A5057157712- Tuberculosis Research and Epidemiology
- Organic Electronics and Photovoltaics
- Lung Cancer Treatments and Mutations
- Diabetes Treatment and Management
- Groundwater flow and contamination studies
- Trauma and Emergency Care Studies
- Organ Transplantation Techniques and Outcomes
- Conducting polymers and applications
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Health Systems, Economic Evaluations, Quality of Life
- Soil and Unsaturated Flow
- Pelvic and Acetabular Injuries
- Pneumocystis jirovecii pneumonia detection and treatment
- Dialysis and Renal Disease Management
- Quantum Dots Synthesis And Properties
- Groundwater and Isotope Geochemistry
- Metabolism, Diabetes, and Cancer
- Infectious Diseases and Tuberculosis
- High-Temperature Coating Behaviors
- Hydrology and Watershed Management Studies
- RNA Research and Splicing
- Neonatal Respiratory Health Research
- Hydraulic Fracturing and Reservoir Analysis
- Nephrotoxicity and Medicinal Plants
Chang Gung University of Science and Technology
2022-2024
National Taiwan University Hospital
2015-2024
Fudan University Shanghai Cancer Center
2024
University of Tennessee at Chattanooga
2023
Chi Mei Medical Center
2006-2022
Taichung Armed Forces General Hospital
2022
National Defense Medical Center
2020
Tri-Service General Hospital
2020
University of Florida
2019
Columbus Oncology and Hematology Associates
2019
This work presents polymer photovoltaic devices based on poly(3-hexylthiophene) (P3HT) and TiO2 nanorod hybrid bulk heterojunctions. Interface modification of a surface is conducted to yield very promising device performance 2.20% with short circuit current density (Jsc) 4.33 mA/cm2, an open voltage (Voc) 0.78 V, fill factor (FF) 0.65 under simulated A.M. 1.5 illumination (100 mW/cm2). The suppression recombination at P3HT/TiO2 interfaces by the attachment effective ligand molecules...
(1) Background: Lung cancer is silent in its early stages and fatal advanced stages. The current examinations for lung are usually based on imaging. Conventional chest X-rays lack accuracy, computed tomography (CT) associated with radiation exposure cost, limiting screening effectiveness. Breathomics, a noninvasive strategy, has recently been studied extensively. Volatile organic compounds (VOCs) derived from human breath can reflect metabolic changes caused by diseases possibly serve as...
Patients on anti-tuberculosis treatment may develop acute kidney injury (AKI), but little is known about the renal outcome and prognostic factors, especially in an aging population. This study aimed to calculate incidence of AKI due anti-TB drugs analyze outcomes predictors recovery.From 2006 2010, patients were identified their medical records reviewed. Acute was defined according criteria established by Network, while recovery as a return serum creatinine baseline. Predictors Cox...
Abstract Osteosarcoma is characterized by a high malignant and metastatic potential. The chemokine stromal‐derived factor‐1α (SDF‐1α) its receptor, CXCR4, play crucial role in adhesion migration of human cancer cells. Integrins are the major adhesive molecules mammalian cells, has been associated with metastasis Here, we found that osteosarcoma cell lines had significant expression SDF‐1 CXCR4 (SDF‐1 receptor). Treatment cells SDF‐1α increased surface αvβ3 integrin. CXCR4‐neutralizing...
In this study, we investigated the interplay of three-dimensional morphologies and photocarrier dynamics polymer/inorganic nanocrystal hybrid photoactive layers consisting TiO2 nanoparticles nanorods. Electron tomography based on scanning transmission electron microscopy using high-angle annular dark-field imaging was performed to analyze morphological organization nanocrystals in poly(3-hexylthiophene) (P3HT) optimal solar cell devices. The Three-dimensional (3D) these films were correlated...
Interleukin enhancer binding factor (ILF) is a human transcription and new member of the winged helix/forkhead family. ILF can bind to purine-rich regulatory motifs such as T-cell leukemia virus-long terminal region interleukin-2 promoter. Here we report 2.4 A crystal structure two DNA domains (FOXK1a) 16-bp duplex containing promoter sequence. Electrophoretic mobility shift assay studies demonstrate that ILF-DNA domain molecules cooperatively DNA. In addition recognition helix recognizing...
Having a secure and stable energy supply is top priority for the global community. Fuel-cell technology recognized as promising electrical generation system twenty-first century. Polyvinyl alcohol/zeolitic imidazolate framework-8 (PVA/ZIF-8) composite membranes were successfully prepared in this work from direct ZIF-8 suspension solution (0⁻45.4 wt %) PVA mixing to prevent filler aggregation methanol alkaline fuel cells (DMAFCs). The fillers chosen appropriate cavity size screening aid allow...
Human studies on the use of metformin as host-directed therapy (HDT) for tuberculosis (TB) are rare. We performed a nationwide cohort study to evaluate effect mitigating risk active TB among patients with diabetes mellitus (DM). Among newly diagnosed DM identified in Taiwan National Health Insurance Research Database, users, defined basis >90 cumulative daily doses within 1 year, and propensity-score-matched nonusers were selected. The primary outcome was incident TB, using diagnostic...
FOXP1 belongs to the P-subfamily of forkhead transcription factors and contains a conserved DNA-binding domain. According size exclusion chromatography analysis, domain existed as mixture monomer dimer. The dissociation constants wild-type, C61S, C61Y mutants were 27.3, 28.8, 332.0 μM, respectively. In contrast, A39P mutant formed only monomer. NMR analysis also showed that C61S mixture. solution structure A39P/C61Y was similar X-ray FOXP2 Comparison backbone dynamics residues preceding...
Patients with diabetes have a relatively high risk of fracture due to osteoporosis. However, the osteoporosis associated use oral hypoglycemic drugs and dipeptidyl peptidase-4 inhibitor (DPP-4i) by patients is unclear. This study aimed explore effect DPP-4i on in Taiwanese type 2 mellitus (T2DM).This enrolled 6339 (DPP-4i group) 25 356 without (non-DPP-4i group). They were matched 1:4 propensity score matching, using confounding variables including sex, age, comorbidities, medication, index...
Secondary pneumonia has a significant clinical impact on critically ill patients with COVID-19.
We have investigated the effect of polymer molecular weight on morphology and performance poly(3-hexylthiophene)/TiO2nanorod hybrid photovoltaic devices by using scanning near field optical microscopy (SNOM), atomic force (AFM) confocal Raman microscopy. From topography absorption mapping images, it is found that rod-like structure low film consists a large amount grain boundaries has less continuous image. In contrast, larger domain high exhibits image, as result enhanced stacking...
Acute kidney injury (AKI) is occasionally detected in patients receiving anti-tuberculosis (TB) treatment. This prospective cohort study the first to investigate incidence, risk factors, and renal outcomes of AKI during anti-TB was conducted from January 1, 2016, May 31, 2018. Patients with a new diagnosis TB on standard treatment were enrolled, received regular laboratory monitoring. defined according Kidney Disease: Improving Global Outcome (KDIGO) criteria. Urinalysis, ultrasonography,...
The association between tuberculosis (TB) and lung cancer is well known. However, carcinogenesis of TB its connection with epidermal growth factor receptor (EGFR) mutation remains unclear. This study aimed to determine this see if can affect the outcome patients cancer. a retrospective cohort receiving EGFR-tyrosine kinase inhibitors (TKIs) 1996 2010 using National Health Insurance Research Database Taiwan. Because therapeutic response was required apply EGFR-TKIs for >90 days, only...
Objectives: Therapy outcomes for newly diagnosed, critically ill lung cancer patients have seldom been evaluated.This study evaluated therapy treatment-naïve in the intensive care unit (ICU).Materials and Methods: Patients were excluded if they had previously received treatment, such as systemic chemotherapy, targeted therapy, radiotherapy, or surgical resection before ICU admission.The therapeutic strategies determined while ICU.The patients' demographic data, clinical outcomes,...
In this letter, the authors propose a practical and reliable approach—using deposited multiwalled carbon nanotubes (MWCNTs) as source drain electrodes—for reducing contact resistance (Rc) in pentacene-based bottom-contact thin-film transistors. The value of Rc devices was closely linked to resultant length MWCNTs; lowest 3×108Ωμm. largest saturation mobility 0.14cm2∕Vs; reached up three times higher when threshold voltage determined using maximum transconductance (Gm,max) extrapolation...
Background and objectives Chinese patients with ESRD have different comorbidity patterns than white require a validated index. The objective of this study was to develop new index for mortality prediction in 2006–2009 Taiwanese incident hemodialysis patients. Design, setting, participants, & measurements Data were retrieved from 2005 2010 Taiwan National Health Insurance claim records, follow-up available until December 31, 2010. same comorbid conditions as the US Renal System (USRDS) that...