A5100351584- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Marine and coastal ecosystems
- Water Quality Monitoring and Analysis
- Ecology and Vegetation Dynamics Studies
- Species Distribution and Climate Change
- Pain Mechanisms and Treatments
- Microbial Community Ecology and Physiology
- Environmental Quality and Pollution
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Plant and animal studies
- Advanced Glycation End Products research
- Methane Hydrates and Related Phenomena
- Immune cells in cancer
- Evaluation Methods in Various Fields
- Pulmonary Hypertension Research and Treatments
- Asthma and respiratory diseases
- Polymer-Based Agricultural Enhancements
- Fibroblast Growth Factor Research
- Connexins and lens biology
- PARP inhibition in cancer therapy
- Regional Development and Environment
- RNA modifications and cancer
- Plant nutrient uptake and metabolism
- Advanced Decision-Making Techniques
Yangtze University
2025
Sichuan University
2013-2024
State Key Laboratory of Hydraulics and Mountain River Engineering
2022
Southern Medical University
2022
Nanfang Hospital
2022
Fujian Agriculture and Forestry University
2021
State Key Laboratory of Biotherapy
2013-2020
Chinese Academy of Geological Sciences
2015-2017
University of Nottingham Ningbo China
2013-2016
Institute of Agricultural Resources and Regional Planning
2016
Abstract CD38 is the main enzyme for nicotinamide adenine dinucleotide (NAD) degradation in mammalian cells. Decreased NAD levels are closely related to metabolic syndromes and aging-related diseases. Our study showed that deficiency significantly alleviated angiotensin II (Ang II)-induced vascular remodeling mice, as shown by decreased blood pressures; reduced media thickness, media-to-lumen ratio, collagen deposition; restored elastin expression. However, our bone marrow transplantation...
Populations of widespread species are usually geographically distributed through contrasting stresses, but underlying genetic mechanisms controlling this adaptation remain largely unknown. Here, we show that in Arabidopsis thaliana, allelic changes the cis-regulatory elements, WT box and W box, promoter a key transcription factor associated with oxygen sensing, RELATED TO AP 2.12 (RAP2.12), responsible for differentially regulating tolerance to drought flooding. These two cis-elements...
Abstract Knowledge about the drivers of benthic prokaryotic diversity and metabolic potential in interconnected coastal sediments at regional scales is limited. We collected surface across six zones covering ~200 km northern Zhejiang, East China Sea combined 16 S rRNA gene sequencing, community-level prediction, sediment physicochemical measurements to investigate variations composition with geographic distance under local environmental conditions. Geographic was most influential factor...
Emerging evidence has indicated that colony-stimulating factor-1 (CSF1) modulates neuroinflammation in the central nervous system and development of neuropathic pain, while underlying mechanism remains unknown. Here, we identified increased expression CSF1 derived from activated astrocytes ipsilateral dorsal horn rats with spinal nerve ligation (SNL). Suppression alleviated neuroinflammation, neuronal hyperexcitability, glutamatergic receptor subunit upregulation improved SNL-induced pain...
Elevated seawater temperature has altered the coupling between coastal primary production and heterotrophic bacterioplankton respiration. This shift, in turn, could influence feedback of ocean ecosystem to climate warming. However, little is known about how natural community responds increasing temperature. To investigate warming effects on community, we collected water samples from gradients (ranged 15.0 18.6 °C) created by a thermal flume coal power plant. The results showed that...
Coated controlled-release fertilizers (CRFs) have been widely applied in agriculture due to their increased efficiency. However, the widespread and a lot of coated CRFs application may leave undesired coating residues soil slow degradation. Limited information is available on effects substantial residual coatings bacterial community. By adding 0, 5, 10, 20, 50 times quantities from conventional amount resin water-soluble CRFs, we studied responses properties community composition these two...
Abstract Environmental factors impact species richness differently across taxonomic groups, and understanding the geographic patterns drivers influencing alpine plant remains limited. This study compiled global distribution data of 404 Gentiana , an genus, analyzed relative effects different environmental several previously proposed models on variation richness. By evaluating range size regions relationships between factors, we found that all tested had weak for wide‐ranging species, while...
Rationale: Pigment epithelium-derived factor (PEDF) is a 50 kD small secreting glycoprotein that participates in multiple physiological and pathological processes. Recent studies have reported PEDF plays an important role inflammatory responses several diseases. However, the of pathogenesis chronic obstructive pulmonary disease (COPD) remains unclear. Objective: The aim present study to explore potential relationship between COPD. Methods: We used differential proteomics – stable isotope...
Despite the numerous studies on large-scale patterns of species richness, spatial variation and determinants richness for alpine plant are still an outstanding question critical to future biodiversity conservation. The genus Saxifraga is a typical group with high in Himalaya-Hengduan mountain regions, China. We performed simple regression models variance partitioning assess importance different factors, especially soil-related ones, driving patterns. results showed that environmental energy,...
Given the facts that urban land is extremely limited and ecological environment protection confronted with severe challenges, it of great importance to effectively construct green infrastructure (GI) network identify relatively important landscape components. We identified prioritized GI centers in Fuzhou downtown area using MSPA connectivity evaluation. The least cost path method gravity model were used potential corridors at multiple levels. density analysis blind extract prioritize nodes...
Abstract The effects of contemporary climate, habitat heterogeneity and long-term climate change on species richness are well studied for woody plants in forest ecosystems, but poorly understood herbaceous plants, especially alpine–arctic ecosystems. Here, we aim to test if the previously proposed hypothesis based richness–environment relationship could explain variation patterns typical genus Saxifraga. Using a newly compiled distribution database 437 Saxifraga species, estimated all...
<b>Background:</b> IPF is a serious disease. It's believed the EMT process plays crucial role in pathogenesis of IPF, but mechanism for regulating isn't fully clear. Therefore, we explored new processes, which may provide ideas future drug development. In our previous study, have found that BLM-induced rhesus pulmonary fibrosis model, content TNKS significantly correlated with severity disease, while autophagy model group showed significant down-regulation relative to normal group....
Intensity-modulated radiotherapy (IMRT) is the most commonly used technology in oncology, which enables precise conformation of radiation dose to target volume and reduces risk damage adjacent normal structures. Nevertheless, it still inevitable for IMRT head neck cancer cause radiation-related toxic side effects, such as dry mouth, mucositis, oral dysarthria, taste disorder, osteonecrosis, trismus. Trismus one common late effects caused by nasopharyngeal carcinoma (NPC), seriously affects...