A5004390792- Animal Nutrition and Physiology
- Hepatitis Viruses Studies and Epidemiology
- Viral gastroenteritis research and epidemiology
- Genetic and phenotypic traits in livestock
- Coccidia and coccidiosis research
- Complement system in diseases
- Aquaculture disease management and microbiota
- Veterinary medicine and infectious diseases
- Effects of Environmental Stressors on Livestock
- Pharmacological Effects of Natural Compounds
- Blood groups and transfusion
- Lipid metabolism and disorders
- Prion Diseases and Protein Misfolding
- Vector-Borne Animal Diseases
- Biochemical effects in animals
- Hepatitis B Virus Studies
- Metallurgy and Material Science
- Animal Diversity and Health Studies
- Reproductive Physiology in Livestock
- Vector-borne infectious diseases
- Antimicrobial Peptides and Activities
- Livestock and Poultry Management
- Moringa oleifera research and applications
- Bird parasitology and diseases
- Invertebrate Immune Response Mechanisms
Trakia University
2013-2024
African Swine Fever Virus (ASFV) is a high-consequence transboundary animal pathogen that often causes hemorrhagic disease in swine with case fatality rate close to 100%. Lack of treatment or vaccine for the makes it imperative safe and efficacious vaccines are developed safeguard industry. In this study, we evaluated immunogenicity seven adenovirus-vectored novel ASFV antigens, namely A151R, B119L, B602L, EP402RΔPRR, B438L, K205R A104R. Immunization commercial cocktail recombinant...
Infectious diseases cause devastating economic losses in the sheep industry. The current study aimed to evaluate blood serum concentrations of lysozyme, gamma interferon, immunoglobulin G, M, cortisol, serotonin, activity alternative pathway complement activation (APCA), and betalysin lambs, whose rations were supplemented with 4g /kg immunomodulator Immunobeta for 60 days - from 15th day 75th after birth manure-pasture cultivation during a thermoneutral, hot summer cold winter period. lambs...
(1) Background: Hepatitis E virus (HEV) is a causative agent of acute viral hepatitis, predominantly transmitted by the fecal-oral route. In developed countries, HEV considered to be an emerging pathogen since number autochthonous cases rising. disease with proven zoonotic potential for some its genotypes. The main reservoirs are domestic pigs and wild boar. Consumption undercooked meat, as well occupational exposure, key factors spread HEV. order evaluate risks future evolution, detailed...
Hepatitis E virus (HEV) causes epidemics in developing countries and is primarily transmitted through the fecal-oral route. There have been recent reports on zoonotic spread of virus, several animal species, pigs, recognized as reservoirs HEV. Because its possible spread, there an urgent need a method for cost-effective production HEV proteins that can be used diagnostic antigens serological detection anti-HEV antibodies.The open reading frame (ORF)2 protein was purified from plant tissue by...
Hepatitis E is an emerging global disease, mainly transmitted via the fecal–oral route in developing countries, and a zoonotic manner developed world. Pigs wild boar constitute primary virus (HEV) reservoir. Consumption of undercooked animal meat or direct contact with infected animals most common source HEV infection European countries. The purpose this study to develop enzyme immunoassay (EIA) for detection anti-hepatitis IgG pig serum, using plant-produced recombinant HEV-3 ORF2 as...
The aim of this work was to investigate the effect Ochratoxin A (OTA) and Silymarin on serum lysozyme concentrations, complement betalysin activity in broiler chickens. In experiment 144 one-day-old Ross 308 male chicks were used. All divided four groups 36 birds each: Group 1: Basal diet (BD) with no supplementation Silymarin; 2: BD 1.0% 3: 3.0 mg/kg OTA; 4: OTA plus Silymarin. It found that concentration 2nd group there is a significant difference 3 4. immunosuppressive underlined but...
Honey bees (Apis mellifera L.) are crucial pollinators for many crops and natural ecosystems. However, honey bee colonies have been experiencing heavy overwinter mortality in almost all parts of the world. In present study we investigatеd, first time, effects from application herbal supplements NOZEMAT HERB® (NH) HERB PLUS® (NHP) on overwintering colony survival total protein lysozyme content. To achieve this, early autumn 2019, 45 were selected treated with these supplements. The content...
The aim of the present investigation was to study impact Haberlea rhodopensis extract on innate immune response in rabbits. complement and lysozyme activity, percent phagocytosis, phagocytic index were studied. analysis results showed that treatment with extract, cyclophosphamide, KLH renders a remittent effect upon classical pathway activation system concentration rabbit blood serum. These same factors have no direct activity investigated animals. obtained data show limited rabbits’ natural...
Infectious diseases cause devastating economic losses in the sheep industry. The current study aimed to evaluate blood serum concentrations of lysozyme, gamma interferon, immunoglobulin G, M, cortisol, serotonin, activity alternative pathway complement activation (APCA), and β-lysine lambs, whose rations were supplemented with 2 g/kg Silymarin for 60 days – from 15th day 75th after birth manure-pasture cultivation during a thermoneutral, hot summer cold winter period. lambs divided into two...
The beta-lysine activity of blood serum and egg white in broilers broiler breeders from the ROSS 308 hybrid reared industrial conditions was studied using a photometric method. birds experimental groups were treated with polybacterial immunomodulator "AVIGEN", anti-stress preparation "ASPIVIT C" "BIOXAN", which helps to increase resorption surface intestinal mucosa.We found increased immunomodulator-treated broilers. No significant differences control parent herds until onset lay. On lay, we...
The rapiddissemination of scrapie over the past few decades led to development aspecific eradication programme, based on polymorphisms within prionprotein gene (PRNP). Current approach encourages selection ofanimals carrying resistant ARR/ARR genotype, while other genotypes areconsidered less preferable. Although strategy seems be working quitewell, farmers are concerned whether this will affect sheep productivity andsubsequently decrease net profits. current study was aimed elucidatethe...
Common carp is one of the most important commercially produced fish all around globe. Even not essential to fish, pro-nutrients could benefit animals’ health in many ways. Key role stock protection against pathogens played by complement system. The aim this study was investigate impact feed supplement VitaSil two major pathways activation – classical and alternative, extensively grown carp. initial level for Alternative pathway (APCA) among both groups 579.37 CH50. During first month...
Factors of non-specific immunity are responsible for protecting birds from a number viruses and bacteria. Bactericidal proteins played here lysozyme complement, interferon, as well beta-lysine. Adding appropriate active compounds to the bird's diet activate innate immune response subject studies by many authors. The practical application influence "Avigen Duck". immunomodulator in cultivation White Pekin ducks aims clarify dynamics indicators. It was found that treated with had higher...
Field trials were carried out to investigate the impact of “AVIGEN DUCK” immunomodulator on IFN-γ concentration, IL-2, IL-6, lysozyme, and betalysine activity in blood serum White Pekin ducks’ parents. The IFN-γ, IL-6 analyzed by immunoenzyme methods, while lysozyme beta-lysine activities determined using conventional techniques. measured values among experimental birds for most parameters significantly higher than those controls during observed period. An exception this trend concentrations...
Five rabbit populations of New Zealand White (NZW), Californian (CAL), crossbred NZW×GW and two generations the synthetic population – SPF<sub>1</sub> SPF<sub>2</sub> reared in Bulgaria were included present study with aim detecting genetic variability growth hormone encoding gene (<em>GH</em>) via polymerase chain reaction restriction fragment length polymorphism analysis direct sequencing. The targeted region <em>GH</em> was amplified a total...