Chun Li

ORCID: 0000-0003-1851-3691
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About
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Research Areas
  • Genetic diversity and population structure
  • Plant Molecular Biology Research
  • Plant Virus Research Studies
  • Plant Stress Responses and Tolerance
  • Plant and Fungal Species Descriptions
  • Genetic and phenotypic traits in livestock
  • Photosynthetic Processes and Mechanisms
  • Plant-Microbe Interactions and Immunity
  • Meat and Animal Product Quality
  • Healthcare Education and Workforce Issues
  • Genomics and Chromatin Dynamics
  • Gene expression and cancer classification
  • Microbial Metabolic Engineering and Bioproduction
  • Autophagy in Disease and Therapy
  • Plant-based Medicinal Research
  • Wildlife Ecology and Conservation
  • Animal Vocal Communication and Behavior
  • Plant Disease Resistance and Genetics
  • Plant responses to elevated CO2
  • Legume Nitrogen Fixing Symbiosis
  • Plant tissue culture and regeneration
  • Plant Gene Expression Analysis
  • Infectious Diseases and Tuberculosis
  • Optimism, Hope, and Well-being
  • Palliative and Oncologic Care

The University of Texas MD Anderson Cancer Center
2015-2025

Sichuan Academy of Agricultural Sciences
2023-2024

Science and Technology Department of Sichuan Province
2023

Xinjiang Production and Construction Corps
2011-2022

University of Science and Technology Beijing
2006-2022

Beijing Institute of Technology
2011-2022

Shihezi University
2011-2022

Tsinghua University
2022

Ministry of Industry and Information Technology
2022

China Medical University
2021

Abstract Background Climate change has led to severe cold events, adversely impacting global crop production. Eggplant ( Solanum melongena L. ), a significant economic crop, is highly susceptible damage, affecting both yield and quality. Unraveling the molecular mechanisms governing resistance, including identification of key genes comprehensive transcriptional regulatory pathways, crucial for developing new varieties with enhanced tolerance. Results In this study, we conducted comparative...

10.1186/s12870-024-04922-y article EN cc-by BMC Plant Biology 2024-04-09

Abstract Introduction: EphB4 is frequently overexpressed in ovarian and other solid tumors involved interactions between tumor cells microenvironment, contributing to metastasis. its membrane-bound ligand ephrin B2 (EFNB2) mediates bi-directional signaling. Currently, no small-molecule-based, peptides with dual functional binding are available. Therefore, we developed an agonist that capable of activating the forward signaling interfering reverse EFNB2 Methods: A high-affinity peptide...

10.1158/1538-7445.am2020-122 article EN Cancer Research 2020-08-15

Curcuma longa (turmeric) is a folk medicine in South and Southeast Asia, which has been widely used to alleviate chronic inflammation. Aromatic-turmerone one of the main components abundant turmeric essential oil. However, little information available from controlled studies regarding its biological activities underlying molecular mechanisms against inflammation brain. In current study, we employed classical LPS model study effect mechanism aromatic-turmerone on neuroinflammation.The effects...

10.1002/mnfr.201700281 article EN Molecular Nutrition & Food Research 2017-08-29

Introduction: Pancreatic ductal adenocarcinoma (PDAC) and hepatocellular carcinoma (HCC) remain the leading causes of cancer-related mortality, with poor outcomes. This study comprehensively evaluated mechanisms polymeric micelles co-encapsulating cyclopamine (CPA) paclitaxel (PTX) (M-CPA/PTX, ONP-001) effectiveness against HCC PDAC. The dual-drug delivery system targets embryonic signaling pathways, such as Hedgehog (Hh), which drives tumor progression resistance. Methods: CPA PTX were...

10.1158/1538-7445.am2025-3141 article EN Cancer Research 2025-04-21

Calmodulin-binding transcription activator (CAMTA) is an important calmodulin-binding protein with a conserved structure in eukaryotes which widely involved plant stress response, growth and development, hormone signal transduction, other biological processes. Although CAMTA genes have been identified characterized many species, systematic comprehensive analysis of the Solanaceae genome performed for first time this study. A total 28 were using bioinformatics tools,...

10.3390/ijms25042064 article EN International Journal of Molecular Sciences 2024-02-08

Inflammation is a common inducer of numerous severe diseases such as sepsis. The NF-κB signaling pathway plays key role in the inflammatory process. Its activation promotes release pro-inflammatory mediators like inducible nitric oxide synthase and tumor necrosis factor alpha. Peroxisome proliferator-activated receptor gamma (PPAR-γ) inactivates nuclear kappa B (NF-κB) subsequently attenuates inflammation. Rhein, an agent isolated from rhubarb, has been known to have anti-inflammatory...

10.1139/cjpp-2019-0389 article EN Canadian Journal of Physiology and Pharmacology 2019-12-17

Abstract Stroke remains one of the leading causes permanent disability and death worldwide. Apoptosis autophagy are two key elements involved in ischemic brain damage. Ethanol is a commonly used abused chemical substance that affects prognosis stroke. We determined influence chronic ethanol consumption on apoptosis following transient focal cerebral ischemia. Male C57BL/6 J mice were randomly divided into three groups gavage fed with 0.7 2.8 g/kg/day or volume-matched water daily for 8...

10.1038/s41598-020-63213-2 article EN cc-by Scientific Reports 2020-04-09

This study aimed at evaluating the ability of SL-44 to control Rhizoctonia solani and promote pepper (Capsicum annuum) growth. Strain was isolated from plant rhizosphere pot experiment results indicated that dry fresh weights in (S-R) treatment were 45.5% 54.2% higher than those (R) 18.2% 31.8% CK (control, noninoculation) treatment. The height S-R increased by 14.2% 9.0% compared with R treatments, respectively. In vitro antagonism assay showed exhibited strong antifungal activity against...

10.1155/2017/9397619 article EN cc-by BioMed Research International 2017-01-01

10.1016/j.physa.2017.05.032 article EN Physica A Statistical Mechanics and its Applications 2017-05-31

10.1007/s13562-023-00862-0 article EN Journal of Plant Biochemistry and Biotechnology 2023-12-01

In gene expression data analysis, clustering is a fruitful exploratory technique to reveal the underlying molecular mechanism by identifying groups of co-expressed genes. To reduce noise, usually multiple experimental replicates are performed. An integrative analysis full replicate data, instead reducing mean profile, carries promise yielding more precise and robust clusters. this paper, we propose novel resampling based algorithm for genes with replicated measurements. Assuming those...

10.1109/tcbb.2015.2403320 article EN IEEE/ACM Transactions on Computational Biology and Bioinformatics 2015-02-13

Cyamodontoidea is an armoured lineage of Placodontia, the basal-most clade Sauropterygia. It was unknown in China until Sinocyamodus xinpuensis reported 2000, on basis a subadult specimen. Here we describe first adult specimen this taxon. This nearly complete determined to be S. by stout triangular skull with short snout, nasal–nasal contact, carapace three types osteoderms developing rows meridional ridges and vaulted zones both sides phalangeal formula 2-3-4-4-2. In study, diagnosis...

10.1093/zoolinnean/zly080 article EN Zoological Journal of the Linnean Society 2018-10-14

A novel Gram-stain-negative strain, WQ 117T, isolated from the faeces of Rhinopithecus bieti collected at Yunnan Snub-nosed Monkey National Park, province, PR China, was subjected to a polyphasic taxonomic study. The results phylogenetic analysis based on 16S rRNA gene sequences indicated that isolate represented member genus Faecalibacter, sharing 97.64 % sequence similarity with type strain Faecalibacter macacae YIM 102668T. G+C content genomic DNA WQ117T 30.5 mol%. predominant isoprenoid...

10.1099/ijsem.0.004932 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2021-08-12
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