A5059170890- COVID-19 Clinical Research Studies
- Antibiotic Resistance in Bacteria
- Enterobacteriaceae and Cronobacter Research
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
- Neonatal and Maternal Infections
- Probiotics and Fermented Foods
- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- Infective Endocarditis Diagnosis and Management
- Streptococcal Infections and Treatments
- Pharmaceutical and Antibiotic Environmental Impacts
- COVID-19 Pandemic Impacts
- Gut microbiota and health
National and Kapodistrian University of Athens
2020-2024
Abstract Background There is limited information on the association between upper respiratory tract (URT) viral loads, host factors, and disease severity in SARS-CoV-2–infected patients. Methods We studied 1122 patients (mean age, 46 years) diagnosed by polymerase chain reaction (PCR). URT load, measured PCR cycle threshold, was categorized as high, moderate, or low. Results were 336 (29.9%) with comorbidities; 309 (27.5%) had 316 (28.2%) 497 (44.3%) low load. In univariate analyses,...
There is limited information on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection clustering within families with children. We aimed to study the transmission dynamics of SARS-CoV-2 children in Greece. studied 23 family clusters disease 2019 (COVID-19). Infection was diagnosed by reverse-transcriptase polymerase chain reaction specimens. The level viral load categorized as high, moderate, or low based cycle threshold values. were 109 household members (66 adults and 43...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel responsible for the disease 2019 (COVID-19) pandemic. Chains of infections starting from various countries worldwide seeded outbreak COVID-19 in Athens, capital city Greece. A full-genome analysis isolates Athens' hospitals and other healthcare providers revealed variety SARS-CoV-2 that initiated pandemic before lockdown passenger flight restrictions. dominant variant, encompassing G614D amino acid substitution, spread...
Objectives: Streptococcus pyogenes causes superficial infections, but can also cause deep-seated infections and toxin-mediated diseases. In the present study, phylogenetic in silico prediction analyses were performed on an antimicrobial-resistant M1UK S. strain causing severe clinical manifestations during current surge of invasive group A (iGAS) disease. Patient Methods: 40-year-old patient was admitted to hospital with fever, chest pain, fatigue. Based laboratory findings a diagnosis...
Background: Carbapenemase-producing Enterobacter cloacae complex (ECC) are increasingly identified in hospital-acquired infections. They usually belong to four main multilocus sequence types (STs) named ST114, ST93, ST90, and ST78. Instead, ST182 has been sporadically reported, recently outbreaks of blaNDM-producing strains have emerged. Herein, we aimed investigate the presence explore its evolution modes blaNDM acquisition. Methods: A phylogenetic analysis 646 MLST STs among 4,685 E....
Nosocomial outbreaks of multidrug-resistant (MDR) Enterobacter cloacae complex (ECC) are often reported worldwide, mostly associated with a small number multilocus-sequence types E. hormaechei and strains. In Europe, the largest clonal outbreak blaNDM-1-producing ECC has been recently reported, involving an ST182 strain in Greek teaching hospital. current study, we aimed to further investigate genetic make-up two representative isolates. Comparative genomics whole genome sequences (WGS) was...
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