A5073299716- Photosynthetic Processes and Mechanisms
- Mitochondrial Function and Pathology
- Animal Genetics and Reproduction
- CRISPR and Genetic Engineering
- ATP Synthase and ATPases Research
- Plant nutrient uptake and metabolism
- Viral Infectious Diseases and Gene Expression in Insects
- Metalloenzymes and iron-sulfur proteins
- Chromosomal and Genetic Variations
- Toxin Mechanisms and Immunotoxins
- Animal Disease Management and Epidemiology
- Transgenic Plants and Applications
Seoul National University
2024-2025
Pohang University of Science and Technology
2022-2023
Molina Center for Energy and the Environment
2023
Livestock, particularly cattle, are crucial for biotechnology fields, such as genetic breeding, infectious diseases, bioreactors, and specific disease models. However, engineering in cattle has lagged due to long gestation periods, single embryo pregnancies, high rearing costs. Additionally, the slow validation of germline transmission absence germline-competent embryonic stem cells hinder progress. With development genome editing technologies like ZFN, TALEN, CRISPR-Cas9, recent...
Initially discovered in yeast, mitochondrial retrograde signalling has long been recognised as an essential the perception of stress by eukaryotes. However, how to maintain optimal amplitude and duration its activation under natural conditions remains elusive plants. Here, we show that TaSRO1, a major contributor agronomic performance bread wheat plants exposed salinity stress, interacted with transmembrane domain-containing NAC transcription factor TaSIP1, which could translocate from...
Plants have long been considered a cost-effective platform for recombinant production. A recently recognized additional advantage includes the low risk of contamination human pathogens, such as viruses and bacterial endotoxins. Indeed, great advance has made in developing plants “factory” to produce proteins use biopharmaceutical purposes. However, there is still need develop new tools protein production plants. In this study, we provide data showing that B1 domain Streptococcal G (GB1) can...
ABSTRACT Protein biogenesis is a complex process, and complexity greatly increased in eukaryotic cells through specific targeting of proteins to different organelles. To direct targeting, organellar carry an organelle‐specific signal for recognition by import machinery. However, the situation confusing transmembrane domain (TMD)‐containing signal‐anchored (SA) various organelles because TMDs function as endoplasmic reticulum (ER) signal. Although ER SA well understood, how they are targeted...
Abstract Chloroplasts and mitochondria are subcellular organelles that evolved from cyanobacteria α-proteobacteria, respectively. Although they have their own genomes, the majority of proteins encoded by nuclear genes, translated cytosolic ribosomes, imported via outer inner membrane translocon complexes. The unfolding mature regions is thought to be a prerequisite for import into these organelles. However, it not fully understood how protein folding properties affect In this study, we...
Abstract Plant cells have two endosymbiotic organelles, chloroplasts, and mitochondria. These organelles perform specific functions that depend on organelle‐specific proteins. The majority of chloroplast mitochondrial proteins are specifically imported by the transit peptide presequence, respectively. However, a significant number also dually targeted to these organelles. Currently, it is not fully understood how both chloroplasts In this study, mechanism underlying targeting dual AtSufE1 in...
<title>Abstract</title> Background Livestock, particularly cattle, are crucial for biotechnology fields, such as genetic breeding, infectious diseases, bioreactors, and specific disease models. However, engineering in cattle has lagged due to long gestation periods, single embryo pregnancies, high rearing costs. Additionally, the slow validation of germline transmission absence germline-competent embryonic stem cells hinder progress. With development genome editing technologies like ZFN,...