A5088093411- Esophageal Cancer Research and Treatment
- Angiogenesis and VEGF in Cancer
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Gastric Cancer Management and Outcomes
- Lung Cancer Treatments and Mutations
- Esophageal and GI Pathology
- Circular RNAs in diseases
- RNA modifications and cancer
- Advanced biosensing and bioanalysis techniques
- MicroRNA in disease regulation
- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Advanced Nanomaterials in Catalysis
- Tracheal and airway disorders
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- Cardiac Structural Anomalies and Repair
- Brain Metastases and Treatment
- Myasthenia Gravis and Thymoma
- Fatigue and fracture mechanics
- Trauma Management and Diagnosis
- Aortic Disease and Treatment Approaches
Fujian Provincial Hospital
2015-2025
Fujian Medical University
2012-2025
Fuzhou University
2025
82th Hospital of Pla
2006
Second Military Medical University
2004-2006
Changhai Hospital
2004
Beth Israel Deaconess Medical Center
2003
Angiogenesis Foundation
2001
Harvard University
2001
Hadassah Medical Center
2001
Background Circular RNAs (circRNAs) play an important role in tumorigenesis and several circulating circRNA signatures are closely associated with tumor diagnosis. However, the expression clinical significance of two forms circRNAs, serum exosomal, patients lung adenocarcinoma (LUAD), have not been characterized. Methods Three differentially expressed exosomal hsa_circ_0001492, hsa_circ_0001439, hsa_circ_0000896, were selected based on previous sequencing data analyses LUAD patients. The...
Abstract Background Detecting lesions in esophageal cancer (EC) is important guiding subsequent treatment. Deep learning methods based on convolutional neural networks (CNNs) and vision transformer (ViT) have made remarkable strides the field of medical image analysis due to their powerful representational capabilities. However, without prior knowledge, both traditional CNNs ViTs are susceptible disregarding critical anatomical information, including loops voids. The current methods,...
Background Prognostic models for esophageal cancer based on contrast-enhanced chest CT can aid thoracic surgeons in developing personalized treatment plans to optimize patient outcomes. However, the extensive lymphatic drainage and early lymph node metastasis of esophagus present significant challenges extracting analyzing meaningful characteristics. Previous studies have primarily focused tumor features separately, overlooking spatial correlations such as position, direction, volumetric...
Abstract Growth factor‐induced angiogenesis is being investigated in ischemic heart disease. Intracoronary and intravenous delivery are the most practical, but limited by low myocardial uptake significant systemic recirculation. The pericardial space may act as a drug reservoir with increased reduced toxicities. This study was designed to investigate tissue deposition retention of basic fibroblast growth factor (FGF‐2) after intrapericardial administration normal chronically animals. Twelve...
To compare the performance of a deep learning survival network with tumor, node, and metastasis (TNM) staging system in prediction test reliability individual treatment recommendations provided by network.In this population-based cohort study, we developed validated model using consecutive cases newly diagnosed stage I to IV esophageal cancer between January 2004 December 2015 Surveillance, Epidemiology, End Results (SEER) database. The was externally an independent from Fujian Provincial...
Abstract Emerging evidence indicates that circular RNAs (circRNAs) play important roles in disease development, especially cancers. Analysis of circRNA expression microarrays from the Gene Expression Omnibus database revealed circPIBF1 was highly upregulated lung adenocarcinoma (LUAD). The main aim this study to probe function pyroptosis LUAD cells and signal transduction pathways involved. CircPIBF1 significantly overexpressed related dismal prognosis patients with LUAD. could bind nuclear...
TRNA-derived fragments (tRFs) and tRNA-derived stress-induced RNAs (tiRNAs) are recognized as novel potential types of non-coding (ncRNAs), several tRF/tiRNA signatures closely associated with tumor diagnosis. This study aimed to analyze the expression profiles plasma tRFs/tiRNAs clarify their diagnostic value in lung adenocarcinoma (LUAD).The differential patients four early LUAD, advanced healthy controls were analyzed using high-throughput sequencing technology. Then, validated by...
The delta-shaped anastomosis has been reported to reduce anastomotic complications for a decade. However, little written comparing this technique with the circular stapler technique. objective of retrospective study was assess safety and efficacy cervical after esophagectomy. Medical records patients esophageal squamous cell carcinoma who underwent McKeown (three-incision) esophagectomy between September 2013 June 2015 were reviewed. Either stapled (CSA) or (DSA) performed at stage. clinical...
Cancer-testis antigens (CTAs) have emerged as potential clinical biomarkers targeting immunotherapy. KK-LC-1 is a member of CTAs, which has been demonstrated in variety tumors tissues and found to elicit immune responses cancer patients. However, the expression level infiltration role lung adenocarcinoma (LUAD) remains be elucidated.In this study, mRNA overall survival rate were evaluated by TIMER TCGA database LUAD was further validated serum samples using quantitative RT-PCR. The...
Abstract Introduction The current American Joint Committee on Cancer (AJCC) M1a staging of non‐small cell lung cancer (NSCLC) encompasses a wide disease spectrum, showing diverse prognosis. Methods Patients who diagnosed in an earlier period formed the training cohort, and those thereafter validation cohort. Kaplan–Meier analysis was performed for cohort by dividing stage into three subgroups: (I) malignant pleural effusion (MPE) or pericardial (MPCE); (II) separate tumor nodules...
Background: Lung cancer (LC) is ranked as a leading cause of cancer-related death worldwide. However, there are still few reliable screening biomarkers for daily clinical practice in LC. Circular RNAs (circRNAs) have been suggested valuable diagnostic various cancers. In this study, the expression and potential several circRNAs LC were explored. Methods: Seventy-two pairs tissues adjacent normal lung collected to measure relative level using quantitative reverse transcription-polymerase...
Uncommon and particularly deadly, pulmonary sarcomatoid carcinoma (PSC) is an aggressive type of lung cancer. This research aimed to create a risk categorisation nomogram forecast the overall survival (OS) patients with PSC. To develop model, 899 PSC were taken from Surveillance, Epidemiology, End Results database USA. We also used exterior verification sample 34 individuals Fujian Provincial Hospital in China. The Cox regression hazards model stepwise analysis done screen factors developing...
It is a very rare condition for patient to have right lung cancer and right-sided aortic arch simultaneously. Right lobectomy under video-assisted thoracoscopic surgery (VATS) in such challenging procedure that seldom reported. We successfully performed VATS upper 77-year-old female with Kommerell diverticulum. A woman was referred our division mixed ground-glass opacity lesion the lung. diverticulum identified by preoperative 3D CT reconstruction. radical mediastinal lymph node dissection...