A5080802252- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Vascular Procedures and Complications
- Aortic Disease and Treatment Approaches
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Aortic aneurysm repair treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Coronary Interventions and Diagnostics
- Cardiovascular Effects of Exercise
- Cardiac, Anesthesia and Surgical Outcomes
- Central Venous Catheters and Hemodialysis
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiac and Coronary Surgery Techniques
- Antiplatelet Therapy and Cardiovascular Diseases
Erasmus MC
2017-2025
Erasmus University Rotterdam
2016-2020
Rotterdam University of Applied Sciences
2019
Vascular and bleeding complications remain a concern after transfemoral transcatheter aortic valve replacement (TAVR). The impact of the sheath type on these remains unclear.
Abstract Objectives To study safety and performance of the MANTA Vascular closure device (VCD) under real world conditions in 10 centers. Background The is a novel plug‐based for large bore arteriotomy closure. Methods We included all eligible patients who underwent transfemoral percutaneous procedures. Exclusion criteria were per operator's discretion severe calcification or marked tortuosity access vessel, presence obesity/cachexia systolic blood pressure above 180 mmHg. primary endpoint...
Abstract Objectives To evaluate the value of left vertebral artery filter protection in addition to current filter‐based embolic technology achieve complete cerebral during TAVR. Background The occurrence cerebrovascular events after transcatheter aortic valve replacement (TAVR) has fueled concern for its potential application younger patients with longer life expectancy. Transcatheter (TCEP) devices may limit periprocedural by preventing macro and micro‐embolization brain. Conventional TCEP...
In aortic stenosis, valvulo-arterial impedance (Zva) estimates the overall left ventricular afterload (valve and arterial component). We investigated association of Zva (≥5 versus <5 mm Hg mL-1 m-2) on quality life (QOL) exercise performance (EP) ≥1 year after transcatheter valve replacement (TAVR).The study population consists 250 TAVR patients in whom baseline follow-up QOL was prospectively assessed using EuroQOL-5-dimensions instruments; EP 192 who survived questionnaires related to...
Aims: The aim of this study was to investigate the total amount, size and heterogeneity debris captured among different transcatheter valve types while repositioning. Methods results: A 328 patients who underwent aortic implantation (TAVI) with SENTINEL cerebral embolic protection (CEP) at our centre were eligible. Histopathological semiquantitative analysis performed data entered into prospective database. TAVI either Evolut R/PRO (N=123), SAPIEN 3 (N=113) or Lotus (N=92). Capture occurred...
The MANTA vascular closure device (VCD) is dedicated to large bore access and associated with favorable results in selected study populations. Anatomical predictors for site complications are lacking.To evaluate a real-world population identify complications.All patients undergoing transfemoral transcatheter aortic valve replacement (TAVR) between January 2016 May 2020 were included. Baseline characteristics collected, pre-procedural computed tomography post-deployment femoral angiograms...
Background: We aimed to compare the rate of neurological events in patients with or without cerebral embolic protection (CEP) during transcatheter aortic valve replacement (TAVR). Methods and Results: Data on clinical end points including ≤30 days post-TAVR were collected for all who underwent transfemoral TAVR 2 academic tertiary care institutions. Patients matched through propensity scoring, which resulted 333 pairs versus CEP out a total 831 consecutive patients. The median age was 81...
To correlate dynamics in electrical conduction after transcatheter aortic valve implantation (TAVI) with need for permanent pacemaker (PPM) and assess implications early discharge.Daily electrocardiograms TAVI were analysed rhythm times correlated PPM. Transcatheter was performed 291 consecutive patients three contemporary heart designs: Medtronic CoreValve (n = 111), Edwards Sapien XT 29) 3 72), Boston Lotus 79). We considered two cohorts: (A) Patients normal baseline conduction; (B)...
We aimed to compare conduction dynamics and need for permanent pacemaker implantation (PPI) after CoreValve, Evolut R PRO (transcatheter aortic valve replacement (TAVR)). Patients were stratified based on at baseline; Cohort A had normal conduction, B abnormalities including atrioventricular (AV)-block, fascicular block or complete bundle branch block. Three different dynamic QRS-patterns defined: stable QRS-duration, transient QRS-prolongation persistent QRS-prolongation. performed...
Transcatheter aortic valve implantation (TAVI) is a less invasive replacement technique and indicated for patients with symptomatic severe stenosis high operative risk. Cerebral embolisation seems inherent to TAVI, as illustrated by the consistent appearance of new brain lesions on post-procedural MRI studies. Embolic protection devices may capture or deflect embolised material en route thus reduce TAVI-related injury. Histopathology studies captured debris revealed diverse aetiology...
ObjectivesA retrospective observational cohort study to report on contemporary indications of balloon aortic valvuloplasty (BAV).BackgroundAs for transcatheter valve replacement (TAVR) are increasing, BAV is reinforced as a bridging therapy.MethodsA total 47 consecutive patients who underwent in parallel an existing TAVR program was retrospectively assessed and clinical events during 1 year follow-up.ResultsThe following were distinguished: bridge destination therapy (BTD), urgent...
BACKGROUND: The optimal antithrombotic therapy after transcatheter aortic valve implantation (TAVI) is unsettled. Short and longer-term thromboembolic bleeding risk post TAVI remain high. Non-vitamin K oral anticoagulant drugs (NOAC) may be attractive but the implications of prolonged NOAC in this setting require further research. aim study was to assess HAS-BLED a contemporary population explore its correlation with effective complications or without (N)OAC.METHODS: This included 986...
To compare early clinical outcomes after transcatheter aortic valve implantation (TAVI) with three consecutive generations of self-expanding valves (SEVs).Clinical endpoints patients who underwent TAVI CoreValve, Evolut R or PRO were included in a prospective database.TAVI was performed CoreValve (n = 116), 160) 92). and showed tendency towards lower permanent pacemaker (PPI) rates compared to (CoreValve 27% vs 16% 18%, p 0.091). By multivariable regression analysis had significantly higher...
This article provides supplementary tables and figures to the research article: Frequency, Impact Predictors of Access Complications with Plug-Based Large-Bore Arteriotomy Closure - A patient level meta-analysis [1]. The data provide insight in type management access complications related plug-based MANTA vascular closure device (VCD) for large-bore catheter-based cardiovascular interventions. Since is mostly used transcatheter aortic valve replacement (TAVR) procedures, this also contains a...