A5041281706- Plant Molecular Biology Research
- Plant Reproductive Biology
- Photosynthetic Processes and Mechanisms
- Plant nutrient uptake and metabolism
- Light effects on plants
- Plant Stress Responses and Tolerance
- Polysaccharides and Plant Cell Walls
- Calcium signaling and nucleotide metabolism
- Advanced biosensing and bioanalysis techniques
- Plant Gene Expression Analysis
- Synthesis and Biological Evaluation
- Plant responses to water stress
- Protein Tyrosine Phosphatases
- Child and Adolescent Psychosocial and Emotional Development
- Molecular Sensors and Ion Detection
- Phytase and its Applications
- Ubiquitin and proteasome pathways
- Legume Nitrogen Fixing Symbiosis
- Orthopedic Infections and Treatments
- Mass Spectrometry Techniques and Applications
- Soybean genetics and cultivation
- Early Childhood Education and Development
- Adenosine and Purinergic Signaling
- Genomics and Chromatin Dynamics
- Plant Parasitism and Resistance
Hebei Normal University
2012-2025
Pennsylvania State University
2022
Ministry of Education of the People's Republic of China
2016
Carnegie Institution for Science
2008-2014
Carnegie Department of Plant Biology
2005-2011
University of California, San Francisco
2008
Institute of Botany
2008
Chinese Academy of Sciences
2008
Nankai University
2008
Technische Universität Dresden
2007
Brassinosteroid (BR) homeostasis and signaling are crucial for normal growth development of plants. BR through cell-surface receptor kinases intracellular components leads to dephosphorylation accumulation the nuclear protein BZR1. How regulates gene expression, however, remains unknown. Here we show that BZR1 is a transcriptional repressor has previously unknown DNA binding domain binds directly promoters feedback-regulated biosynthetic genes. Microarray analyses identified additional...
Brassinosteroids (BRs) bind to the extracellular domain of receptor kinase BRI1 activate a signal transduction cascade that regulates nuclear gene expression and plant development. Many components BR signaling pathway have been identified studied in detail. However, substrate transduces downstream remains unknown. Proteomic studies plasma membrane proteins lead identification three homologous BR-signaling kinases (BSK1, BSK2, BSK3). The BSKs are phosphorylated by vitro interact with vivo....
As the major mechanism of plant growth and morphogenesis, cell elongation is controlled by many hormonal environmental signals. How these signals are coordinated at molecular level to ensure coherent cellular responses remains unclear. In this study, we illustrate a circuit that integrates all growth-regulating signals, including auxin, brassinosteroid, gibberellin, light, temperature. Analyses genome-wide targets, genetic biochemical interactions demonstrate auxin-response factor ARF6,...
Abstract In rice (Oryza sativa), brassinosteroids (BRs) induce cell elongation at the adaxial side of lamina joint to promote leaf bending. We identified a mutant (ili1-D) showing an increased inclination phenotype similar that caused by BR treatment. The ili1-D overexpresses HLH protein homologous Arabidopsis thaliana Paclobutrazol Resistance1 (PRE1) and human Inhibitor DNA binding proteins. Overexpression RNA interference suppression ILI1 increase reduce, respectively, laminar inclination,...
Light and brassinosteroid (BR) antagonistically regulate the developmental switch from etiolation in dark to photomorphogenesis light plants. Here, we identify GATA2 as a key transcriptional regulator that mediates crosstalk between BR- light-signaling pathways. Overexpression of causes constitutive dark, whereas suppression reduces caused by light, BR deficiency, or mutant cop1. Genome profiling chromatin immunoprecipitation experiments show directly regulates genes respond both BR....
Abstract Expression of two Arabidopsis (Arabidopsis thaliana) apyrase (nucleoside triphosphate-diphosphohydrolase) genes with high similarity, APY1 and APY2, was analyzed during seedling development under different light treatments using β-glucuronidase fusion constructs the promoters both genes. As evaluated by staining independently confirmed other methods, highest expression apyrases in rapidly growing tissues and/or that accumulate auxin levels. Red-light treatment etiolated seedlings...
Significance Reversible ubiquitination regulates cellular protein abundance. The receptor-like kinase (RLK) RGFR1 plays an important role in regulating root meristem development. Upon ligand binding, activated is ubiquitinated and eventually degraded by the 26S proteasome. In this study, we found that ubiquitin-specific proteases UBP12 UBP13 are components of signaling pathway. interacts directly with can counteract ligand-induced degradation RGFR1. Our discovery provides insight into...
Starch is the major storage carbohydrate in plants and functions buffering carbon energy availability for plant fitness with challenging environmental conditions. The timing extent of starch degradation appear to be determined by diverse hormonal signals; however, our understanding regulation metabolism fragmentary. Here, we demonstrate that phytohormone brassinosteroid (BR) redox signal hydrogen peroxide (H2O2) induce breakdown guard cells, which promotes stomatal opening. BR-insensitive...
Significance Upon brassinosteroid (BR) treatment, BRASSINAZOLE RESISTANT1 (BZR1) is dephosphorylated and accumulate in the nucleus. However, it was unclear whether these two processes are interdependent. Here, we show that BR signaling first recruits phosphorylated BZR1 to nucleus where by protein phosphatase 2A (PP2A). constitutively degraded via a BR- 26S proteosome–independent mechanism; however, treatment activates different proteosome–dependent pathway increases turnover rate. These...
Abstract Seed size is determined by the coordinated growth of embryo, endosperm, and integument. Growth integument initiated signal molecules released from developing endosperm or embryo. Although recent studies have identified many components that regulate seed controlling growth, upstream signals transduction pathway activate these after double fertilization are unclear. Here, we report receptor-like kinase ERECTA (ER) controls regulating outer cell proliferation in Arabidopsis thaliana....
Abstract ATP, which is present in the extracellular matrix of multicellular organisms and fluid unicellular organisms, has been shown to function as a signaling molecule animals. The concentration ATP (xATP) known be functionally modulated part by ectoapyrases, membrane-associated proteins that cleave γ- β-phosphates on xATP. We data showing previously unreported (to our knowledge) linkage between apyrase phosphate transport. An from pea (Pisum sativum) complements yeast (Saccharomyces...
Abstract Brassinosteroids (BRs) play important roles in regulating plant reproductive processes. BR signaling or biosynthesis null mutants do not produce seeds under natural conditions, but the molecular mechanism underlying this infertility is poorly understood. In study, we report that outer integument growth and embryo sac development were impaired ovules of Arabidopsis thaliana receptor mutant bri1‐116 . Gene expression RNA‐seq analyses showed INNER NO OUTER ( INO ), an essential...
Abstract The phytochrome (phy) family of sensory photoreceptors modulates developmental programs in response to ambient light. Phys also control gene expression part by directly interacting with the bHLH class transcription factors, PHYTOCHROME-INTERACTING FACTORS (PIFs), and inducing their rapid phosphorylation degradation. Several kinases have been shown phosphorylate PIFs promote However, phosphatases that dephosphorylate are less understood. In this study, we describe 4 regulatory...
ABSTRACT Pollen development and germination are critical for successful generation of offspring in plants, yet they highly susceptible to heat stress (HS). However, the molecular mechanism underlying this process has not been fully elucidated. In study, we highlight essential roles two mRNA capping enzymes, named Arabidopsis phosphatase (ARCP) 1 2, regulating male female gamete development. The transmission efficiencies gametes carrying arcp1 arcp2 from +/− −/− mutants 30% zero,...
Protein phosphorylation, especially serine/threonine and tyrosine plays significant roles in signalling during plant growth development as well responses to biotic or abiotic stresses. Dual-specificity protein phosphatases dephosphorylate components of these pathways. Here, we report that an atypical dual-specificity phosphatase, AtPFA-DSP3 (DSP3), negatively affects the response plants high-salt conditions. A DSP3 loss-of-function mutant showed reduced sensitivity salt treatment. was...
Exposure to adverse childhood experiences (ACEs) is a global public health concern that detrimental the psychological outcomes of Chinese children in rural areas due lack awareness ACEs and mental resources. The objective this study was identify patterns impact ACE on depression suicidal ideation among 4683 students (mean age = 10.08 years, SD 0.99; 48.17% female students) from 63 elementary schools Guizhou Province, China. Latent class analysis conducted best pattern. A three-step approach...