many 200,000 new cases annually. MicroRNAs (miRNAs) have important roles in gene regulation cancer development. The present study aimed to identify the potential of miRNAs pathogenesis progression ARDS. miRNA expression profile GSE57223 dataset was downloaded from Gene Expression Omnibus database. Following data normalization, differentially expressed were identified using t‑test...
Autism spectrum disorder (ASD) is a complex neurodevelopmental disease in early childhood, and growing up to be major cause of disability children.However, the underlying molecular mechanism ASD remains elusive.Hence, we represented integrated multifactor analysis exploring dysfunctional modules based on RNA-Seq data from corpus callosum 6 patients with normal individuals.According protein-protein interactions (PPIs) WGCNA, performed co-expression for ASD-associated genes, identified 25...
We evaluated the key genes related with recurrent respiratory tract infections (RRTIs), and then elucidated possible molecular mechanisms of RRTIs. Neutrophil was isolated from peripheral bloods lower infection patients healthy volunteers, respectively. The next generation sequencing information obtained after RNA extraction, purification, library construction sequencing. preprocessed. Bioinformatics analysis including differentially expre-ssed (DEGs), Gene Ontology (GO) pathway enrichment...