Le Zhang

ORCID: 0000-0003-1887-5326
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Cancer-related molecular mechanisms research
  • Circular RNAs in diseases
  • MicroRNA in disease regulation
  • Retinal Imaging and Analysis
  • Epigenetics and DNA Methylation
  • Glaucoma and retinal disorders
  • Retinal Diseases and Treatments
  • RNA modifications and cancer

Obstetrics and Gynecology Hospital of Fudan University
2021

Inner Mongolia Medical University
2020

Taishan Medical University
2017-2018

Changhai Hospital
2014

Second Military Medical University
2014

Brahma-related gene 1 (BRG1) and long non-coding RNAs (lncRNAs) play important roles in cellular processes. However, little is known regarding their thoracic aortic aneurysms. We investigated BRG1 expression aneurysms the of lncRNA HIF alpha-antisense RNA regulating proliferation apoptosis smooth muscle cells vitro. mRNA protein human media specimens were examined by quantitative real-time polymerase chain reaction, immunohistochemical staining western blot. was up-regulated lentiviral...

10.1093/ejcts/ezu215 article EN European Journal of Cardio-Thoracic Surgery 2014-05-29

Abstract Purpose The aim of our study was to validate the sway long noncoding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) on metabolism and growth bladder cancer cells by microRNA‐31 (miR‐31)/cyclin‐dependent kinase ( CDK1 ). Methods Gene Expression Omnibus database used for analyzing differentially expressed lncRNA messenger (mRNA) in tissues, with highly PVT1 mRNA screened out. expression level detected quantitative reverse‐transcription polymerase chain reaction, cell...

10.1002/jcp.27279 article EN Journal of Cellular Physiology 2018-10-14

Purpose: To evaluate the therapeutic efficacy of conbercept for treatment diabetic macular edema (DME) with different baseline visual acuity.Methods: This is a retrospective, comparative study. A total 107 eyes patients were included. According to levels best corrected acuity (BCVA) and regimen, DME divided into four groups: subgroup worse VA (less than 69 letters, Snellen equivalent, 20/50 or worse; n = 37), untreated VA(n 28); better (78 20/32 20/40; 25), (n 17). Patients received one...

10.1080/02713683.2017.1379542 article EN Current Eye Research 2017-12-21
Coming Soon ...