A5018563600- Congenital Heart Disease Studies
- Neonatal Respiratory Health Research
- Cardiovascular Conditions and Treatments
- Infant Nutrition and Health
- Cardiovascular Issues in Pregnancy
- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Cholesterol and Lipid Metabolism
- Microscopic Colitis
- Protein Tyrosine Phosphatases
- Congenital heart defects research
- Williams Syndrome Research
- Peptidase Inhibition and Analysis
- Galectins and Cancer Biology
- Kawasaki Disease and Coronary Complications
- Congenital Diaphragmatic Hernia Studies
- Vitamin D Research Studies
- Pregnancy and Medication Impact
- Blood Coagulation and Thrombosis Mechanisms
- Congenital Anomalies and Fetal Surgery
Levine Children's Hospital
2021-2023
Boston Children's Hospital
2012-2021
Harvard University
2018-2021
Yale University
2013-2014
Yale New Haven Hospital
2012
Icahn School of Medicine at Mount Sinai
2006
We sought to describe growth in young children with congenital heart disease (CHD) over time.We performed a retrospective matched cohort study, identifying CHD large primary care network Pennsylvania, New Jersey, and Delaware matching them 10:1 control subjects. The endpoint was the difference mean World Health Organization z score for cases controls weight-for-age (WFAZ), length-for-age (LFAZ), weight-for-length (WFLZ), head circumference-for-age (HCFAZ) at traditional ages preventive...
We aimed to examine clinical features and outcomes of consecutive molecularly characterized patients with Noonan syndrome multiple lentigines hypertrophic cardiomyopathy.
Abstract Objective To describe the early hemodynamic changes after fetal aortic valvuloplasty (FAV) for evolving hypoplastic left heart syndrome due to mid‐gestational stenosis and assess whether these predict biventricular (BiV) circulation at neonatal discharge. Method We retrospectively reviewed all technically successful FAV cases resulting in live birth between 2000 2015 ( n = 93, 45% BiV discharge). Paired testing methods were used compare pre‐intervention post‐intervention measures of...
Prior studies of vitamin D metabolism in Crohn's disease (CD) did not include controls or examine changes following diagnosis. This study examined associations among 25-hydroxyvitamin [25(OH)D], 1,25-dihydroxyvitamin [1,25(OH)(2)D], and parathyroid hormone (PTH) levels incident pediatric CD, compared with controls,
To describe a group of children with co-incident pulmonary vein stenosis and Smith-Lemli-Opitz syndrome to generate hypotheses as the shared pathogenesis these disorders.Retrospective case series.Five subjects in cohort 170 were diagnosed soon after birth.All five cases within 6 weeks life, no family history either disorder. All had pathologically elevated 7-dehydrocholesterol levels two previously reported pathogenic reductase mutations. severity scores ranged from mild classical (2-7)....
Fetal aortic valvuloplasty (FAV) for severe stenosis (AS) has shown promise in averting progression to hypoplastic left heart syndrome. After FAV, predicting which fetuses will achieve a biventricular (BiV) circulation after birth remains challenging. Identifying predictors of postnatal on late gestation echocardiography improve parental counseling.Liveborn patients who underwent FAV and had available were included (2000-2017, n = 96). Multivariable logistic regression classification tree...