A5015729010- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Digestive system and related health
- Veterinary medicine and infectious diseases
- Gastric Cancer Management and Outcomes
- Gastrointestinal motility and disorders
- Microscopic Colitis
- Inflammatory Bowel Disease
- Diet and metabolism studies
- Celiac Disease Research and Management
- Gastrointestinal disorders and treatments
- Infant Health and Development
- Congenital gastrointestinal and neural anomalies
- Immunodeficiency and Autoimmune Disorders
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Radiomics and Machine Learning in Medical Imaging
- Antifungal resistance and susceptibility
- Pediatric health and respiratory diseases
- Pancreatitis Pathology and Treatment
- Atomic and Subatomic Physics Research
- Inflammation biomarkers and pathways
- Biosimilars and Bioanalytical Methods
- Complementary and Alternative Medicine Studies
Rabin Medical Center
2016-2025
Holon Institute of Technology
2022-2024
Ariel University
2021-2023
Tel Aviv University
2012-2022
Clalit Health Services
2017
Bar-Ilan University
2009
Israel Ministry of Health
2009
Sheba Medical Center
2009
Background Data on the association of Helicobacter pylori infection and BMI are conflicting. The fact that both H. associated with low socioeconomic status (SES) makes this relationship difficult to characterize. Materials methods We aimed evaluate between after adjusting for multiple covariates. analyzed a cohort 235 107 individuals aged 18 years or older, who performed 13 C urease breath test ( C-UBT), from 2007 2014. BMI, age, sex, SES, ethnicity, medications were extracted nationwide...
ABSTRACT Background Proton pump inhibitors (PPI) for gastroesophageal reflux disease (GERD) are associated with a high failure rate. Our uncontrolled feasibility study aimed determining the effect of transcutaneous electrical stimulation system (TESS) on GERD symptoms and acid exposure time (AET). Methods Recruited patients heartburn regurgitation. During first phase (one‐week, run‐in period, off‐PPI's), completed symptom diaries demographic questionnaires. Thereafter, all underwent...
The current guidelines recommend culture and antibiotic susceptibility testing of Helicobacter pylori following two failed eradication attempts. Where is unavailable, epidemiological data for secondary H. resistance are essential to allow the rational use antibiotics. aim this study was describe temporal changes in among adults previously treated infections identify predictors resistance. Between 2007 2014, consecutive patients undergoing gastroscopy with at our institution least treatment...
Rifaximin is a minimally absorbed antibiotic with high luminal activity, used to treat various gastrointestinal diseases. Although rifaximin has been proposed as first line treatment for small intestinal bacterial overgrowth (SIBO), few data are available regarding its efficacy in non-IBS subjects. We aimed assess the ability of normalize lactulose-H2 breath tests subjects symptoms suggestive SIBO.Consecutive patients presenting bloating and flatulence were prospectively recruited submitted...
There is no gold standard to assess adherence gluten-free diet (GFD) among patients with celiac disease (CeD). Gluten immunogenic peptides (GIPs) in urine and stool were suggested as novel markers for evaluating GFD. Our aim was the presence of GIP pediatric CeD, compare results alternative methods GFD adherence.Pediatric diagnosed who on at least 1 year, enrolled followed prospectively between November 2018 January 2021. Study visits included clinical assessment, a dietitian interview,...
Objectives The aim of this preliminary study was to compare the effectiveness domperidone and acupuncture for management diabetic gastroparesis. Methods This a preliminary, prospective non-randomised, unblinded case-crossover conducted in patients with longstanding, uncontrolled diabetes mellitus All received (20 mg four times day) 12 weeks, followed by 2–3 week washout period, then biweekly treatments 8 weeks. Gastric emptying rate, glucose glycated haemoglobin (HbA1C) levels were measured...
Background Threshold values for 13 C‐urea breath test (13C‐ UBT ) positivity may be affected by various sociodemographic, host, bacterial, and laboratory factors. Manufacturer recommended cutoffs 13C‐ assays not applicable in all settings. Optimizing have profound public health ramifications. We aimed to determine the optimal threshold our population. Methods Consecutive samples collected at central from patients undergoing a first‐time between 1 January 2010 31 December 2015 were included....
ABSTRACT Polyomavirus BK (BKV) establishes latent infection in various human tissues, including the kidney. Reactivation following renal transplantation (RT) may cause BKV-associated nephropathy, leading to graft loss. BKV reactivation is often associated with extensive rearrangements noncoding regulatory region (NCRR). We explored formation and predominance of versus diversity by cloning characterizing PCR-amplified NCRR sequences from six Israeli RT patients. found a high frequency degree...
Evidence regarding the risk of immunogenicity in patients with inflammatory bowel disease (IBD) who switched anti-tumor necrosis factor alpha (anti-TNFα) therapies to a subsequent anti-TNFα (either infliximab or adalimumab) is conflicting. We aimed assess consecutive large cohort patients.This was multicenter retrospective study. Medical records adult and pediatric IBD switchers had pharmacokinetic data for both agents between 2014 2020 were retrieved. Data including age, sex, type, duration...
Multiple studies in patients with Crohn's disease (CD) treated anti-tumor necrosis factor alpha agents have shown that proactive therapeutic drug monitoring (TDM) during the maintenance phase leads to improved outcomes. We aimed assess whether accelerated (IFX) administration induction resulted
Due to lower operational costs, health maintenance organizations (HMOs) may prioritize
Background . There are continual efforts to identify factors which influence the success of first-line therapy for Helicobacter pylori ( H. ) infection. The 13 C-urea breath test result (C13-UBT) utilizes urease activity and is a highly accurate diagnostic assay. We aimed determine whether magnitude C13-UBT related treatment success. Methods Adult patients who underwent first-time between January 2010 2016 were included. In order isolate naïve test-and-treat population unlikely have...
Helicobacter pylori has been associated with hyperemesis gravidarum in some geographical regions. The prevalence of H. Arab Israeli women the Upper Galilee and its association not studied previously. We aimed to examine if is this population.Subjects carrying a singleton fetus were recruited prospectively. Women an uncomplicated pregnancy served as controls. All patients underwent (13)C-urea breath testing assess for infection.A total 72 subjects, including 24 48 controls, aged 28.8±5.3...
<b><i>Introduction:</i></b> Adherence to the Mediterranean diet (MD) was shown be associated with decreased disease activity in adult patients Crohn’s (CD). Nevertheless, data on its association fecal calprotectin (FC), particularly children, remain limited. This study aimed assess between adherence MD and FC as an indicator of mucosal healing who are predominantly remission while undergoing biological therapy. <b><i>Methods:</i></b> a...
Background The accuracy and repeatability of breath test in the diagnosis Helicobacter pylori infection have not been adequately investigated. Although it has shown that storage for long periods does affect analysis results, no data are available on effect repetitive testing. In this study, our aim was to evaluate analyses samples at room temperature. Methods A total 202 positive were collected duplicates, before after administration 75 mg 13 C‐ urea dissolved 100 ml orange juice. Breath...
<b><i>Introduction:</i></b> Suppression of gastric acid secretion with proton-pump inhibitors (PPI) is an integral part the treatment <i>Helicobacter pylori</i> infection. Esomeprazole has been shown to be superior other PPIs when used in context triple therapy; however, comparative data for PPI efficacy quadruple therapy are lacking. Current guidelines recommend <i>H. eradication areas high clarithromycin resistance....
Clarithromycin resistance is the most common cause of Helicobacter pylori treatment failure and it attributed to three point mutations, A2142G, A2142C A2143G, within 23S rRNA gene. We aimed determine prevalence H. clarithromycin using a novel high resolution melt assay. A total 151 stool samples were collected from treatment-naïve patients with general gastric discomfort who also performed 13CO2 breath tests. Stool antigen tests on 126 collected. Bacterial DNA was extracted analyzed by...