- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver physiology and pathology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Reconstructive Surgery and Microvascular Techniques
- Head and Neck Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Hepatitis C virus research
- Mesenchymal stem cell research
- Renal Transplantation Outcomes and Treatments
- Mycobacterium research and diagnosis
- Abdominal vascular conditions and treatments
- Hepatitis B Virus Studies
- Lung Cancer Treatments and Mutations
- Tracheal and airway disorders
- Innovations in Medical Education
- Transplantation: Methods and Outcomes
- Cancer Immunotherapy and Biomarkers
- Viral-associated cancers and disorders
- Appendicitis Diagnosis and Management
- Abdominal Trauma and Injuries
- Tuberculosis Research and Epidemiology
- Cancer Diagnosis and Treatment
National Taiwan University Hospital
2015-2024
National Taiwan University
2014-2023
National Yang Ming Chiao Tung University
2016-2022
Vancouver Clinic
2021
Tri-Service General Hospital
2017-2018
Creative Research Enterprises (United States)
2016
Institute of Medical Biology
2016
University of Otago
2015
Whipps Cross University Hospital
2015
Barts Health NHS Trust
2015
Right hepatectomy for a living liver donor via pure minimally invasive approach is challenging procedure and only few cases have been reported. Between May 2013 August 2015, 13 patients underwent robotic right in our institute, 54 received open surgery. In this series, no conversion was conducted hepatectomy. The 2 groups shared similar blood loss (169 versus 146 mL), complication rates (7.7% 9.3%), recovery of function (peak alanine aminotransferase, 269 252 IU/mL). group needed longer...
Macrophages engulf oxidized-LDL (oxLDL) leading to accumulation of cellular cholesterol and formation foam cells, which is a hallmark atherosclerosis. Moreover, recent studies showed that free in macrophages activation NLRP3 inflammasome production interleukin-1β (IL-1β) has been linked atherosclerosis-associated inflammation. However, it not clear if associated with hepatic inflammation fibrosis the liver. In this study, we investigated association oxLDL portal vein inflammation,...
To examine the role of Epstein-Barr virus (EBV) in lymphoepithelial carcinoma salivary gland Hong Kong Chinese.Ten cases (eight parotid and two submandibular) were examined. In situ hybridisation was used to localise EBER RNA, immunohistochemical methods detect expression latent membrane protein 1 (LMP-1) EBV positive tumours, Southern blot analysis clonality where frozen tissue available.None had a history Sjögren's syndrome or histological evidence benign lesion. The IgA antibody titre...
Insulin-like growth factor, (IGF)-1, is produced mainly by the liver and plays important roles in promoting regulating metabolism. Previous study reported that development of hepatocellular carcinoma (HCC) was accompanied a significant reduction serum IGF-1 levels. Here, we hypothesized dysregulation microRNAs (miRNA) HCC can modulate expression post-transcriptionally.The miRNAs profiles dataset 29 patients were examined using illumina BeadArray. Specific miRNA (miR)-190b, which...
Human studies on the use of metformin as host-directed therapy (HDT) for tuberculosis (TB) are rare. We performed a nationwide cohort study to evaluate effect mitigating risk active TB among patients with diabetes mellitus (DM). Among newly diagnosed DM identified in Taiwan National Health Insurance Research Database, users, defined basis >90 cumulative daily doses within 1 year, and propensity-score-matched nonusers were selected. The primary outcome was incident TB, using diagnostic...
<h3>Objectives:</h3> To study the incidence and extent of submucosal tumor extension in hypopharyngeal cancer to evaluate impact on recurrence overall survival rates. <h3>Method:</h3> Fifty-seven resected specimens were studied detail from January 1986 December 1989 by use whole-organ, step—serial sectioning technique. <h3>Results:</h3> Three types could be identified. Type I was characterized a with smooth round contour that extended submucosally. The mucosa thereby elevated detectable...
Abstract Liver fibrosis represents the end stage of chronic liver inflammatory diseases and is defined by abnormal accumulation extracellular matrix in liver. Advanced results cirrhosis, failure, portal hypertension. transplantation has been most effective treatment for these diseases, but procedure limited shortage suitable donors. Mesenchymal stromal cells (MSCs) have shown great potential associated with fibrosis. This study aimed to evaluate therapeutic effect MSC-based cell as an...
Research has revealed that angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) may prevent cancers such as hepatocellular carcinoma (HCC). The comparative chemopreventive effects of ACEIs ARBs in high-risk populations with hepatitis B virus (HBV) or C (HCV) infection have yet to be investigated. From 2005 2014, HBV HCV cohorts hypertensive patients without HCC history were recruited from three linked national databases Taiwan, classified into two...
Survival after post-transplant recurrence of HCC is dismal, and almost all treatments for recurrent are off-labeled, without an extensive large-scale analysis. We aimed to delineate their post-recurrence courses define benchmarks comparing future treatment effectiveness.Three national databases, including health insurance, catastrophic illness, the cause death, were linked cohort establishment data collection during period from 2005 2016. Patients with ≥6 months transplant surgery under...
• Radical neck dissection was performed on 43 patients with nasopharyngeal carcinoma in whom persistent or recurrent cervical metastasis developed after radiotherapy. The pathologic nature of the tumor lymph nodes studied step serial sectioning entire radical specimen at 3-mm intervals. In 70% patients, more tumor-harboring were detected when compared clinical examination. extensive behavior metastases reflected by presence extracapsular spread and existence isolated clusters cells 35%...
Limited anatomical liver resection for hepatocellular carcinoma (HCC) is complicated in cirrhotic patients with centrally located HCC and limited reserve. We present a case of total laparoscopic left medial right ventroanterior sectionectomy performed using the intrahepatic Glissonian approach curative HCC. The patient was 69-year-old man 6.5-cm-diameter at segments 4, 5, 8 which compressing middle hepatic vein (MHV). Child–Pugh class A cirrhosis noted, 15-min retention rate indocyanine...
Abstract: With the advent of age Artificial Intelligence (AI), we seek to consider how AI could shape clinical examinations, specifically Objective Structured Clinical Examinations (OSCEs). OSCEs, whilst having its own limitations, be further enhanced with new technologies like help better assess and prepare our future clinicians. everchanging requirements on modern clinician, deliberate strengths weaknesses AI, need for emphasis different skills complement rather than resist tides change....