A5076677228- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Cardiac pacing and defibrillation studies
- Advanced MRI Techniques and Applications
- Pain Management and Treatment
- Cardiac Structural Anomalies and Repair
- Medical Image Segmentation Techniques
- Coronary Interventions and Diagnostics
- Pulmonary Hypertension Research and Treatments
- Atrial Fibrillation Management and Outcomes
- Pain Mechanisms and Treatments
- Congenital Heart Disease Studies
- Cerebrovascular and Carotid Artery Diseases
- Transcranial Magnetic Stimulation Studies
- Medical Imaging Techniques and Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Musculoskeletal pain and rehabilitation
- Migraine and Headache Studies
- Cardiomyopathy and Myosin Studies
- Aortic aneurysm repair treatments
- Cardiovascular Effects of Exercise
- Cardiovascular Health and Disease Prevention
Cardialysis (Netherlands)
2016-2025
Erasmus MC
2014-2024
Centre de Recherches sur les Macromolécules Végétales
2024
Erasmus University Rotterdam
2013-2020
Ospedali Riuniti di Foggia
2017
University of Foggia
2017
Harvard University
1998-2012
Massachusetts General Hospital
2012
University Medical Center Utrecht
2012
Federico II University Hospital
2012
Spinal cord stimulation (SCS) is efficacious for pain due to injury of peripheral nerves, and therefore models mononeuropathy appear be particularly suitable an experimental approach the study mechanisms underlying clinical effect this mode treatment in chronic neuropathic pain. Virtually all previous studies on SCS have utilized acute nociceptive types stimuli explore attenuating effects SCS. In present we made use two supposedly painful neuropathy developed by Bennett Xie (1988) Seltzer et...
Importance Abbreviated dual antiplatelet therapy (DAPT) reduces bleeding with no increase in ischemic events patients at high risk (HBR) undergoing percutaneous coronary intervention (PCI). Objectives To evaluate the association of sex comparative effectiveness abbreviated vs standard DAPT HBR. Design, Setting, and Patients This prespecified subgroup analysis followed Management High Bleeding Risk Post Bioresorbable Polymer Coated Stent Implantation With an Standard Regimen (MASTER DAPT)...
Abstract Background Severe tricuspid regurgitation (TR) is independently associated with increased morbidity and mortality. Percutaneous transcatheter approaches may offer an alternative for patients not amenable to surgery. Methods TriCLASP a prospective, single‐arm, multicenter European post‐market clinical follow‐up study (NCT04614402) evaluate the safety performance of PASCAL system (Edwards Lifesciences) in severe or greater TR. At 30 days, composite major adverse events (MAEs)...
Abstract Background Data on the use of global longitudinal strain (GLS) for assessing patients who had undergone primary percutaneous coronary intervention (PCI) ST elevation myocardial infarction (STEMI) remains scarce. Purpose The aim this sub-analysis RESUS AMI trial was to evaluate feasibility and reproducibility artificial intelligence (AI)-assisted echocardiographic assessments in STEMI after PCI correlation with left ventricular ejection fraction (LVEF), volumes, infarct size assessed...
Paravalvular aortic leakage (PVL) after transcatheter valve implantation (TAVI) is a complication with potentially severe consequences. The relation between native root calcium burden, stent frame eccentricity and PVL was not studied before.Two-hundred-and-twenty-three consecutive patients stenosis who underwent TAVI Medtronic CoreValve System© had available pre-discharge transthoracic echocardiography were studied. Echocardiographic inflow defined as major-minor diameter in short-axis view...
Abstract Objectives To evaluate the value of left vertebral artery filter protection in addition to current filter‐based embolic technology achieve complete cerebral during TAVR. Background The occurrence cerebrovascular events after transcatheter aortic valve replacement (TAVR) has fueled concern for its potential application younger patients with longer life expectancy. Transcatheter (TCEP) devices may limit periprocedural by preventing macro and micro‐embolization brain. Conventional TCEP...
Abstract Childhood obesity continues to escalate worldwide and may affect left ventricular (LV) geometry function. The aim of this study was investigate the impact on prevalence hypertrophy (LVH) diastolic dysfunction in children. In analysis prospectively collected cross-sectional data children between 5 16 years age from randomly selected schools Peru, parameters LV function were compared according presence or absence (body mass index z-score > 2). LVH based (LVMI) adjusted for sex...
Significant paravalvular leakage (PVL) after transcatheter aortic valve implantation (TAVI) is related to patient mortality. Predicting the development of PVL has focused on computed tomography (CT) derived variables but literature targeting CoreValve devices limited, controversial, and did not make use standardized echocardiographic methods. The study included 164 consecutive patients with severe stenosis that underwent TAVI a Medtronic system©, available pre-TAVI CT pre-discharge...
The Lotus and SAPIEN3 are second-generation transcatheter heart valves, which designed to minimize paravalvular aortic regurgitation (PAR) after valve replacement (TAVR). We sought compare both devices for performance with emphasis on PAR by independent core laboratory analysis.A total of 162 (79 83 SAPIEN3) consecutive patients (51% female, 80 ± 8 years, Logistic EuroSCORE 14.8 9.4%) who underwent TAVR because stenosis were included. Patients valve-in-valve treatment excluded. Pre-discharge...
Ejection fraction is one of the most powerful determinants prognosis and a crucial parameter for determination cardiovascular therapies in conditions such as heart failure, valvular ischaemic disease. Among echocardiographic methods, 3D echocardiography has been attributed preferred its assessment, given an increased accuracy reproducibility. Full-volume multi-beat acquisitions are prone to stitching artefacts due arrhythmias require prolonged breath holds. Single-beat exhibit lower temporal...
Three-dimensional transesophageal echocardiography (TEE) is an excellent modality for real-time visualization of the heart and monitoring interventions. To improve usability 3-D TEE intervention catheter guidance, automated segmentation desired. However, still a challenging task due to complex anatomy with multiple cavities, limited field view, typical ultrasound artifacts. We propose segment all cavities within view multi-cavity active shape model (ASM) in conjunction tissue/blood...
SPINAL CORD STIMULATION (SCS) has been increasingly used in the treatment of ischemia caused by obliterative diseases extremities and cardiac circulation. The most promising effects have obtained when physicians suspect that a major vasospastic component underlies ischemic symptoms (e.g., as Raynaud's disease). Despite clinical success this method, little is known about mechanisms underlying pain relief it produces its anti-ischemic effects. Most earlier experimental studies normal animals...
✓ The physiological mechanisms responsible for pain relief caused by spinal cord stimulation (SCS) are essentially unknown and recent experimental data sparse. In the present study authors explored possible involvement of supraspinal in effects SCS applied rats with mononeuropathy produced sciatic nerve ligation according to method Bennett Xie or that Seltzer, et al. Confirming results a previous undertaken authors, thresholds early component flexor reflex (latency 8–12 msec), which is...
The purpose of this study was to assess left atrial (LA) function and myocardial mechanics in patients with degenerative mitral regurgitation (MR). Eighty MR twenty control subjects were included prospectively. LA volume (LAV) right (RA) (RAV) measured three-dimensional transthoracic echocardiography at three phases the cardiac cycle as maximal (LAVmax RAVmax), minimal (LAVmin RAVmin), before contraction (LAVpre-A RAVpre-A). From these volumes, active stroke (SV), distensibility, emptying...
Our aim was to illustrate the pragmatic use of pre-procedural multislice computed tomography (MSCT) facilitate fluoroscopy guidance transcatheter mitral valve interventions.A dedicated software package (3mensio Structural Heart) is used analyse MSCT studies and localise anatomical entities by which would otherwise be invisible (e.g., interatrial septum, paravalvular leaks, leaflets), provide optimal C-arm gantry angles crucial steps catheter-based interventions. For any given structure that...