A5100618510- Nerve injury and regeneration
- Reconstructive Surgery and Microvascular Techniques
- Traumatic Ocular and Foreign Body Injuries
- Facial Trauma and Fracture Management
- Neurogenesis and neuroplasticity mechanisms
- Obstructive Sleep Apnea Research
- Cleft Lip and Palate Research
- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Lipoproteins and Cardiovascular Health
- Allergic Rhinitis and Sensitization
- Nerve Injury and Rehabilitation
- Acute Myocardial Infarction Research
- Cancer Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Traumatic Brain Injury and Neurovascular Disturbances
- Electrospun Nanofibers in Biomedical Applications
- Urticaria and Related Conditions
- Tendon Structure and Treatment
- Orthopedic Surgery and Rehabilitation
- Bone health and treatments
- Cellular Mechanics and Interactions
- Bone and Joint Diseases
- Reconstructive Facial Surgery Techniques
- Tracheal and airway disorders
Hospital de São João
2003-2024
Hospital Braga
2023
Centre des Sciences du Goût et de l'Alimentation
2015
Centre National de la Recherche Scientifique
2015
Université de Bourgogne
2015
Fernando Pessoa University
2014
Universidade do Porto
2004-2010
Aesthetic Surgery Center
2005
Background: Fractures of the facial skeleton are relatively uncommon in children and adolescents, only a few reports review significant number patients. The authors performed retrospective study to analyze different characteristics such fractures pediatric population Portugal. Methods: reviewed clinical records series 912 patients 18 years age or younger with treated by Departments Plastic, Reconstructive, Aesthetic Surgery Maxillofacial Surgery, São João Hospital, Porto, Portugal, between...
The healing process of the skin is a dynamic procedure mediated through complex feedback growth factors secreted by variety cells types.Despite most recent advances in wound management and surgical procedures, these techniques still fail up to 50%, so cellular therapies involving mesenchymal stem (MSCs) are nowadays promising treatment ulcers which cause high morbidity.The MSCs modulate inflammatory local response induce cell replacing, paracrine mode action, being an important therapy for...
O presente projeto explora as vulnerabilidades em saúde nas áreas de risco, com foco no bairro Granja Guarani, localizado Teresópolis, estado do Rio Janeiro. objetivo principal é desenvolver uma estratégia evacuação para atender populações vulneráveis, principalmente famílias membros idosos, acamados ou deficiências físicas e cognitivas. Trata-se pesquisa observacional, campo abordagem transversal. A incluiu visitas domiciliares, coleta dados por meio entrevistas observação direta, além da...
The purpose of this study was to test in vivo two different nerve guides for promoting regeneration across a 10-mm gap the rat sciatic nerve: 1) one made PLGA novel proportion (90:10) polymers poly(L-lactide):poly(glycolide); 2) another (DL-lactide-epsilon-caprolactone) copolyester (Neurolac) tube, by comparing its healing efficacy with that more traditional methods end-to-end suture and autologous graft. Motor sensory functional recovery were assessed throughout period 20 weeks, repaired...
Abstract Peripheral nerves possess the capacity of self-regeneration after traumatic injury but extent regeneration is often poor and may benefit from exogenous factors that enhance growth. The use cellular systems a rational approach for delivering neurotrophic at nerve lesion site, in present study we investigated effects enwrapping site end-to-end rat sciatic repair with an equine type III collagen membrane enriched or not N1E-115 pre-differentiated neural cells. After neurotmesis, was...
To determine the pattern of occurrence mandibular fractures in pediatric population Portugal.This retrospective study reviews records patients 18 years age or younger from 10-year period 1993 to 2002. Age, gender, anatomic site, cause accident, weekly and monthly variation, location type fractures, presence associated injuries, treatment methods, complications were reviewed.During this period, 521 with 681 treated. Motor-vehicle accident (MVA) was most common (53.9% patients) fracture....
Poly(lactic-co-glycolic acid) (PLGA) nerve tube guides, made of a novel proportion (90:10) the two polymers, poly(L-lactide): poly(glycolide) and covered with neural cell line differentiated in vitro, were tested vivo for promoting regeneration across 10-mm gap rat sciatic nerve. Before testing, PLGA 90:10 tubes vitro water uptake mass loss compared collagen sheets. The was lower, more rapid higher than those sheets when immersed phosphate-buffered saline (PBS) solution. pH values immersing...
Abstract The goal of the present study was to assess whether in vitro‐differentiated N1E‐115 cells supported by a collagen membrane would enhance rat sciatic nerve regeneration after crush injury. To set up an appropriate experimental model for investigating effects neural cell transplantation, we have recently described sequence functional and morphologic changes occurring standardized injury with nonserrated clamp. Functional recovery evaluated using index, static extensor postural thrust,...
Abstract Advances in neonatal care have led to an increase the survival rate of children with large congenital diaphragmatic defects. Reconstruction by direct closure is not usually possible and surgical correction newborn consists synthetic patch closure. Recurrence complications are high this technique a latter reconstruction living tissue now advocated. We report case hernia treated initially 10 months latter, after recurrence, reinnervated reverse latissimus dorsi (RLD) flap. used...
BonelikeÒ graft that mimics the inorganic composition of bone tissue has been developed and characterized over last decade. To evaluate osteoconductivity two granule size ranges, one ranging from 150-250µm other 250-500µm were implanted in femurs New Zealand White rabbits, aiming at being clinically used different medical applications, such as dentistry orthopaedics. In order to facilitate application use a commercially available polymeric vehicle was also analyzed. Radiological examination,...
Abstract Chewing skills develop greatly during the two first years of life, but evolution masticatory efficiency has never been directly measured so far. A bottleneck for such study is difficulty in using chew‐and‐spit method with infants and very young children. Herein, we propose a new based on model gel enclosed food feeder, which assessed adult subjects. Subjects chewed compressed either alone or different feeders. Analysis number particles particle area distribution revealed that one...
Impacted injuries of the head and neck are uncommon. Associated can be present a serious problem. We an unusual clinical case discuss management this complex injury. Head deserve special attention because their enormous functional esthetic significance. Contusion, abrasion, retained foreign bodies, laceration, avulsion some most frequent injuries. Impalement not so common. These lesions combine aspects blunt penetrating trauma usually result from penetration by large, rigid, blunt-tipped...