- Parasites and Host Interactions
- Coastal and Marine Dynamics
- Research on Leishmaniasis Studies
- Geophysics and Gravity Measurements
- Tropical and Extratropical Cyclones Research
- Liver Disease and Transplantation
- Parasite Biology and Host Interactions
- HIV/AIDS Research and Interventions
- Flood Risk Assessment and Management
- Trypanosoma species research and implications
- Leprosy Research and Treatment
- Coastal wetland ecosystem dynamics
- Parasitic Diseases Research and Treatment
- Remote Sensing and LiDAR Applications
- 3D Surveying and Cultural Heritage
- Geology and Paleoclimatology Research
- SARS-CoV-2 and COVID-19 Research
- Child Nutrition and Water Access
- Iron Metabolism and Disorders
- Mosquito-borne diseases and control
- earthquake and tectonic studies
- HIV-related health complications and treatments
- Amoebic Infections and Treatments
- Geological and Geophysical Studies Worldwide
- Nutrition and Health in Aging
University of Lisbon
2012-2025
Instituto Dom Luiz
2023-2025
IdMind (Portugal)
2012-2024
Fundação Oswaldo Cruz
2016-2024
Eindhoven University of Technology
2022
Instituto de Ensino e Pesquisa Santa Casa
2011-2020
Grupo Santa Casa de Belo Horizonte
2006-2014
Universidade Federal de Minas Gerais
2003-2012
Universidade Federal de Ouro Preto
2011
Hospital das Clínicas da Universidade Federal de Minas Gerais
2006
Two controlled, double blind field trials of a non-living promastigote vaccine against New World Cutaneous Leishmaniasis (NWCL) were conducted in 1981 and 1983 Brazil. Brazilian Army conscripts randomly assigned to the or placebo groups tested during their training Amazon jungle, high risk area for NWCL. The results obtained showed: (1) no significant differences between with respect number characteristics (age, race, previous contact etc.); (2) participants who got did not get NWCL trial,...
Sea level rise, a consequence of climate change, is one the biggest challenges that countries and regions with coastal lowlands will face in medium term. This study proposes methodology for assessing vulnerability to sea-level rise on Atlantic coast mainland Portugal. Some scenarios extreme sea levels different return periods flooding events were estimated 2050 2100, as proposed by European Directive 2007/60/EC. A set physical parameters are considered multi-attribute analysis based Analytic...
Journal Article Failure of a killed Leishmania amazonensis vaccine against American cutaneous leishmaniasis in Colombia Get access Iván D. Vélez, Vélez * aPrograma de Estudio y Control Enfermedades Tropicales, PECET, Universidad Antioquia, Apartado Aéreo 1226, Calle 62 # 52-59 Medellín, *Corresponding author. Tel.: +57 4 210 65 01; fax: 02. E-mail address: idvelez@udea.edu.co (I.D. Vélez). Search for other works by this author on: Oxford Academic PubMed Google Scholar Katherine Gilchrist,...
Schistosomiasis mansoni is a major cause of portal fibrosis and hypertension. The Hedgehog pathway regulates fibrogenic repair in some types liver injury.Determine if activation occurs during progression schistosomiasis to determine macrophage-related mechanisms are involved.Immunohistochemistry was used characterize the cells that generate respond ligands 28 biopsies from patients with different grades staged by ultrasound. Cultured macrophages (RAW264.7 primary rat Kupffer cells)...
In the first days of 2014, exceptionally energetic swells associated to Hercules storm (also known as "Christina") produced one most devastating coastal events in Portugal, establishing new records long-term wave observations for area. Between January 6th and 7th, extreme flooding affected >30 municipalities along Portuguese coastlines, with buoys measuring maximum individual heights periods 14.91 m 28.10 s, respectively. The caused >16 million euros direct costs, due overtopping flooding,...
Some of the most disruptive effects climate change are projected to be felt along coastlines. The combined future changes in water levels and wave coastal areas constitute one serious threats their sustainable evolution, compromising critical infrastructures, resources, ecosystems, communities. Understanding long-term remains challenging, however, due multivariate multi-time-and-space-scale nature. In this study, we propose an innovative methodology for a complete vulnerability assessment...
In order to understand the determinants of human infection by Leishmania chagasi in an urban area, a cross-sectional population based study was conducted using molecular and serologic methods identify infection. Participants were interviewed pre-coded questionnaire. Two criteria tested risk factors: Model 1- including all participants positive hybridization donovani complex probe; 2- for at least one test. 1, variables associated with were: ownership birds, time spent outside house between...
Abstract. In this study, we present 10 m resolution tsunami flooding maps for Lisbon downtown and the Tagus estuary. To compute these use bathymetry topographic a reasonable estimate maximum credible scenario. Tsunami modeling was made with non-linear shallow water model using four levels of nested grids. The flood is discussed in terms flow depth, run-up height inundation area. results show that, even today, spite significant morphologic changes city river front after 1755 earthquake,...
INTRODUCTION: The Kato-Katz technique is the standard diagnostic test for Schistosoma mansoni infection in rural areas. However, utility of this method severely limited by day-to-day variability host egg excretion stool. In high-transmission areas, point-of-care circulating cathodic antigen (POC-CCA) urine assay has proven to be a reliable test. investigations reliability POC-CCA low-transmission regions are under way. This study aimed evaluate sensitivity and specificity morbidity...
Background. The best treatment for schistosomal myeloradiculopathy (SMR) remains undefined. There is also no longitudinal study to estimate the value of magnetic resonance imaging (MRI) in diagnosis and follow-up this disease.
Portugal’s mainland has hundreds of thousands people living in the Atlantic coastal zone, with numerous high economic value activities and a number infrastructures that must be adapted protected from natural hazards, namely, extreme storms sea level rise (SLR). In context climate change adaptation strategies, reliable accurate assessment physical vulnerability to SLR is crucial. This study contribution implementation flooding standards imposed by European Directive 2007/60/EC, which requires...
Some of the most disruptive effects climate change are projected to be felt along coastlines. The combined future changes in water levels and wave coastal areas constitute one serious threats their sustainable evolution, compromising critical infrastructures, resources, ecosystems, communities. Understanding long-term remains challenging, however, due multivariate multi-time-and-space-scale nature. In this study, we propose an innovative methodology for a complete vulnerability assessment...
Brazilian army conscripts were vaccinated against American cutaneous leishmaniasis by using nonliving polyvalent promastigote Leish vaccine 5 or 6 (vaccines with five six Leishmania stocks) without Corynebacterium parvum. No statistically significant differences in lymphocyte stimulation indices found between groups C. parvum, but of all vaccinees significantly higher (P less than 0.001) those the placebo group. A correlation 90% was positive skin test results and indices. Eight major...
A population-based cross-sectional study was set up in Sabará country, Southeastern Brazil, to identify asymptomatic human visceral leishmaniasis an urban area of low disease prevalence. Blood collected on filter paper (n=1,604 inhabitants) and examined by indirect immunofluorescent test, enzyme-linked immunosorbent assay immunochromatographic strip test. The prevalence rates infection ranged from 2.4 5.6% depending the test used. One year later, venous blood a subset 226 participants (102...
Based on the updated relative sea level rise rates, 21st-century projections are made for west coast of Portugal Mainland. The mean from Cascais tide gauge and North Atlantic satellite altimetry data have been analyzed. Through bootstrapping linear regression polynomial adjustments, time series were used to calculate different empirical rise, by estimating initial velocity its corresponding acceleration. results consistent with an accelerated showing evidence a faster than previous century...